The Nucleotide-Free State of the Cannabinoid CB2/Gi Complex

In this issue of Cell, two papers report agonist-bound cryo-EM structures of the cannabinoid receptor, CB2, in complex with Gi. Importantly, beyond providing information that could help distinguish CB2 ligand binding from CB1, these structures support the existence of a nucleotide-free state during...

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Bibliographic Details
Published in:Cell Vol. 180; no. 4; p. 603
Main Authors: Lynch, Diane L, Hurst, Dow P, Reggio, Patricia H
Format: Journal Article
Language:English
Published: United States 20.02.2020
ISSN:1097-4172, 1097-4172
Online Access:Get more information
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