Genome-Wide Meta-Analysis Unravels Interactions between Magnesium Homeostasis and Metabolic Phenotypes

Magnesium (Mg ) homeostasis is critical for metabolism. However, the genetic determinants of the renal handling of Mg , which is crucial for Mg homeostasis, and the potential influence on metabolic traits in the general population are unknown. We obtained plasma and urine parameters from 9099 indivi...

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Bibliographic Details
Published in:	Journal of the American Society of Nephrology Vol. 29; no. 1; p. 335
Main Authors:	Corre, Tanguy, Arjona, Francisco J, Hayward, Caroline, Youhanna, Sonia, de Baaij, Jeroen H F, Belge, Hendrica, Nägele, Nadine, Debaix, Huguette, Blanchard, Maxime G, Traglia, Michela, Harris, Sarah E, Ulivi, Sheila, Rueedi, Rico, Lamparter, David, Macé, Aurélien, Sala, Cinzia, Lenarduzzi, Stefania, Ponte, Belen, Pruijm, Menno, Ackermann, Daniel, Ehret, Georg, Baptista, Daniela, Polasek, Ozren, Rudan, Igor, Hurd, Toby W, Hastie, Nicholas D, Vitart, Veronique, Waeber, Geràrd, Kutalik, Zoltán, Bergmann, Sven, Vargas-Poussou, Rosa, Konrad, Martin, Gasparini, Paolo, Deary, Ian J, Starr, John M, Toniolo, Daniela, Vollenweider, Peter, Hoenderop, Joost G J, Bindels, René J M, Bochud, Murielle, Devuyst, Olivier
Format:	Journal Article
Language:	English
Published:	United States 01.01.2018
Subjects:	Adiposity - genetics ADP-Ribosylation Factors - genetics Animals Gene-Environment Interaction Genome-Wide Association Study GTP-Binding Proteins - genetics Homeostasis - genetics Humans Insulin - blood Insulin Resistance - genetics Kidney - metabolism Magnesium - administration & dosage Magnesium - blood Magnesium - urine Mice Obesity - genetics Phenotype Polymorphism, Single Nucleotide RNA, Messenger - metabolism TRPM Cation Channels - genetics Zebrafish Zebrafish Proteins - genetics Tubular transport Genetic determinants zebrafish Metabolic syndrome Gene-environment interaction Magnesium homeostasis
ISSN:	1533-3450, 1533-3450
Online Access:	Get more information
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