Expression of cysteinyl leukotriene receptor 1 in human traumatic brain injury and brain tumors
Cysteinyl leukotrienes (CysLTs) are potent proinflammatory mediators. CysLT receptor 1 (CysLT 1) is one of the two CysLT receptors that has been cloned. Although the expression of CysLT 1 in the brain has been demonstrated by Northern blot and RT-PCR analyses, the location of CysLT 1 in the brain re...
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| Published in: | Neuroscience letters Vol. 363; no. 3; pp. 247 - 251 |
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| Main Authors: | , , , , , , , , |
| Format: | Journal Article |
| Language: | English |
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17.06.2004
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| ISSN: | 0304-3940, 1872-7972 |
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| Abstract | Cysteinyl leukotrienes (CysLTs) are potent proinflammatory mediators. CysLT receptor 1 (CysLT
1) is one of the two CysLT receptors that has been cloned. Although the expression of CysLT
1 in the brain has been demonstrated by Northern blot and RT-PCR analyses, the location of CysLT
1 in the brain remains unknown. The objective of this study was to examine the distribution of CysLT
1 by immunohistochemical analysis in human brains with traumatic injury or tumors. CysLT
1 was expressed intensely in the microvascular endothelial cells in both normal and abnormal conditions. At 8 days after traumatic injury, microvascular regeneration was found and all of the endothelial cells highly expressed CysLT
1. In gray and white matters of the normal regions of the brain, CysLT
1 was expressed weekly or not at all. However, the CysLT
1 expression increased in the neuron- and glial-appearing cells in gray and white matters after traumatic brain injury. CysLT
1 was also detected in astrocytoma, ganglioglioma and metastatic adenocarcinoma, and the expression in the neuron- and glial-appearing cells around brain tumors increased robustly. |
|---|---|
| AbstractList | Cysteinyl leukotrienes (CysLTs) are potent proinflammatory mediators. CysLT receptor 1 (CysLT
1) is one of the two CysLT receptors that has been cloned. Although the expression of CysLT
1 in the brain has been demonstrated by Northern blot and RT-PCR analyses, the location of CysLT
1 in the brain remains unknown. The objective of this study was to examine the distribution of CysLT
1 by immunohistochemical analysis in human brains with traumatic injury or tumors. CysLT
1 was expressed intensely in the microvascular endothelial cells in both normal and abnormal conditions. At 8 days after traumatic injury, microvascular regeneration was found and all of the endothelial cells highly expressed CysLT
1. In gray and white matters of the normal regions of the brain, CysLT
1 was expressed weekly or not at all. However, the CysLT
1 expression increased in the neuron- and glial-appearing cells in gray and white matters after traumatic brain injury. CysLT
1 was also detected in astrocytoma, ganglioglioma and metastatic adenocarcinoma, and the expression in the neuron- and glial-appearing cells around brain tumors increased robustly. Cysteinyl leukotrienes (CysLTs) are potent proinflammatory mediators. CysLT receptor 1 (CysLT(1)) is one of the two CysLT receptors that has been cloned. Although the expression of CysLT(1) in the brain has been demonstrated by Northern blot and RT-PCR analyses, the location of CysLT(1) in the brain remains unknown. The objective of this study was to examine the distribution of CysLT(1) by immunohistochemical analysis in human brains with traumatic injury or tumors. CysLT(1) was expressed intensely in the microvascular endothelial cells in both normal and abnormal conditions. At 8 days after traumatic injury, microvascular regeneration was found and all of the endothelial cells highly expressed