Exploration of the immune response of grass carp (Ctenopharyngodon idellus) erythrocytes during bacterial infection

In teleost blood, red blood cells (RBCs) are the most common type of cell, and they differ from mammalian RBCs in having a nucleus and other organelles. As nucleated cells, teleost RBCs contribute to the immune response against pathogens, but their antibacterial mechanism remains unclear. Here, we u...

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Veröffentlicht in:Fish & shellfish immunology Jg. 149; S. 109526
Hauptverfasser: Yang, Shiyi, Bai, Yanhan, Tao, Junjie, Tu, Chengming, Chen, Bing, Huang, Xiaoman, Zhang, Linpeng, Liu, Lihan, Li, Lin, Qin, Zhendong
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England Elsevier Ltd 01.06.2024
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ISSN:1050-4648, 1095-9947, 1095-9947
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Abstract In teleost blood, red blood cells (RBCs) are the most common type of cell, and they differ from mammalian RBCs in having a nucleus and other organelles. As nucleated cells, teleost RBCs contribute to the immune response against pathogens, but their antibacterial mechanism remains unclear. Here, we utilized RNA-Seq to analyze gene expression patterns of grass carp (Ctenopharyngodon idellus) RBCs (GcRBCs) stimulated by Aeromonas hydrophila, Escherichia coli, and Staphylococcus aureus. Our transcriptomic data showed that bacterial stimulation generated many differentially expressed genes (DEGs). Furthermore, several inflammatory pathways responded to bacterial activation, and the TLR, IL-17, and tumor necrosis factor (TNF) signaling pathways were significantly activated based on Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis. Furthermore, the findings of qRT-PCR showed markedly elevated expression of various cytokines, including IL-1β, IL4, IL6, IL8, IL12, and TNFα, in GcRBCs after incubation with bacteria. Reactive oxygen species (ROS) production in GcRBCs was markedly increased after the cells were stimulated with the three bacteria, and the expression of superoxide dismutase, glutathione peroxidase, and antioxidant enzymes, including catalase, was altered. Flow cytometry analysis showed that the apoptosis rate of GcRBCs was enhanced after stimulation with the three bacteria for different times. In summary, our findings reveal that bacterial stimulation activates the immune response of GcRBCs by regulating ROS release, cytokine expression, and the antioxidant system, leading to apoptosis of GcRBCs. •The stimulation of bacteria activated the immune response of erythrocytes.•The stimulation of bacteria activated the antioxidant enzymes system of erythrocytes.•The incubation of bacteria caused apoptosis of erythrocytes.
AbstractList In teleost blood, red blood cells (RBCs) are the most common type of cell, and they differ from mammalian RBCs in having a nucleus and other organelles. As nucleated cells, teleost RBCs contribute to the immune response against pathogens, but their antibacterial mechanism remains unclear. Here, we utilized RNA-Seq to analyze gene expression patterns of grass carp (Ctenopharyngodon idellus) RBCs (GcRBCs) stimulated by Aeromonas hydrophila, Escherichia coli, and Staphylococcus aureus. Our transcriptomic data showed that bacterial stimulation generated many differentially expressed genes (DEGs). Furthermore, several inflammatory pathways responded to bacterial activation, and the TLR, IL-17, and tumor necrosis factor (TNF) signaling pathways were significantly activated based on Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis. Furthermore, the findings of qRT-PCR showed markedly elevated expression of various cytokines, including IL-1β, IL4, IL6, IL8, IL12, and TNFα, in GcRBCs after incubation with bacteria. Reactive oxygen species (ROS) production in GcRBCs was markedly increased after the cells were stimulated with the three bacteria, and the expression of superoxide dismutase, glutathione peroxidase, and antioxidant enzymes, including catalase, was altered. Flow cytometry analysis showed that the apoptosis rate of GcRBCs was enhanced after stimulation with the three bacteria for different times. In summary, our findings reveal that bacterial stimulation activates the immune response of GcRBCs by regulating ROS release, cytokine expression, and the antioxidant system, leading to apoptosis of GcRBCs.In teleost blood, red blood cells (RBCs) are the most common type of cell, and they differ from mammalian RBCs in having a nucleus and other organelles. As nucleated cells, teleost RBCs contribute to the immune response against pathogens, but their antibacterial mechanism remains unclear. Here, we utilized RNA-Seq to analyze gene expression patterns of grass carp (Ctenopharyngodon idellus) RBCs (GcRBCs) stimulated by Aeromonas hydrophila, Escherichia coli, and Staphylococcus aureus. Our transcriptomic data showed that bacterial stimulation generated many differentially expressed genes (DEGs). Furthermore, several inflammatory pathways responded to bacterial activation, and the TLR, IL-17, and tumor necrosis factor (TNF) signaling pathways were significantly activated based on Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis. Furthermore, the findings of qRT-PCR showed markedly elevated expression of various cytokines, including IL-1β, IL4, IL6, IL8, IL12, and TNFα, in GcRBCs after incubation with bacteria. Reactive oxygen species (ROS) production in GcRBCs was markedly increased after the cells were stimulated with the three bacteria, and the expression of superoxide dismutase, glutathione peroxidase, and antioxidant enzymes, including catalase, was altered. Flow cytometry analysis showed that the apoptosis rate of GcRBCs was enhanced after stimulation with the three bacteria for different times. In summary, our findings reveal that bacterial stimulation activates the immune response of GcRBCs by regulating ROS release, cytokine expression, and the antioxidant system, leading to apoptosis of GcRBCs.
