Risk and association of HLA with oxcarbazepine-induced cutaneous adverse reactions in Asians

To investigate the risk and genetic association of oxcarbazepine-induced cutaneous adverse reactions (OXC-cADRs), including Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), in Asian populations (Chinese and Thai). We prospectively enrolled patients with OXC-cADRs in Taiwan and Thailand...

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Veröffentlicht in:	Neurology Jg. 88; H. 1; S. 78
Hauptverfasser:	Chen, Chun-Bing, Hsiao, Yi-Hsin, Wu, Tony, Hsih, Mo-Song, Tassaneeyakul, Wichittra, Jorns, Teekayu P, Sukasem, Chonlaphat, Hsu, Chien-Ning, Su, Shih-Chi, Chang, Wan-Chun, Hui, Rosaline Chung-Yee, Chu, Chia-Yu, Chen, Yi-Ju, Wu, Ching-Ying, Hsu, Chao-Kai, Chiu, Tsu-Man, Sun, Pei-Lun, Lee, Hua-En, Yang, Chin-Yi, Kao, Pei-Han, Yang, Chih-Hsun, Ho, Hsin-Chun, Lin, Jing-Yi, Chang, Ya-Ching, Chen, Ming-Jing, Lu, Chun-Wei, Ng, Chau Yee, Kuo, Kang-Ling, Lin, Chien-Yio, Yang, Ching-Sheng, Chen, Ding-Ping, Chang, Pi-Yueh, Wu, Tsu-Lan, Lin, Yu-Jr, Weng, Yi-Ching, Kuo, Tseng-Tong, Hung, Shuen-Iu, Chung, Wen-Hung
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 03.01.2017
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Anticonvulsants - adverse effects Asian Continental Ancestry Group Carbamazepine - adverse effects Carbamazepine - analogs & derivatives Child Child, Preschool Epilepsy - drug therapy Female Gene Frequency Genetic Predisposition to Disease - genetics Genotype HLA-A Antigens - genetics HLA-B Antigens - genetics Humans Incidence Male Meta-Analysis as Topic Middle Aged National Health Programs - statistics & numerical data Prospective Studies Retrospective Studies Statistics, Nonparametric Stevens-Johnson Syndrome - epidemiology Stevens-Johnson Syndrome - etiology Stevens-Johnson Syndrome - genetics Taiwan Thailand Young Adult
ISSN:	1526-632X, 1526-632X
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