CysLT(1). In gray and white matters of the normal regions of the brain, CysLT(1) was expressed weekly or not at all. However, the CysLT(1) expression increased in the neuron- and glial-appearing cells in gray and white matters after traumatic brain injury. CysLT(1) was also detected in astrocytoma, ganglioglioma and metastatic adenocarcinoma, and the expression in the neuron- and glial-appearing cells around brain tumors increased robustly. Cysteinyl leukotrienes (CysLTs) are potent proinflammatory mediators. CysLT receptor 1 (CysLT(1)) is one of the two CysLT receptors that has been cloned. Although the expression of CysLT(1) in the brain has been demonstrated by Northern blot and RT-PCR analyses, the location of CysLT(1) in the brain remains unknown. The objective of this study was to examine the distribution of CysLT(1) by immunohistochemical analysis in human brains with traumatic injury or tumors. CysLT(1) was expressed intensely in the microvascular endothelial cells in both normal and abnormal conditions. At 8 days after traumatic injury, microvascular regeneration was found and all of the endothelial cells highly expressed CysLT(1). In gray and white matters of the normal regions of the brain, CysLT(1) was expressed weekly or not at all. However, the CysLT(1) expression increased in the neuron- and glial-appearing cells in gray and white matters after traumatic brain injury. CysLT(1) was also detected in astrocytoma, ganglioglioma and metastatic adenocarcinoma, and the expression in the neuron- and glial-appearing cells around brain tumors increased robustly.Cysteinyl leukotrienes (CysLTs) are potent proinflammatory mediators. CysLT receptor 1 (CysLT(1)) is one of the two CysLT receptors that has been cloned. Although the expression of CysLT(1) in the brain has been demonstrated by Northern blot and RT-PCR analyses, the location of CysLT(1) in the brain remains unknown. The objective of this study was to examine the distribution of CysLT(1) by immunohistochemical analysis in human brains with traumatic injury or tumors. CysLT(1) was expressed intensely in the microvascular endothelial cells in both normal and abnormal conditions. At 8 days after traumatic injury, microvascular regeneration was found and all of the endothelial cells highly expressed CysLT(1). In gray and white matters of the normal regions of the brain, CysLT(1) was expressed weekly or not at all. However, the CysLT(1) expression increased in the neuron- and glial-appearing cells in gray and white matters after traumatic brain injury. CysLT(1) was also detected in astrocytoma, ganglioglioma and metastatic adenocarcinoma, and the expression in the neuron- and glial-appearing cells around brain tumors increased robustly. |
| Author | Hu, Hua Chen, Ke-Da Zhang, Wei-Ping Sheng, Wen-Wen Wei, Er-Qing Ding, Wei Yao, Hong-Tian Chen, Zhong Zhang, Lei |
| Author_xml | – sequence: 1 givenname: Wei-Ping surname: Zhang fullname: Zhang, Wei-Ping organization: Department of Pharmacology, School of Medicine, Zhejiang University, 353, Yan An Road, Hangzhou 310031, PR China – sequence: 2 givenname: Hua surname: Hu fullname: Hu, Hua organization: Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, PR China – sequence: 3 givenname: Lei surname: Zhang fullname: Zhang, Lei organization: Department of Pharmacology, School of Medicine, Zhejiang University, 353, Yan An Road, Hangzhou 310031, PR China – sequence: 4 givenname: Wei surname: Ding fullname: Ding, Wei organization: Department of Pathology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, PR China – sequence: 5 givenname: Hong-Tian surname: Yao fullname: Yao, Hong-Tian organization: Department of Pathology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, PR China – sequence: 6 givenname: Ke-Da surname: Chen fullname: Chen, Ke-Da organization: Department of Pharmacology, School of Medicine, Zhejiang