In teleost blood, red blood cells (RBCs) are the most common type of cell, and they differ from mammalian RBCs in having a nucleus and other organelles. As nucleated cells, teleost RBCs contribute to the immune response against pathogens, but their antibacterial mechanism remains unclear. Here, we utilized RNA-Seq to analyze gene expression patterns of grass carp (Ctenopharyngodon idellus) RBCs (GcRBCs) stimulated by Aeromonas hydrophila, Escherichia coli, and Staphylococcus aureus. Our transcriptomic data showed that bacterial stimulation generated many differentially expressed genes (DEGs). Furthermore, several inflammatory pathways responded to bacterial activation, and the TLR, IL-17, and tumor necrosis factor (TNF) signaling pathways were significantly activated based on Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis. Furthermore, the findings of qRT-PCR showed markedly elevated expression of various cytokines, including IL-1β, IL4, IL6, IL8, IL12, and TNFα, in GcRBCs after incubation with bacteria. Reactive oxygen species (ROS) production in GcRBCs was markedly increased after the cells were stimulated with the three bacteria, and the expression of superoxide dismutase, glutathione peroxidase, and antioxidant enzymes, including catalase, was altered. Flow cytometry analysis showed that the apoptosis rate of GcRBCs was enhanced after stimulation with the three bacteria for different times. In summary, our findings reveal that bacterial stimulation activates the immune response of GcRBCs by regulating ROS release, cytokine expression, and the antioxidant system, leading to apoptosis of GcRBCs.
In teleost blood, red blood cells (RBCs) are the most common type of cell, and they differ from mammalian RBCs in having a nucleus and other organelles. As nucleated cells, teleost RBCs contribute to the immune response against pathogens, but their antibacterial mechanism remains unclear. Here, we utilized RNA-Seq to analyze gene expression patterns of grass carp (Ctenopharyngodon idellus) RBCs (GcRBCs) stimulated by Aeromonas hydrophila, Escherichia coli, and Staphylococcus aureus. Our transcriptomic data showed that bacterial stimulation generated many differentially expressed genes (DEGs). Furthermore, several inflammatory pathways responded to bacterial activation, and the TLR, IL-17, and tumor necrosis factor (TNF) signaling pathways were significantly activated based on Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis. Furthermore, the findings of qRT-PCR showed markedly elevated expression of various cytokines, including IL-1β, IL4, IL6, IL8, IL12, and TNFα, in GcRBCs after incubation with bacteria. Reactive oxygen species (ROS) production in GcRBCs was markedly increased after the cells were stimulated with the three bacteria, and the expression of superoxide dismutase, glutathione peroxidase, and antioxidant enzymes, including catalase, was altered. Flow cytometry analysis showed that the apoptosis rate of GcRBCs was enhanced after stimulation with the three bacteria for different times. In summary, our findings reveal that bacterial stimulation activates the immune response of GcRBCs by regulating ROS release, cytokine expression, and the antioxidant system, leading to apoptosis of GcRBCs. •The stimulation of bacteria activated the immune response of erythrocytes.•The stimulation of bacteria activated the antioxidant enzymes system of erythrocytes.•The incubation of bacteria caused apoptosis of erythrocytes.
