Hepatitis B virus genotypes among the Jarawas: A primitive Negrito tribe of Andaman and Nicobar Islands, India

The Jarawas, a classical hunter-gatherer tribe of Andaman and Nicobar Islands, India, were living in isolation for several centuries. They came into contact with the civilized world recently. Serological studies carried out among them revealed that hepatitis B virus (HBV) infection is hyper-endemic....

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Bibliographic Details
Published in:Archives of virology Vol. 151; no. 8; pp. 1499 - 1510
Main Authors: Murhekar, M. V., Chakravarty, R., Murhekar, K. M., Banerjee, A., Sehgal, S. C.
Format: Journal Article
Language:English
Published: Wien Springer 01.08.2006
New York, NY Springer Nature B.V
Subjects:
Amino Acid Sequence
Biological and medical sciences
Continental Population Groups
Ethnic Groups
Fundamental and applied biological sciences. Psychology
Genomes
Genotype
Genotype & phenotype
Hepatitis B
Hepatitis B - epidemiology
Hepatitis B - virology
Hepatitis B Surface Antigens - blood
Hepatitis B virus
Hepatitis B virus - classification
Hepatitis B virus - genetics
Hepatitis B virus - isolation & purification
Humans
Hunter-gatherers
India - epidemiology
Infections
Microbiology
Miscellaneous
Molecular Sequence Data
Prevalence
Serology
Virology
Indian Ocean Islands
Andaman and Nicobar
Asia
India
Nicobar Islands
Andaman Islands
Virus
Orthohepadnavirus
Genotype
Hepatitis B virus
Hepadnaviridae
ISSN:0304-8608, 1432-8798
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Summary:The Jarawas, a classical hunter-gatherer tribe of Andaman and Nicobar Islands, India, were living in isolation for several centuries. They came into contact with the civilized world recently. Serological studies carried out among them revealed that hepatitis B virus (HBV) infection is hyper-endemic. The present study was carried out to investigate the possible origin of HBV infection in Jarawas. Genotyping, RFLP analysis, sequencing, and sequence analysis revealed the prevalence of HBV genotype C, similar to genotype C detected in Thailand, Vietnam, and Myanmar. In contrast, genotype D was prevalent among other non-Jarawa tribes of the island. These data suggest that HBV infection was transmitted from Indo-China to the Andaman Islands during migration of the Jarawas many centuries ago.
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ISSN:0304-8608
1432-8798
DOI:10.1007/s00705-006-0737-8