Robust causal inference using directed acyclic graphs: the R package 'dagitty'

Directed acyclic graphs (DAGs), which offer systematic representations of causal relationships, have become an established framework for the analysis of causal inference in epidemiology, often being used to determine covariate adjustment sets for minimizing confounding bias. DAGitty is a popular web...

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Vydáno v:International journal of epidemiology Ročník 45; číslo 6; s. 1887 - 1894
Hlavní autoři: Textor, Johannes, van der Zander, Benito, Gilthorpe, Mark S, Liskiewicz, Maciej, Ellison, George Th
Médium: Journal Article
Jazyk:angličtina
Vydáno: England 01.12.2016
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ISSN:1464-3685
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Abstract Directed acyclic graphs (DAGs), which offer systematic representations of causal relationships, have become an established framework for the analysis of causal inference in epidemiology, often being used to determine covariate adjustment sets for minimizing confounding bias. DAGitty is a popular web application for drawing and analysing DAGs. Here we introduce the R package 'dagitty', which provides access to all of the capabilities of the DAGitty web application within the R platform for statistical computing, and also offers several new functions. We describe how the R package 'dagitty' can be used to: evaluate whether a DAG is consistent with the dataset it is intended to represent; enumerate 'statistically equivalent' but causally different DAGs; and identify exposure-outcome adjustment sets that are valid for causally different but statistically equivalent DAGs. This functionality enables epidemiologists to detect causal misspecifications in DAGs and make robust inferences that remain valid for a range of different DAGs. The R package 'dagitty' is available through the comprehensive R archive network (CRAN) at [https://cran.r-project.org/web/packages/dagitty/]. The source code is available on github at [https://github.com/jtextor/dagitty]. The web application 'DAGitty' is free software, licensed under the GNU general public licence (GPL) version 2 and is available at [http://dagitty.net/].
AbstractList Directed acyclic graphs (DAGs), which offer systematic representations of causal relationships, have become an established framework for the analysis of causal inference in epidemiology, often being used to determine covariate adjustment sets for minimizing confounding bias. DAGitty is a popular web application for drawing and analysing DAGs. Here we introduce the R package 'dagitty', which provides access to all of the capabilities of the DAGitty web application within the R platform for statistical computing, and also offers several new functions. We describe how the R package 'dagitty' can be used to: evaluate whether a DAG is consistent with the dataset it is intended to represent; enumerate 'statistically equivalent' but causally different DAGs; and identify exposure-outcome adjustment sets that are valid for causally different but statistically equivalent DAGs. This functionality enables epidemiologists to detect causal misspecifications in DAGs and make robust inferences that remain valid for a range of different DAGs. The R package 'dagitty' is available through the comprehensive R archive network (CRAN) at [https://cran.r-project.org/web/packages/dagitty/]. The source code is available on github at [https://github.com/jtextor/dagitty]. The web application 'DAGitty' is free software, licensed under the GNU general public licence (GPL) version 2 and is available at [http://dagitty.net/].
Author Textor, Johannes
Gilthorpe, Mark S
Ellison, George Th
Liskiewicz, Maciej
van der Zander, Benito
Author_xml – sequence: 1
  givenname: Johannes
  surname: Textor
  fullname: Textor, Johannes
  organization: Department of Tumour Immunology, Radboud University Medical Center, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands
– sequence: 2
  givenname: Benito
  surname: van der Zander
  fullname: van der Zander, Benito
  organization: Institute for Theoretical Computer Science, University of Luebeck, Luebeck, Germany
– sequence: 3
  givenname: Mark S
  surname: Gilthorpe
  fullname: Gilthorpe, Mark S
  organization: Leeds Institute for Data Analytics, University of Leeds, Leeds, UK
– sequence: 4
  givenname: Maciej
  surname: Liskiewicz
  fullname: Liskiewicz, Maciej
  organization: Institute for Theoretical Computer Science, University of Luebeck, Luebeck, Germany
– sequence: 5
  givenname: George Th
  surname: Ellison
  fullname: Ellison, George Th
  organization: Leeds Institute for Data Analytics, University of Leeds, Leeds, UK
BackLink https://www.ncbi.nlm.nih.gov/pubmed/28089956$$D View this record in MEDLINE/PubMed
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PublicationTitle International journal of epidemiology
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Snippet Directed acyclic graphs (DAGs), which offer systematic representations of causal relationships, have become an established framework for the analysis of causal...
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SubjectTerms Bias
Causality
Confounding Factors (Epidemiology)
Data Interpretation, Statistical
Epidemiologic Methods
Humans
Software
Title Robust causal inference using directed acyclic graphs: the R package 'dagitty'
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