ArticleNumber 109526
Author Huang, Xiaoman
Li, Lin
Chen, Bing
Yang, Shiyi
Tao, Junjie
Zhang, Linpeng
Qin, Zhendong
Liu, Lihan
Bai, Yanhan
Tu, Chengming
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  givenname: Yanhan
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  givenname: Junjie
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  email: chenbing114@163.com
  organization: Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China
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  givenname: Xiaoman
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  organization: Guangdong Provincial Water Environment and Aquatic Products Security Engineering Technology Research Center, Guangzhou Key Laboratory of Aquatic Animal Diseases and Waterfowl Breeding, College of Animal Sciences and Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, Guangdong Province, 510222, China
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  givenname: Lin
  surname: Li
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  email: linli@zhku.edu.cn
  organization: Guangdong Provincial Water Environment and Aquatic Products Security Engineering Technology Research Center, Guangzhou Key Laboratory of Aquatic Animal Diseases and Waterfowl Breeding, College of Animal Sciences and Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, Guangdong Province, 510222, China
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  givenname: Zhendong
  surname: Qin
  fullname: Qin, Zhendong
  email: qinzhendongsc@163.com
  organization: Guangdong Provincial Water Environment and Aquatic Products Security Engineering Technology Research Center, Guangzhou Key Laboratory of Aquatic Animal Diseases and Waterfowl Breeding, College of Animal Sciences and Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, Guangdong Province, 510222, China
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Cites_doi 10.1080/01926230701320337
10.1007/s13258-016-0437-z
10.1081/IPH-200042323
10.3389/fimmu.2017.01458
10.1016/S0021-9258(18)31379-6
10.1007/978-1-0716-2313-8_22
10.1111/j.1399-6576.1996.tb04475.x
10.1016/j.fsi.2019.06.008
10.1126/science.abi5200
10.1182/blood.V89.11.4175
10.3389/fimmu.2019.00613
10.1038/s41591-019-0675-0
10.1016/j.fsi.2021.10.001
10.1038/nri3423
10.3389/fimmu.2020.01914
10.12688/f1000research.12985.1
10.1016/j.aquaculture.2023.740071
10.1016/j.fsi.2019.04.044
10.1172/JCI115442
10.1111/j.1432-0436.1991.tb00880.x
10.1016/S0076-6879(81)77046-0
10.1056/NEJM197202242860806
10.3389/fphys.2014.00084
10.1081/IPH-120016050
10.1016/j.dci.2011.03.011
10.3389/fimmu.2019.01055
10.1023/A:1009616228304
10.3390/cells8050386
10.1067/mai.2003.108
10.1016/0076-6879(95)52007-4
10.1016/j.aquatox.2012.11.005
10.1371/journal.pone.0026998
10.1159/000485089
10.1038/nrmicro1004
10.1083/jcb.201708007
10.1186/1743-422X-5-36
10.1016/j.dci.2011.05.001
10.3390/antiox10020313
10.1016/j.fsi.2018.03.030
10.1016/j.fsi.2020.09.036
10.1038/bjc.1972.33
10.1016/j.fsi.2015.05.049
10.1038/s43016-020-0127-5
10.1016/j.aquaculture.2020.735956
10.1038/nrm2256
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Keywords Antioxidant system
Inflammation
GcRBCs
ROS
Apoptosis
Language English
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References Chen, Yuan, Su, Liu (bib17) 2019; 90
Kerr, Wyllie, Currie (bib45) 1972; 26
Bjørndal, Dey, Tusvik (bib2) 2024; 578
Workenhe, Kibenge, Wright, Wadowska, Groman, Kibenge (bib20) 2008; 5
Li, Feng, Jiang, Liu, Jiang, Li, Zhou (bib50) 2013; 126
Kristiansson, Soop, Saraste, Sundqvist (bib31) 1996; 40
Pereiro, Romero, Díaz-Rosales, Estepa, Figueras, Novoa (bib23) 2017; 8
Secombes, Wang, Bird (bib34) 2011; 35
Wang, Branicky, Noë, Hekimi (bib42) 2018; 217
Nombela, Carrion, Puente-Marin, Chico, Mercado, Perez, Coll, Del Ortega-Villaizan (bib22) 2017; 6
Lu, Yang, Zhang, Zhan, Li, Shi, Li, Zhao, Li, Lin, Qin (bib12) 2021; 532
