Colorectal Cancer‐Derived Small Extracellular Vesicles Promote Tumor Immune Evasion by Upregulating PD‐L1 Expression in Tumor‐Associated Macrophages

Tumor‐associated macrophages (TAMs) are one of the most abundant cell types in colorectal cancer (CRC) tumor microenvironment (TME). Recent studies observed complicated “cross‐talks” between cancer cells and macrophages in TME. However, the underlying mechanisms are still poorly elucidated. Here, PD...

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Bibliographic Details
Published in:	Advanced science Vol. 9; no. 9; pp. e2102620 - n/a
Main Authors:	Yin, Yuan, Liu, Bingxin, Cao, Yulin, Yao, Surui, Liu, Yuhang, Jin, Guoying, Qin, Yan, Chen, Ying, Cui, Kaisa, Zhou, Leyuan, Bian, Zehua, Fei, Bojian, Huang, Shenglin, Huang, Zhaohui
Format:	Journal Article
Language:	English
Published:	Germany John Wiley & Sons, Inc 01.03.2022 Wiley
Subjects:	Colorectal cancer Cytokines Extracellular vesicles Flow cytometry Genes Immunotherapy Lymphocytes macrophage Medical prognosis MicroRNA MicroRNAs Patients PD‐L1 small extracellular vesicles Survival analysis Tumors PD-L1 macrophage MicroRNA colorectal cancer small extracellular vesicles
ISSN:	2198-3844, 2198-3844
Online Access:	Get full text
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