University, 353, Yan An Road, Hangzhou 310031, PR China – sequence: 7 givenname: Wen-Wen surname: Sheng fullname: Sheng, Wen-Wen organization: Department of Pharmacology, School of Medicine, Zhejiang University, 353, Yan An Road, Hangzhou 310031, PR China – sequence: 8 givenname: Zhong surname: Chen fullname: Chen, Zhong organization: Department of Pharmacology, School of Medicine, Zhejiang University, 353, Yan An Road, Hangzhou 310031, PR China – sequence: 9 givenname: Er-Qing surname: Wei fullname: Wei, Er-Qing email: weieq2001@yahoo.com organization: Department of Pharmacology, School of Medicine, Zhejiang University, 353, Yan An Road, Hangzhou 310031, PR China |
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| Cites_doi | 10.1164/ajrccm.157.6.mar-1 10.1016/S1081-1206(10)62167-9 10.1038/288484a0 10.1126/science.6301011 10.1016/S1081-1206(10)62024-8 10.1161/01.ATV.0000082690.23131.CB 10.1179/016164103101201896 10.1002/glia.10057 10.1080/01616412.1992.11740094 10.4049/jimmunol.170.8.4290 10.1023/A:1023943405292 10.1089/neu.1999.16.617 10.1038/sj.bjp.0704189 10.1002/(SICI)1097-0215(19980518)76:4<547::AID-IJC17>3.0.CO;2-4 10.1016/S0014-2999(99)00037-0 10.1074/jbc.M203163200 10.1002/1097-0215(20000520)89:3<251::AID-IJC7>3.0.CO;2-5 10.1124/mol.56.3.657 10.1038/21658 |
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| Keywords | Ganglioglioma Traumatic brain injury Microvascular endothelium Astrocytoma Cysteinyl leukotriene receptor 1 Metastatic adenocarcinoma Adenocarcinoma Human Nervous system diseases Leukotriene receptor Central nervous system Malignant tumor Trauma Encephalon Endothelium Microcirculation Glioma Central nervous system disease Lesion |
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| References | Yang, Park, Sohn, Kwon, Shin, Pyo, Jin, Choi, Jou, Joe (BIB20) 2002; 38 Shinonaga, Chang, Kuwabara (BIB18) 1990; 52 Morganti-Kossmann, Hans, Lenzlinger, Dubs, Ludwig, Trentz, Kossmann (BIB14) 1999; 16 Sarau, Ames, Chambers, Ellis, Elshourbagy, Foley, Schmidt, Muccitelli, Jenkins, Murdock, Herrity, Halsey, Sathe, Muir, Nuthulaganti, Dytko, Buckley, Wilson, Bergsma, Hay (BIB16) 1999; 56 W.W. Busse, Leukotrienes and inflammation. Am. J. Respir. Crit. Care Med., 157 (1998) S210–S213; discussion S247–S248. Chibana, Ishii, Asakura, Fukuda (BIB3) 2003; 170 Dahlen, Hedqvist, Hammarstrom, Samuelsson (BIB5) 1980; 288 Inamura, Abe, Ikezaki, Fukui (BIB9) 1992; 14 Maekawa, Austen, Kanaoka (BIB13) 2002; 277 Zhang, Wei, Mei, Zhu, Zhao (BIB21) 2002; 23 Ciceri, Rabuffetti, Monopoli, Nicosia (BIB4) 2001; 133 Schuhmann, Mokhtarzadeh, Stichtenoth, Skardelly, Klinge, Gutzki, Samii, Brinker (BIB17) 2003; 25 Debinski, Gibo, Puri (BIB6) 1998; 76 Fujita, Yonetomi, Shimouchi, Takeda, Aze, Kawabata, Ohno (BIB7) 1999; 369 Kjellman, Olofsson, Hansson, Von Schantz, Lindvall, Nilsson, Salford, Sjogren, Widegren (BIB10) 2000; 89 Borish (BIB1) 2002; 88 Held-Feindt, Lutjohann, Ungefroren, Mehdorn, Mentlein (BIB8) 2003; 63 Lynch, O'Neill, Liu, Im, Sawyer, Metters, Coulombe, Abramovitz, Figueroa, Zeng, Connolly, Bai, Austin, Chateauneuf, Stocco, Greig, Kargman, Hooks, Hosfield, Williams, Ford-Hutchinson, Caskey, Evans (BIB12) 1999; 399 Samuelsson (BIB15) 1983; 220 Lotzer, Spanbroek, Hildner, Urbach, Heller, Bretschneider, Galczenski, Evans, Habenicht (BIB11) 2003; 23 Storms (BIB19) 2003; 91 Ciceri (10.1016/j.neulet.2004.03.088_BIB4) 2001; 133 Shinonaga (10.1016/j.neulet.2004.03.088_BIB18) 1990; 52 Storms (10.1016/j.neulet.2004.03.088_BIB19) 2003; 91 Fujita (10.1016/j.neulet.2004.03.088_BIB7) 1999; 369 Samuelsson (10.1016/j.neulet.2004.03.088_BIB15) 1983; 220 Maekawa (10.1016/j.neulet.2004.03.088_BIB13) 2002; 277 Chibana (10.1016/j.neulet.2004.03.088_BIB3) 2003; 170 Dahlen (10.1016/j.neulet.2004.03.088_BIB5) 1980; 288 Lotzer (10.1016/j.neulet.2004.03.088_BIB11) 2003; 23 Sarau (10.1016/j.neulet.2004.03.088_BIB16) 1999; 56 Debinski (10.1016/j.neulet.2004.03.088_BIB6) 1998; 76 Schuhmann (10.1016/j.neulet.2004.03.088_BIB17) 2003; 25 10.1016/j.neulet.2004.03.088_BIB2 Morganti-Kossmann (10.1016/j.neulet.2004.03.088_BIB14) 1999; 16 Lynch (10.1016/j.neulet.2004.03.088_BIB12) 1999; 399 Borish (10.1016/j.neulet.2004.03.088_BIB1) 2002; 88 Inamura (10.1016/j.neulet.2004.03.088_BIB9) 1992; 14 Zhang (10.1016/j.neulet.2004.03.088_BIB21) 2002; 23 Yang (10.1016/j.neulet.2004.03.088_BIB20) 2002; 38 Kjellman (10.1016/j.neulet.2004.03.088_BIB10) 2000; 89 Held-Feindt (10.1016/j.neulet.2004.03.088_BIB8) 2003; 63 |
