Early Decision Making in a Randomized Phase II Trial of Atezolizumab in Biliary Tract Cancer Using a Tumor Growth Inhibition-Survival Modeling Framework

We assess the longitudinal tumor growth inhibition (TGI) metrics and overall survival (OS) predictions applied to patients with advanced biliary tract cancer (BTC) enrolled in IMbrave151 a multicenter randomized phase II, double-blind, placebo-controlled trial evaluating the efficacy and safety of a...

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Bibliographic Details
Published in:Clinical pharmacology and therapeutics Vol. 114; no. 3; p. 644
Main Authors: Shemesh, Colby S, Chan, Phyllis, Marchand, Mathilde, Gonçalves, Antonio, Vadhavkar, Shweta, Wu, Benjamin, Li, Chunze, Jin, Jin Y, Hack, Stephen P, Bruno, Rene
Format: Journal Article
Language:English
Published: United States 01.09.2023
ISSN:1532-6535, 1532-6535
Online Access:Get more information
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