Yang, Chen, Lu, Xu, Li, Yang, Li, Lin, Qin (bib15) 2021; 12
Neote, Darbonne, Ogez, Horuk, Schall (bib29) 1993; 268
D'Autréaux, Toledano (bib35) 2007; 8
Qin, Babu, Wan, Zhou, Liang, Muhammad, Zhao, Li, Lan, Lin (bib16) 2018; 77
Savan, Sakai (bib32) 2006; 1
Nikinmaa, Crespel (bib8) 2022; 2498
Medzhitov (bib26) 2021; 374
Morera, Roher, Ribas, Balasch, Doñate, Callol, Boltaña, Roberts, Goetz, Goetz, MacKenzie (bib7) 2011; 6
Anderson, Asche, Garlock, Chu (bib1) 2017
Watson, Rotstein, Jimenez, Parodo, Marshall (bib48) 1997; 89
Xu, Yang, Sarath Babu, Chen, Li, Yang, Li, Li, Lin, Qin (bib14) 2021; 119
Nathan, Cunningham-Bussel (bib37) 2013; 13
Stentiford, Bateman, Hinchliffe, Bass, Hartnell, Santos, Devlin, Feist, Taylor, Verner-Jeffreys, van Aerle, Peeler, Higman, Smith, Baines, Behringer, Katsiadaki, Froehlich, Tyler (bib3) 2020; 1
Passantino, Altamura, Cianciotta, Patruno, Tafaro, Jirillo, Passantino (bib18) 2002; 24
Pierce, Parchment, Lewellyn (bib47) 1991; 46
Dahle, Wessel, Timmerhaus, Nyman, Jørgensen, Rimstad, Krasnov (bib9) 2015; 45
Fang (bib39) 2004; 2
Wendel (bib43) 1981; 77
Mohanty, Nagababu, Rifkind (bib41) 2014; 5
Chico, Salvador-Mira, Nombela, Puente-Marin, Ciordia, Mena, Perez, Coll, Guzman, Encinar, Mercado, Del Ortega-Villaizan (bib6) 2019; 10
He, He, Farrar, Ji, Liu, Ma (bib38) 2017; 44
Finch, Lenfant (bib4) 1972; 286
Passantino, Altamura, Cianciotta, Jirillo, Ribaud, Jirillo, Passantino (bib19) 2004; 26
Borish, Steinke (bib28) 2003; 111
Nombela, Puente-Marin, Chico, Villena, Carracedo, Ciordia, Mena, Mercado, Perez, Coll, Estepa, Del Ortega-Villaizan (bib21) 2017; 6
Nombela, Requena-Platek, Morales-Lange, Chico, Puente-Marin, Ciordia, Mena, Coll, Perez, Mercado, Del Ortega-Villaizan (bib24) 2019; 8
Sun, Li, Ning, Sun (bib25) 2020; 21
Elmore (bib46) 2007; 35
Stosik, Tokarz-Deptuła, Deptuła, Deptuła (bib40) 2020; 11
Furman, Campisi, Verdin, Carrera-Bastos, Targ, Franceschi, Ferrucci, Gilroy, Fasano, Miller, Miller, Mantovani, Weyand, Barzilai, Goronzy, Rando, Effros, Lucia, Kleinstreuer, Slavich (bib27) 2019; 25
Puente-Marin, Thwaite, Mercado, Coll, Roher, Del Ortega-Villaizan (bib10) 2019; 10
Qin, Vijayaraman, Lin, Dai, Zhao, Xie, Lin, Wu, Li, Lin (bib13) 2019; 92
Alejo, Tafalla (bib33) 2011; 35
Jeong, An, Kim, Park (bib5) 2016; 38
Ursini, Maiorino, Brigelius-Flohé, Aumann, Roveri, Schomburg, Flohé (bib44) 1995; 252
Darbonne, Rice, Mohler, Apple, Hébert, Valente, Baker (bib30) 1991; 88
Yang, Lu, Li, Shi, Zhan, Zhao, Li, Li, Lin, Qin (bib11) 2021; 112
Simon, Haj-Yehia, Levi-Schaffer (bib49) 2000; 5
Herb, Schramm (bib36) 2021; 10
Herb (10.1016/j.fsi.2024.109526_bib36) 2021; 10
Finch (10.1016/j.fsi.2024.109526_bib4) 1972; 286
Fang (10.1016/j.fsi.2024.109526_bib39) 2004; 2
Nathan (10.1016/j.fsi.2024.109526_bib37) 2013; 13
D'Autréaux (10.1016/j.fsi.2024.109526_bib35) 2007; 8
Watson (10.1016/j.fsi.2024.109526_bib48) 1997; 89
Pierce (10.1016/j.fsi.2024.109526_bib47) 1991; 46
Wang (10.1016/j.fsi.2024.109526_bib42) 2018; 217
Qin (10.1016/j.fsi.2024.109526_bib16) 2018; 77
Savan (10.1016/j.fsi.2024.109526_bib32) 2006; 1
Jeong (10.1016/j.fsi.2024.109526_bib5) 2016; 38
Stosik (10.1016/j.fsi.2024.109526_bib40) 2020; 11
Ursini (10.1016/j.fsi.2024.109526_bib44) 1995; 252
Li (10.1016/j.fsi.2024.109526_bib50) 2013; 126
Yang (10.1016/j.fsi.2024.109526_bib11) 2021; 112
Borish (10.1016/j.fsi.2024.109526_bib28) 2003; 111
Secombes (10.1016/j.fsi.2024.109526_bib34) 2011; 35
Puente-Marin (10.1016/j.fsi.2024.109526_bib10) 2019; 10
Kerr (10.1016/j.fsi.2024.109526_bib45) 1972; 26
Nombela (10.1016/j.fsi.2024.109526_bib21) 2017; 6
Nombela (10.1016/j.fsi.2024.109526_bib24) 2019; 8
Passantino (10.1016/j.fsi.2024.109526_bib19) 2004; 26
Yang (10.1016/j.fsi.2024.109526_bib15) 2021; 12
Elmore (10.1016/j.fsi.2024.109526_bib46) 2007; 35
Medzhitov (10.1016/j.fsi.2024.109526_bib26) 2021; 374
Bjørndal (10.1016/j.fsi.2024.109526_bib2) 2024; 578
