Efficient isolation of encoded microparticles in a degassed micromold for highly sensitive and multiplex immunoassay with signal amplification

Multiplex detection of low-abundance protein biomarkers in biofluids can contribute to diverse biomedical fields such as early diagnosis and precision medicine. However, conventional techniques such as digital ELISA, microarray, and hydrogel-based assay still face limitations in terms of efficient p...

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Bibliographic Details
Published in:	Biosensors & bioelectronics Vol. 261; p. 116465
Main Authors:	Jang, Wookyoung, Song, E Loomee, Mun, Seok Joon, Bong, Ki Wan
Format:	Journal Article
Language:	English
Published:	England Elsevier B.V 01.10.2024
Subjects:	air biomarkers Biomarkers - urine Biosensing Techniques - methods biosensors Chorionic Gonadotropin, beta Subunit, Human - analysis Chorionic Gonadotropin, beta Subunit, Human - blood Chorionic Gonadotropin, beta Subunit, Human - isolation & purification Chorionic Gonadotropin, beta Subunit, Human - urine detection limit Dimethylpolysiloxanes - chemistry early diagnosis Equipment Design Female gonadotropins Humans Hydrogel Immunoassay Immunoassay - methods immunoassays isolation techniques Limit of Detection microarray technology Multiplex detection nanopores Particle isolation peroxidase phosphates polydimethylsiloxane precision medicine Pregnancy Protein proteomics Signal amplification urine Vascular Endothelial Growth Factor A - analysis Vascular Endothelial Growth Factor A - isolation & purification Vascular Endothelial Growth Factor A - urine vascular endothelial growth factors Immunoassay Particle isolation Hydrogel Multiplex detection Protein Signal amplification
ISSN:	0956-5663, 1873-4235, 1873-4235
Online Access:	Get full text
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