First-time detection and identification of the Mycobacterium tuberculosis Complex members in extrapulmonary tuberculosis clinical samples in south Tunisia by a single tube tetraplex real-time PCR assay

Tunisia has one of the highest burdens of extrapulmonary tuberculosis (EPTB) among tuberculosis (TB) cases but the contribution of MTBC-mediated human EPTB is unknown. EPTB diagnosis is challenging due to the paucibacillary nature of clinical samples. Therefore, a need of a simplified molecular meth...

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Veröffentlicht in:	PLoS neglected tropical diseases Jg. 11; H. 5; S. e0005572
Hauptverfasser:	Siala, Mariam, Smaoui, Salma, Taktak, Wafa, Hachicha, Salma, Ghorbel, Asma, Marouane, Chema, Kammoun, Sana, Gamara, Dhikrayet, Slim, Leila, Gdoura, Radhouane, Messadi-Akrout, Férièle
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science 01.05.2017 Public Library of Science (PLoS)
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Bacteriological Techniques Biology and Life Sciences Child Child, Preschool Female Humans Infant Male Medicine and Health Sciences Microscopy Middle Aged Multiplex Polymerase Chain Reaction - methods Mycobacterium tuberculosis - classification Mycobacterium tuberculosis - genetics Mycobacterium tuberculosis - isolation & purification Real-Time Polymerase Chain Reaction - methods Research and Analysis Methods Sensitivity and Specificity Time Factors Tuberculosis - diagnosis Tuberculosis - microbiology Tunisia Young Adult
ISSN:	1935-2735, 1935-2727, 1935-2735
Online-Zugang:	Volltext
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