Chen (10.1016/j.fsi.2024.109526_bib17) 2019; 90
Nombela (10.1016/j.fsi.2024.109526_bib22) 2017; 6
Alejo (10.1016/j.fsi.2024.109526_bib33) 2011; 35
Pereiro (10.1016/j.fsi.2024.109526_bib23) 2017; 8
Chico (10.1016/j.fsi.2024.109526_bib6) 2019; 10
Mohanty (10.1016/j.fsi.2024.109526_bib41) 2014; 5
Stentiford (10.1016/j.fsi.2024.109526_bib3) 2020; 1
Xu (10.1016/j.fsi.2024.109526_bib14) 2021; 119
Kristiansson (10.1016/j.fsi.2024.109526_bib31) 1996; 40
Wendel (10.1016/j.fsi.2024.109526_bib43) 1981; 77
Nikinmaa (10.1016/j.fsi.2024.109526_bib8) 2022; 2498
Workenhe (10.1016/j.fsi.2024.109526_bib20) 2008; 5
Anderson (10.1016/j.fsi.2024.109526_bib1) 2017
Qin (10.1016/j.fsi.2024.109526_bib13) 2019; 92
Sun (10.1016/j.fsi.2024.109526_bib25) 2020; 21
Neote (10.1016/j.fsi.2024.109526_bib29) 1993; 268
Simon (10.1016/j.fsi.2024.109526_bib49) 2000; 5
Darbonne (10.1016/j.fsi.2024.109526_bib30) 1991; 88
Passantino (10.1016/j.fsi.2024.109526_bib18) 2002; 24
Morera (10.1016/j.fsi.2024.109526_bib7) 2011; 6
Furman (10.1016/j.fsi.2024.109526_bib27) 2019; 25
Lu (10.1016/j.fsi.2024.109526_bib12) 2021; 532
Dahle (10.1016/j.fsi.2024.109526_bib9) 2015; 45
He (10.1016/j.fsi.2024.109526_bib38) 2017; 44
References_xml – volume: 5
  start-page: 36
  year: 2008
  ident: bib20
  article-title: Infectious salmon anaemia virus replication and induction of alpha interferon in Atlantic salmon erythrocytes
  publication-title: Virol. J.
– volume: 35
  start-page: 1336
  year: 2011
  end-page: 1345
  ident: bib34
  article-title: The interleukins of fish
  publication-title: Dev. Comp. Immunol.
– volume: 77
  start-page: 164
  year: 2018
  end-page: 174
  ident: bib16
  article-title: Transcriptome analysis of Pacific white shrimp (
  publication-title: Fish Shellfish Immunol.
– volume: 286
  start-page: 407
  year: 1972
  end-page: 415
  ident: bib4
  article-title: Oxygen transport in man
  publication-title: N. Engl. J. Med.
– volume: 374
  start-page: 1070
  year: 2021
  end-page: 1075
  ident: bib26
  article-title: The spectrum of inflammatory responses
  publication-title: Science
– volume: 38
  start-page: 931
  year: 2016
  end-page: 938
  ident: bib5
  article-title: Cooperation of erythrocytes with leukocytes in immune response of a teleost
  publication-title: Genes Genom
– volume: 5
  start-page: 415
  year: 2000
  end-page: 418
  ident: bib49
  article-title: Role of reactive oxygen species (ROS) in apoptosis induction
  publication-title: Apoptosis
– volume: 45
  start-page: 780
  year: 2015
  end-page: 790
  ident: bib9
  article-title: Transcriptome analyses of Atlantic salmon (
  publication-title: Fish Shellfish Immunol.
– volume: 111
  start-page: S460
  year: 2003
  end-page: S475
  ident: bib28
  article-title: 2. Cytokines and chemokines
  publication-title: J. Allergy Clin. Immunol.
– volume: 26
  start-page: 573
  year: 2004
  end-page: 585
  ident: bib19
  article-title: Maturation of fish erythrocytes coincides with changes in their morphology, enhanced ability to interact with
  publication-title: Immunopharmacol. Immunotoxicol.
– volume: 25
  start-page: 1822
  year: 2019
  end-page: 1832
  ident: bib27
  article-title: Chronic inflammation in the etiology of disease across the life span
  publication-title: Nat. Med.
– volume: 26
  start-page: 239
  year: 1972
  end-page: 257
  ident: bib45
  article-title: Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
  publication-title: Br. J. Cancer
– volume: 532
  start-page: 1
  year: 2021
  end-page: 11
  ident: bib12
  article-title: infection activates death receptor apoptosis pathway in the red blood cells of grass carp (
  publication-title: Aquaculture
– volume: 10
  start-page: 1
  year: 2019
  end-page: 15
  ident: bib6
  article-title: IFIT5 participates in the antiviral mechanisms of rainbow trout red blood cells
  publication-title: Front. Immunol.