| References_xml | – volume: 288 start-page: 484 year: 1980 end-page: 486 ident: BIB5 article-title: Leukotrienes are potent constrictors of human bronchi publication-title: Nature – volume: 133 start-page: 1323 year: 2001 end-page: 1329 ident: BIB4 article-title: Production of leukotrienes in a model of focal cerebral ischaemia in the rat publication-title: Br. J. Pharmacol. – volume: 23 start-page: E32 year: 2003 end-page: E36 ident: BIB11 article-title: Differential leukotriene receptor expression and calcium responses in endothelial cells and macrophages indicate 5-lipoxygenase-dependent circuits of inflammation and atherogenesis publication-title: Arterioscler. Thromb. Vasc. Biol. – volume: 25 start-page: 481 year: 2003 end-page: 491 ident: BIB17 article-title: Temporal profiles of cerebrospinal fluid leukotrienes, brain edema and inflammatory response following experimental brain injury publication-title: Neurol. Res. – volume: 52 start-page: 475 year: 1990 end-page: 481 ident: BIB18 article-title: Relation between macrophage infiltrates and peritumoral edema publication-title: Adv. Neurol. – volume: 38 start-page: 273 year: 2002 end-page: 280 ident: BIB20 article-title: Interleukin-13 and -4 induce death of activated microglia publication-title: Glia – volume: 88 start-page: 16 year: 2002 end-page: 22 ident: BIB1 article-title: The role of leukotrienes in upper and lower airway inflammation and the implications for treatment publication-title: Ann. Allergy Asthma Immunol. – volume: 170 start-page: 4290 year: 2003 end-page: 4295 ident: BIB3 article-title: Up-regulation of cysteinyl leukotriene 1 receptor by IL-13 enables human lung fibroblasts to respond to leukotriene C4 and produce eotaxin publication-title: J. Immunol. – volume: 89 start-page: 251 year: 2000 end-page: 258 ident: BIB10 article-title: Expression of TGF-beta isoforms, TGF-beta receptors, and SMAD molecules at different stages of human glioma publication-title: Int. J. Cancer – volume: 277 start-page: 20820 year: 2002 end-page: 20824 ident: BIB13 article-title: Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responses publication-title: J. Biol. Chem. – volume: 91 start-page: 131 year: 2003 end-page: 140 ident: BIB19 article-title: Minimal persistent inflammation, an emerging concept in the nature and treatment of allergic rhinitis: the possible role of leukotrienes publication-title: Ann. Allergy Asthma Immunol. – reference: W.W. Busse, Leukotrienes and inflammation. Am. J. Respir. Crit. Care Med., 157 (1998) S210–S213; discussion S247–S248. – volume: 14 start-page: 405 year: 1992 end-page: 410 ident: BIB9 article-title: Leukotriene C4 contents, synthase and catabolic activity in human meningiomas publication-title: Neurol. Res. – volume: 23 start-page: 871 year: 2002 end-page: 877 ident: BIB21 article-title: Neuroprotective effect of ONO-1078, a leukotriene receptor antagonist, on focal cerebral ischemia in rats publication-title: Acta Pharmacol. Sin. – volume: 63 start-page: 117 year: 2003 end-page: 127 ident: BIB8 article-title: Interaction of transforming growth factor-beta (TGF-beta) and epidermal growth factor (EGF) in human glioma cells publication-title: J. Neurooncol. – volume: 399 start-page: 789 year: 1999 end-page: 793 ident: BIB12 article-title: Characterization of the human cysteinyl