Ceritinib-related interstitial lung disease improving after treatment cessation without recurrence under either crizotinib or brigatinib: a case report

Anaplastic lymphoma kinase inhibitors (ALKi) like ceritinib are considered standard for front-line treatment of non-small cell lung cancers (NSCLC) harboring a translocation of the anaplastic lymphoma kinase (ALK) gene. We report herein a case of interstitial lung disease (ILD) that developed follow...

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Vydané v:Annals of translational medicine Ročník 7; číslo 5; s. 106
Hlavní autori: Bender, Laura, Meyer, Guillaume, Quoix, Elisabeth, Mennecier, Bertrand
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: China 01.03.2019
Predmet:
Anaplastic lymphoma kinase rearrangement (ALK rearrangement)
diffuse interstitial pneumonitis
ceritinib
non-small cell lung cancer (NSCLC)
ISSN:2305-5839, 2305-5839
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Abstract Anaplastic lymphoma kinase inhibitors (ALKi) like ceritinib are considered standard for front-line treatment of non-small cell lung cancers (NSCLC) harboring a translocation of the anaplastic lymphoma kinase (ALK) gene. We report herein a case of interstitial lung disease (ILD) that developed following a 7-month ceritinib treatment without recurrence under either crizotinib or brigatinib, two others ALKi.
AbstractList Anaplastic lymphoma kinase inhibitors (ALKi) like ceritinib are considered standard for front-line treatment of non-small cell lung cancers (NSCLC) harboring a translocation of the anaplastic lymphoma kinase (ALK) gene. We report herein a case of interstitial lung disease (ILD) that developed following a 7-month ceritinib treatment without recurrence under either crizotinib or brigatinib, two others ALKi.
Anaplastic lymphoma kinase inhibitors (ALKi) like ceritinib are considered standard for front-line treatment of non-small cell lung cancers (NSCLC) harboring a translocation of the anaplastic lymphoma kinase (ALK) gene. We report herein a case of interstitial lung disease (ILD) that developed following a 7-month ceritinib treatment without recurrence under either crizotinib or brigatinib, two others ALKi.Anaplastic lymphoma kinase inhibitors (ALKi) like ceritinib are considered standard for front-line treatment of non-small cell lung cancers (NSCLC) harboring a translocation of the anaplastic lymphoma kinase (ALK) gene. We report herein a case of interstitial lung disease (ILD) that developed following a 7-month ceritinib treatment without recurrence under either crizotinib or brigatinib, two others ALKi.
Author Meyer, Guillaume
Quoix, Elisabeth
Mennecier, Bertrand
Bender, Laura
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  givenname: Laura
  surname: Bender
  fullname: Bender, Laura
  organization: Department of Medical Oncology, University Hospital, Strasbourg, France
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  givenname: Guillaume
  surname: Meyer
  fullname: Meyer, Guillaume
  organization: Department of Pharmacy, University Hospital, Strasbourg, France
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  givenname: Elisabeth
  surname: Quoix
  fullname: Quoix, Elisabeth
  organization: Department of Pneumology, University Hospital, Strasbourg, France
– sequence: 4
  givenname: Bertrand
  surname: Mennecier
  fullname: Mennecier, Bertrand
  organization: Department of Pneumology, University Hospital, Strasbourg, France
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diffuse interstitial pneumonitis
ceritinib
non-small cell lung cancer (NSCLC)
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Title Ceritinib-related interstitial lung disease improving after treatment cessation without recurrence under either crizotinib or brigatinib: a case report
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