– volume: 90
  start-page: 376
  year: 2019
  end-page: 384
  ident: bib17
  article-title: Hematological analysis of
  publication-title: Fish Shellfish Immunol.
– volume: 268
  start-page: 12247
  year: 1993
  end-page: 12249
  ident: bib29
  article-title: Identification of a promiscuous inflammatory peptide receptor on the surface of red blood cells
  publication-title: J. Biol. Chem.
– volume: 10
  year: 2021
  ident: bib36
  article-title: Functions of ROS in macrophages and antimicrobial immunity
  publication-title: Antioxidants
– volume: 8
  start-page: 1458
  year: 2017
  ident: bib23
  article-title: Nucleated teleost erythrocytes play an nk-lysin- and autophagy-dependent role in antiviral immunity
  publication-title: Front. Immunol.
– volume: 89
  start-page: 4175
  year: 1997
  end-page: 4181
  ident: bib48
  article-title: Augmented intracellular glutathione inhibits Fas-triggered apoptosis of activated human neutrophils
  publication-title: Blood
– volume: 24
  start-page: 665
  year: 2002
  end-page: 678
  ident: bib18
  article-title: Fish immunology. I. Binding and engulfment of
  publication-title: Immunopharmacol. Immunotoxicol.
– volume: 77
  start-page: 325
  year: 1981
  end-page: 333
  ident: bib43
  article-title: Glutathione peroxidase
  publication-title: Methods Enzymol.
– volume: 92
  start-page: 331
  year: 2019
  end-page: 340
  ident: bib13
  article-title: Antibacterial activity of erythrocyte from grass carp (
  publication-title: Fish Shellfish Immunol.
– volume: 1
  start-page: 89
  year: 2006
  end-page: 101
  ident: bib32
  article-title: Genomics of fish cytokines
  publication-title: Comp. Biochem. Physiol., Part D: Genomics Proteomics
– volume: 112
  start-page: 159
  year: 2021
  end-page: 167
  ident: bib11
  article-title: induced ferroptosis in red blood cells of grass carp (
  publication-title: Fish Shellfish Immunol.
– volume: 6
  start-page: 1958
  year: 2017
  ident: bib21
  article-title: Identification of diverse defense mechanisms in rainbow trout red blood cells in response to halted replication of VHS virus
  publication-title: F1000Res
– volume: 6
  year: 2011
  ident: bib7
  article-title: RNA-Seq reveals an integrated immune response in nucleated erythrocytes
  publication-title: PLoS One
– volume: 88
  start-page: 1362
  year: 1991
  end-page: 1369
  ident: bib30
  article-title: Red blood cells are a sink for interleukin 8, a leukocyte chemotaxin
  publication-title: J. Clin. Invest.
– volume: 5
  start-page: 84
  year: 2014
  ident: bib41
  article-title: Red blood cell oxidative stress impairs oxygen delivery and induces red blood cell aging
  publication-title: Front. Physiol.
– volume: 252
  start-page: 38
  year: 1995
  end-page: 53
  ident: bib44
  article-title: Diversity of glutathione peroxidases
  publication-title: Methods Enzymol.
– volume: 21
  year: 2020
  ident: bib25
  article-title: Transcriptome analysis of
  publication-title: Int. J. Mol. Sci.
– volume: 35
  start-page: 495
  year: 2007
  end-page: 516
  ident: bib46
  article-title: Apoptosis: a review of programmed cell death
  publication-title: Toxicol. Pathol.
– volume: 126
  start-page: 169
  year: 2013
  end-page: 179
  ident: bib50
  article-title: Oxidative stress parameters and anti-apoptotic response to hydroxyl radicals in fish erythrocytes: protective effects of glutamine, alanine, citrulline and proline
  publication-title: Aquat. Toxicol.
– volume: 11
  year: 2020
  ident: bib40
  article-title: Immune functions of erythrocytes in osteichthyes
  publication-title: Front. Immunol.
– volume: 1
  start-page: 468
  year: 2020
  end-page: 474
  ident: bib3
  article-title: Sustainable aquaculture through the one health lens
  publication-title: Nat. Food
– volume: 217
  start-page: 1915
  year: 2018
  end-page: 1928
  ident: bib42
  article-title: Superoxide dismutases: dual roles in controlling ROS damage and regulating ROS signaling
  publication-title: J. Cell Biol.
– volume: 578
  year: 2024
  ident: bib2
  article-title: Economic analysis of the contributions of aquaculture to future food security
  publication-title: Aquaculture
– volume: 13
  start-page: 349
  year: 2013
  end-page: 361
  ident: bib37
  article-title: Beyond oxidative stress: an immunologist's guide to reactive oxygen species
  publication-title: Nat. Rev. Immunol.