leukotriene CysLT1 receptor publication-title: Nature – volume: 76 start-page: 547 year: 1998 end-page: 551 ident: BIB6 article-title: Novel way to increase targeting specificity to a human glioblastoma-associated receptor for interleukin 13 publication-title: Int. J. Cancer – volume: 16 start-page: 617 year: 1999 end-page: 628 ident: BIB14 article-title: TGF-beta is elevated in the CSF of patients with severe traumatic brain injuries and parallels blood-brain barrier function publication-title: J. Neurotrauma – volume: 369 start-page: 349 year: 1999 end-page: 356 ident: BIB7 article-title: Involvement of cysteinyl leukotrienes in biphasic increase of nasal airway resistance of antigen-induced rhinitis in guinea pigs publication-title: Eur. J. Pharmacol. – volume: 56 start-page: 657 year: 1999 end-page: 663 ident: BIB16 article-title: Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor publication-title: Mol. Pharmacol. – volume: 220 start-page: 568 year: 1983 end-page: 575 ident: BIB15 article-title: Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation publication-title: Science – ident: 10.1016/j.neulet.2004.03.088_BIB2 doi: 10.1164/ajrccm.157.6.mar-1 – volume: 91 start-page: 131 year: 2003 ident: 10.1016/j.neulet.2004.03.088_BIB19 article-title: Minimal persistent inflammation, an emerging concept in the nature and treatment of allergic rhinitis: the possible role of leukotrienes publication-title: Ann. Allergy Asthma Immunol. doi: 10.1016/S1081-1206(10)62167-9 – volume: 288 start-page: 484 year: 1980 ident: 10.1016/j.neulet.2004.03.088_BIB5 article-title: Leukotrienes are potent constrictors of human bronchi publication-title: Nature doi: 10.1038/288484a0 – volume: 220 start-page: 568 year: 1983 ident: 10.1016/j.neulet.2004.03.088_BIB15 article-title: Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation publication-title: Science doi: 10.1126/science.6301011 – volume: 88 start-page: 16 year: 2002 ident: 10.1016/j.neulet.2004.03.088_BIB1 article-title: The role of leukotrienes in upper and lower airway inflammation and the implications for treatment publication-title: Ann. Allergy Asthma Immunol. doi: 10.1016/S1081-1206(10)62024-8 – volume: 23 start-page: 871 year: 2002 ident: 10.1016/j.neulet.2004.03.088_BIB21 article-title: Neuroprotective effect of ONO-1078, a leukotriene receptor antagonist, on focal cerebral ischemia in rats publication-title: Acta Pharmacol. Sin. – volume: 23 start-page: E32 year: 2003 ident: 10.1016/j.neulet.2004.03.088_BIB11 article-title: Differential leukotriene receptor expression and calcium responses in endothelial cells and macrophages indicate 5-lipoxygenase-dependent circuits of inflammation and atherogenesis publication-title: Arterioscler. Thromb. Vasc. Biol. doi: 10.1161/01.ATV.0000082690.23131.CB – volume: 25 start-page: 481 year: 2003 ident: 10.1016/j.neulet.2004.03.088_BIB17 article-title: Temporal profiles of cerebrospinal fluid leukotrienes, brain edema and inflammatory response following experimental brain injury publication-title: Neurol. Res. doi: 10.1179/016164103101201896 – volume: 38 start-page: 273 year: 2002 ident: 10.1016/j.neulet.2004.03.088_BIB20 article-title: Interleukin-13 and -4 induce death of activated microglia publication-title: Glia doi: 10.1002/glia.10057 – volume: 14 start-page: 405 year: 1992 ident: 10.1016/j.neulet.2004.03.088_BIB9 article-title: Leukotriene C4 contents, synthase and catabolic activity in human meningiomas publication-title: Neurol. Res. doi: 10.1080/01616412.1992.11740094 – volume: 170 start-page: 4290 year: 2003 ident: 10.1016/j.neulet.2004.03.088_BIB3 article-title: Up-regulation of cysteinyl leukotriene 1 receptor by IL-13 enables human lung fibroblasts to respond to leukotriene C4 and produce eotaxin publication-title: J. Immunol. doi: 10.4049/jimmunol.170.8.4290 – volume: 63 start-page: 117 year: 2003 ident: 