Aminopeptidase N Inhibitors as Pointers for Overcoming Antitumor Treatment Resistance

Aminopeptidase N (APN), also known as CD13 antigen or membrane alanyl aminopeptidase, belongs to the M1 family of the MA clan of zinc metallopeptidases. In cancer cells, the inhibition of aminopeptidases including APN causes the phenomenon termed the amino acid deprivation response (AADR), a stress...

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Bibliographic Details

Published in:	International journal of molecular sciences Vol. 23; no. 17; p. 9813
Main Authors:	Farsa, Oldřich, Ballayová, Veronika, Žáčková, Radka, Kollar, Peter, Kauerová, Tereza, Zubáč, Peter
Format:	Journal Article
Language:	English
Published:	Basel MDPI AG 01.09.2022 MDPI
Subjects:	Amino acids Apoptosis Clinical trials Enzymes Kidney cancer Lung cancer Regression analysis Treatment resistance Tumor necrosis factor-TNF
ISSN:	1422-0067, 1661-6596, 1422-0067
Online Access:	Get full text
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