Overweight and obesity in children and adolescents with Down syndrome—prevalence, determinants, consequences, and interventions: A literature review

•Youth with DS were more likely to be overweight and obesity than youth without DS.•The obesity risk increased in children with DS after age 2 years.•Likely determinants of obesity included increased leptin, decreased resting energy expenditure, comorbidities, unfavorable diet, and low physical acti...

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