Recent Advances in Pathology: the 2020 Annual Review Issue of The Journal of Pathology

This year's Annual Review Issue of The Journal of Pathology contains 18 invited reviews on current research areas in pathology. The subject areas reflect the broad range of topics covered by the journal and this year encompass the development and application of software in digital histopatholog...

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Vydáno v:	The Journal of pathology Ročník 250; číslo 5; s. 475 - 479
Hlavní autoři:	Herrington, C Simon, Poulsom, Richard, Coates, Philip J
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Chichester, UK John Wiley & Sons, Ltd 01.04.2020 Wiley Subscription Services, Inc
Témata:	acute response ageing algorithm anti‐sense lncRNA Apoptosis artificial intelligence astrocytoma Atherosclerosis ATXN1L autophagy biologics biomarker risk‐management Brain cancer Breast cancer cancer predisposition Capicua Cdc42 CELSR1 chemotaxis chronic inactive lesions chronic kidney disease clear cell renal cell carcinoma clinical trial clonogen collective cell migration Colorectal cancer computational pathology COPD decision support demyelinated lesions development diabetes diagnosis digital histology DNA methylation profiling DNA mismatch repair durotaxis ECM Endometrial cancer ependymoma Epigenetics Ewing's tumour exosomes foam cells gene variant interpretation Genetic disorders genome‐wide association study glioblastoma glomerulonephritis grey matter HDAC host‐directed therapy hypoxia hypoxia‐inducible factor image analysis immunity immunoediting immunotherapy inflammation inflammatory lesions interleukin‐6 invasion ionising radiation Kidney cancer late response long intergenic non‐coding RNA long non‐coding RNA Lynch syndrome macrophage macropinocytosis mass cytometry medulloblastoma Mendelian randomisation Mesenchymal stem cells mesenchymal stromal cells metabolic disorders metastasis migration miRNA monocyte multiple sclerosis neoplasia nephropathology Neuroblastoma neurodegenerative disease neurogenesis Oxidative stress oxygen Pathology PD‐L1 personalised treatment precision imaging pseudohypoxia Rac1 receptor RhoA RhoGTPase scATACseq senescence sex differences single‐cell RNAseq small airways stem cell stem cells SWI/SNF TILs tissue regeneration Toll‐like receptors translation transplantation TREM2 tuberculosis tumour microenvironment white matter X chromosome inactivation neuroblastoma scATACseq decision support CELSR1 artificial intelligence interleukin-6 late response neoplasia DNA mismatch repair Mendelian randomisation algorithm chemotaxis atherosclerosis stem cells autophagy colorectal cancer biologics digital histology tuberculosis macrophage Ewing's tumour glioblastoma mesenchymal stem cells endometrial cancer long non-coding RNA tumour microenvironment single-cell RNAseq HDAC chronic kidney disease immunity white matter ionising radiation astrocytoma inflammation metastasis PD-L1 acute response grey matter miRNA sex differences durotaxis clear cell renal cell carcinoma computational pathology multiple sclerosis clonogen cancer predisposition Breast cancer hypoxia-inducible factor ECM ependymoma tissue regeneration macropinocytosis invasion demyelinated lesions monocyte glomerulonephritis diabetes oxidative stress COPD long intergenic non-coding RNA chronic inactive lesions TREM2 image analysis RhoGTPase personalised treatment senescence SWI/SNF neurogenesis Rac1 small airways DNA methylation profiling oxygen clinical trial foam cells hypoxia metabolic disorders development medulloblastoma diagnosis RhoA transplantation collective cell migration mass cytometry immunoediting neurodegenerative disease mesenchymal stromal cells apoptosis biomarker risk-management inflammatory lesions stem cell exosomes ATXN1L X chromosome inactivation immunotherapy Toll-like receptors Cdc42 Lynch syndrome nephropathology ageing pseudohypoxia host-directed therapy gene variant interpretation anti-sense lncRNA receptor genome-wide association study migration translation precision imaging Capicua TILs
ISSN:	0022-3417, 1096-9896, 1096-9896
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Shrnutí:	This year's Annual Review Issue of The Journal of Pathology contains 18 invited reviews on current research areas in pathology. The subject areas reflect the broad range of topics covered by the journal and this year encompass the development and application of software in digital histopathology, implementation of biomarkers in pathology practice; genetics and epigenetics, and stromal influences in disease. The reviews are authored by experts in their field and provide comprehensive updates in the chosen areas, in which there has been considerable recent progress in our understanding of disease. © 2020 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
Bibliografie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23
ISSN:	0022-3417 1096-9896 1096-9896
DOI:	10.1002/path.5425