10.1016/j.neulet.2004.03.088_BIB8 article-title: Interaction of transforming growth factor-beta (TGF-beta) and epidermal growth factor (EGF) in human glioma cells publication-title: J. Neurooncol. doi: 10.1023/A:1023943405292 – volume: 16 start-page: 617 year: 1999 ident: 10.1016/j.neulet.2004.03.088_BIB14 article-title: TGF-beta is elevated in the CSF of patients with severe traumatic brain injuries and parallels blood-brain barrier function publication-title: J. Neurotrauma doi: 10.1089/neu.1999.16.617 – volume: 133 start-page: 1323 year: 2001 ident: 10.1016/j.neulet.2004.03.088_BIB4 article-title: Production of leukotrienes in a model of focal cerebral ischaemia in the rat publication-title: Br. J. Pharmacol. doi: 10.1038/sj.bjp.0704189 – volume: 76 start-page: 547 year: 1998 ident: 10.1016/j.neulet.2004.03.088_BIB6 article-title: Novel way to increase targeting specificity to a human glioblastoma-associated receptor for interleukin 13 publication-title: Int. J. Cancer doi: 10.1002/(SICI)1097-0215(19980518)76:4<547::AID-IJC17>3.0.CO;2-4 – volume: 52 start-page: 475 year: 1990 ident: 10.1016/j.neulet.2004.03.088_BIB18 article-title: Relation between macrophage infiltrates and peritumoral edema publication-title: Adv. Neurol. – volume: 369 start-page: 349 year: 1999 ident: 10.1016/j.neulet.2004.03.088_BIB7 article-title: Involvement of cysteinyl leukotrienes in biphasic increase of nasal airway resistance of antigen-induced rhinitis in guinea pigs publication-title: Eur. J. Pharmacol. doi: 10.1016/S0014-2999(99)00037-0 – volume: 277 start-page: 20820 year: 2002 ident: 10.1016/j.neulet.2004.03.088_BIB13 article-title: Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responses publication-title: J. Biol. Chem. doi: 10.1074/jbc.M203163200 – volume: 89 start-page: 251 year: 2000 ident: 10.1016/j.neulet.2004.03.088_BIB10 article-title: Expression of TGF-beta isoforms, TGF-beta receptors, and SMAD molecules at different stages of human glioma publication-title: Int. J. Cancer doi: 10.1002/1097-0215(20000520)89:3<251::AID-IJC7>3.0.CO;2-5 – volume: 56 start-page: 657 year: 1999 ident: 10.1016/j.neulet.2004.03.088_BIB16 article-title: Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor publication-title: Mol. Pharmacol. doi: 10.1124/mol.56.3.657 – volume: 399 start-page: 789 year: 1999 ident: 10.1016/j.neulet.2004.03.088_BIB12 article-title: Characterization of the human cysteinyl leukotriene CysLT1 receptor publication-title: Nature doi: 10.1038/21658 |
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| Snippet | Cysteinyl leukotrienes (CysLTs) are potent proinflammatory mediators. CysLT receptor 1 (CysLT
1) is one of the two CysLT receptors that has been cloned.... Cysteinyl leukotrienes (CysLTs) are potent proinflammatory mediators. CysLT receptor 1 (CysLT(1)) is one of the two CysLT receptors that has been cloned.... |
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| SubjectTerms | Adult Aged Aged, 80 and over Astrocytoma Biological and medical sciences Blotting, Northern - methods Brain Injuries - metabolism Brain Neoplasms - metabolism Cysteinyl leukotriene receptor 1 Female Fundamental and applied biological sciences. Psychology Ganglioglioma Gene Expression Humans Immunohistochemistry - methods Injuries of the nervous system and the skull. Diseases due to physical agents Male Medical sciences Membrane Proteins - genetics Membrane Proteins - metabolism Metastatic adenocarcinoma Microvascular endothelium Middle Aged Receptors, Leukotriene - genetics Receptors, Leukotriene - metabolism Reverse Transcriptase Polymerase Chain Reaction - methods Time Factors Traumas. Diseases due to physical agents Traumatic brain injury Vertebrates: nervous system and sense organs |
| Title | Expression of cysteinyl leukotriene receptor 1 in human traumatic brain injury and brain tumors |
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