Bortezomib with standard chemotherapy for children with acute myeloid leukemia does not improve treatment outcomes: a report from the Children’s Oncology Group

New therapeutic strategies are needed for pediatric acute myeloid leukemia (AML) to reduce disease recurrence and treatment-related morbidity. The Children's Oncology Group Phase III AAML1031 trial tested whether the addition of bortezomib to standard chemotherapy improves survival in pediatric...

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Bibliographic Details

Published in:	Haematologica (Roma) Vol. 105; no. 7; pp. 1879 - 1886
Main Authors:	Aplenc, Richard, Meshinchi, Soheil, Sung, Lillian, Alonzo, Todd, Choi, John, Fisher, Brian, Gerbing, Robert, Hirsch, Betsy, Horton, Terzah, Kahwash, Samir, Levine, John, Loken, Michael, Brodersen, Lisa, Pollard, Jessica, Raimondi, Susana, Kolb, Edward Anders, Gamis, Alan
Format:	Journal Article
Language:	English
Published:	Italy Ferrata Storti Foundation 01.07.2020
Subjects:	Antineoplastic Combined Chemotherapy Protocols - adverse effects Bortezomib - therapeutic use Child Cytarabine - therapeutic use Disease-Free Survival Humans Leukemia, Myeloid, Acute - drug therapy Reference Standards Remission Induction Treatment Outcome
ISSN:	0390-6078, 1592-8721, 1592-8721
Online Access:	Get full text
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