– volume: 2
  start-page: 820
  year: 2004
  end-page: 832
  ident: bib39
  article-title: Antimicrobial reactive oxygen and nitrogen species: concepts and controversies
  publication-title: Nat. Rev. Microbiol.
– volume: 12
  year: 2021
  ident: bib15
  article-title: The antibacterial activity of erythrocytes from goose (
  publication-title: Front. Immunol.
– volume: 44
  start-page: 532
  year: 2017
  end-page: 553
  ident: bib38
  article-title: Antioxidants maintain cellular redox homeostasis by elimination of reactive oxygen species
  publication-title: Cell. Physiol. Biochem.
– volume: 6
  start-page: 1968
  year: 2017
  ident: bib22
  article-title: Infectious pancreatic necrosis virus triggers antiviral immune response in rainbow trout red blood cells, despite not being infective
  publication-title: F1000Res
– volume: 10
  start-page: 1055
  year: 2019
  ident: bib10
  article-title: Fish red blood cells modulate immune genes in response to bacterial inclusion bodies made of TNFα and a G-VHSV fragment
  publication-title: Front. Immunol.
– volume: 40
  start-page: 496
  year: 1996
  end-page: 501
  ident: bib31
  article-title: Cytokines in stored red blood cell concentrates: promoters of systemic inflammation and simulators of acute transfusion reactions?
  publication-title: Acta Anaesthesiol. Scand.
– volume: 8
  start-page: 813
  year: 2007
  end-page: 824
  ident: bib35
  article-title: ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis
  publication-title: Nat. Rev. Mol. Cell Biol.
– start-page: 159
  year: 2017
  end-page: 173
  ident: bib1
  article-title: Aquaculture: its role in the future of food
  publication-title: World Agricultural Resources and Food Security: International Food Security/
– volume: 2498
  start-page: 373
  year: 2022
  end-page: 385
  ident: bib8
  article-title: Functional genomics of fish erythrocytes
  publication-title: Methods Mol. Biol.
– volume: 8
  year: 2019
  ident: bib24
  article-title: Rainbow trout red blood cells exposed to viral hemorrhagic septicemia virus up-regulate antigen-processing mechanisms and MHC I&II, CD86, and CD83 antigen-presenting cell markers
  publication-title: Cells
– volume: 119
  start-page: 96
  year: 2021
  end-page: 104
  ident: bib14
  article-title: The antibacterial activity of erythrocytes from
  publication-title: Fish Shellfish Immunol.
– volume: 35
  start-page: 1215
  year: 2011
  end-page: 1222
  ident: bib33
  article-title: Chemokines in teleost fish species
  publication-title: Dev. Comp. Immunol.
– volume: 46
  start-page: 181
  year: 1991
  end-page: 186
  ident: bib47
  article-title: Hydrogen peroxide as a mediator of programmed cell death in the blastocyst
  publication-title: Differentiation
– start-page: 159
  year: 2017
  ident: 10.1016/j.fsi.2024.109526_bib1
  article-title: Aquaculture: its role in the future of food
– volume: 12
  year: 2021
  ident: 10.1016/j.fsi.2024.109526_bib15
  article-title: The antibacterial activity of erythrocytes from goose (Anser domesticus) can Be associated with phagocytosis and respiratory burst generation
  publication-title: Front. Immunol.
– volume: 35
  start-page: 495
  year: 2007
  ident: 10.1016/j.fsi.2024.109526_bib46
  article-title: Apoptosis: a review of programmed cell death
  publication-title: Toxicol. Pathol.
  doi: 10.1080/01926230701320337
– volume: 38
  start-page: 931
  year: 2016
  ident: 10.1016/j.fsi.2024.109526_bib5
  article-title: Cooperation of erythrocytes with leukocytes in immune response of a teleost Oplegnathus fasciatus
  publication-title: Genes Genom
  doi: 10.1007/s13258-016-0437-z
– volume: 26
  start-page: 573
  year: 2004
  ident: 10.1016/j.fsi.2024.109526_bib19
  article-title: Maturation of fish erythrocytes coincides with changes in their morphology, enhanced ability to interact with Candida albicans and release of cytokine-like factors active upon autologous macrophages
  publication-title: Immunopharmacol. Immunotoxicol.
  doi: 10.1081/IPH-200042323
– volume: 1
  start-page: 89
  year: 2006
  ident: 10.1016/j.fsi.2024.109526_bib32
  article-title: Genomics of fish cytokines
  publication-title: Comp. Biochem. Physiol., Part D: Genomics Proteomics
– volume: 8
  start-page: 1458
  year: 2017
  ident: 10.1016/j.fsi.2024.109526_bib23
  article-title: Nucleated teleost erythrocytes play an nk-lysin- and autophagy-dependent role in antiviral immunity
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2017.01458
– volume: 268
  start-page: 12247
  year: 1993
  ident: 10.1016/j.fsi.2024.109526_bib29
  article-title: Identification of a promiscuous inflammatory peptide receptor on the surface of red blood cells
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(18)31379-6
– volume: 2498
  start-page: 373
  year: 2022
  ident: 10.1016/j.fsi.2024.109526_bib8
  article-title: Functional genomics of fish erythrocytes
  publication-title: Methods Mol. Biol.
