Multimodal Analysis of the Visual Pathways in Friedreich's Ataxia Reveals Novel Biomarkers

Background Optic neuropathy is a near ubiquitous feature of Friedreich's ataxia (FRDA). Previous studies have examined varying aspects of the anterior and posterior visual pathways but none so far have comprehensively evaluated the heterogeneity of degeneration across different areas of the ret...

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Veröffentlicht in:	Movement disorders Jg. 38; H. 6; S. 959 - 969
Hauptverfasser:	Thomas‐Black, Gilbert, Altmann, Daniel R., Crook, Harry, Solanky, Nita, Carrasco, Ferran Prados, Battiston, Marco, Grussu, Francesco, Yiannakas, Marios C., Kanber, Baris, Jolly, Jasleen K., Brett, Jon, Downes, Susan M., Moran, Marni, Chan, Ping K., Adewunmi, Emmanuel, Gandini Wheeler‐Kingshott, Claudia A.M., Németh, Andrea H., Festenstein, Richard, Bremner, Fion, Giunti, Paola
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Hoboken, USA John Wiley & Sons, Inc 01.06.2023 Wiley Subscription Services, Inc
Schlagworte:	Ataxia Biomarkers Clinical trials Cortex (temporal) Frataxin Friedreich Ataxia - genetics Friedreich's ataxia Humans Information processing Magnetic resonance imaging Movement disorders MRI Neurodegeneration OCT Optic Nerve Diseases Optic neuropathy Retina Retina - diagnostic imaging Thinning Tomography, Optical Coherence - methods Visual Acuity Visual cortex Visual pathways Visual Pathways - diagnostic imaging Visual perception Friedreich's ataxia OCT MRI biomarkers frataxin
ISSN:	0885-3185, 1531-8257, 1531-8257
Online-Zugang:	Volltext
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