Monocrotophos induced oxidative damage associates with severe acetylcholinesterase inhibition in rat brain

► Acute monocrotophos poisoning resulted in differential acetylcholinesterase inhibition in different rat brain regions. ► Neurotoxicity of monocrotophos poisoning is characterized by oxidative damage in regions of the brain that exhibit high acetylcholinesterase activity and severe acetylcholineste...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	Neurotoxicology (Park Forest South) Ročník 33; číslo 2; s. 156 - 161
Hlavní autori:	Kazi, Amajad Iqbal, Oommen, Anna
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Amsterdam Elsevier B.V 01.03.2012 Elsevier
Predmet:	Acetylcholinesterase Acetylcholinesterase - metabolism Analysis of Variance Animals Antioxidative enzymes Biological and medical sciences Body Weight - drug effects Brain - anatomy & histology Brain - drug effects Brain - enzymology Catalase - metabolism Cholinesterase Inhibitors - toxicity Disease Models, Animal Dose-Response Relationship, Drug Female Glutathione - metabolism Glutathione Peroxidase - metabolism Lacrimal Apparatus - drug effects Lipid peroxidation Lipid Peroxidation - drug effects Medical sciences Monocrotophos Monocrotophos - toxicity Muscle Strength - drug effects Neurotoxicity Syndromes - enzymology Neurotoxicity Syndromes - etiology Neurotoxicity Syndromes - pathology Organophosphate pesticide poisoning Oxidative stress Oxidative Stress - drug effects Pesticides, fertilizers and other agrochemicals toxicology Rats Rats, Wistar Salivation - drug effects Superoxide Dismutase - metabolism Time Factors Toxicology Lipid peroxidation Oxidative stress Monocrotophos Organophosphate pesticide poisoning Acetylcholinesterase Antioxidative enzymes Insecticide Rat Toxicity Central nervous system Lipids Esterases Encephalon Inhibition Peroxidation Enzyme Rodentia Pesticides Antioxidant Carboxylic ester hydrolases Vertebrata Mammalia Animal Hydrolases Inhibitor Poisoning Organophosphorus compounds
ISSN:	0161-813X, 1872-9711, 1872-9711
On-line prístup:	Získať plný text
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Buďte prvý, kto okomentuje tento záznam!