  doi: 10.1007/978-1-0716-2313-8_22
– volume: 40
  start-page: 496
  year: 1996
  ident: 10.1016/j.fsi.2024.109526_bib31
  article-title: Cytokines in stored red blood cell concentrates: promoters of systemic inflammation and simulators of acute transfusion reactions?
  publication-title: Acta Anaesthesiol. Scand.
  doi: 10.1111/j.1399-6576.1996.tb04475.x
– volume: 92
  start-page: 331
  year: 2019
  ident: 10.1016/j.fsi.2024.109526_bib13
  article-title: Antibacterial activity of erythrocyte from grass carp (Ctenopharyngodon idella) is associated with phagocytosis and reactive oxygen species generation
  publication-title: Fish Shellfish Immunol.
  doi: 10.1016/j.fsi.2019.06.008
– volume: 374
  start-page: 1070
  year: 2021
  ident: 10.1016/j.fsi.2024.109526_bib26
  article-title: The spectrum of inflammatory responses
  publication-title: Science
  doi: 10.1126/science.abi5200
– volume: 89
  start-page: 4175
  year: 1997
  ident: 10.1016/j.fsi.2024.109526_bib48
  article-title: Augmented intracellular glutathione inhibits Fas-triggered apoptosis of activated human neutrophils
  publication-title: Blood
  doi: 10.1182/blood.V89.11.4175
– volume: 10
  start-page: 1
  year: 2019
  ident: 10.1016/j.fsi.2024.109526_bib6
  article-title: IFIT5 participates in the antiviral mechanisms of rainbow trout red blood cells
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2019.00613
– volume: 25
  start-page: 1822
  year: 2019
  ident: 10.1016/j.fsi.2024.109526_bib27
  article-title: Chronic inflammation in the etiology of disease across the life span
  publication-title: Nat. Med.
  doi: 10.1038/s41591-019-0675-0
– volume: 119
  start-page: 96
  year: 2021
  ident: 10.1016/j.fsi.2024.109526_bib14
  article-title: The antibacterial activity of erythrocytes from Clarias fuscus associated with phagocytosis and respiratory burst generation
  publication-title: Fish Shellfish Immunol.
  doi: 10.1016/j.fsi.2021.10.001
– volume: 13
  start-page: 349
  year: 2013
  ident: 10.1016/j.fsi.2024.109526_bib37
  article-title: Beyond oxidative stress: an immunologist's guide to reactive oxygen species
  publication-title: Nat. Rev. Immunol.
  doi: 10.1038/nri3423
– volume: 11
  year: 2020
  ident: 10.1016/j.fsi.2024.109526_bib40
  article-title: Immune functions of erythrocytes in osteichthyes
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2020.01914
– volume: 6
  start-page: 1958
  year: 2017
  ident: 10.1016/j.fsi.2024.109526_bib21
  article-title: Identification of diverse defense mechanisms in rainbow trout red blood cells in response to halted replication of VHS virus
  publication-title: F1000Res
  doi: 10.12688/f1000research.12985.1
– volume: 578
  year: 2024
  ident: 10.1016/j.fsi.2024.109526_bib2
  article-title: Economic analysis of the contributions of aquaculture to future food security
  publication-title: Aquaculture
  doi: 10.1016/j.aquaculture.2023.740071
– volume: 90
  start-page: 376
  year: 2019
  ident: 10.1016/j.fsi.2024.109526_bib17
  article-title: Hematological analysis of Ctenopharyngodon idella, Megalobrama amblycephala and Pelteobagrus fulvidraco: morphology, ultrastructure, cytochemistry and quantification of peripheral blood cells
  publication-title: Fish Shellfish Immunol.
  doi: 10.1016/j.fsi.2019.04.044
– volume: 88
  start-page: 1362
  year: 1991
  ident: 10.1016/j.fsi.2024.109526_bib30
  article-title: Red blood cells are a sink for interleukin 8, a leukocyte chemotaxin
  publication-title: J. Clin. Invest.
  doi: 10.1172/JCI115442
– volume: 46
  start-page: 181
  year: 1991
  ident: 10.1016/j.fsi.2024.109526_bib47
  article-title: Hydrogen peroxide as a mediator of programmed cell death in the blastocyst
  publication-title: Differentiation
  doi: 10.1111/j.1432-0436.1991.tb00880.x
– volume: 21
  year: 2020
  ident: 10.1016/j.fsi.2024.109526_bib25
  article-title: Transcriptome analysis of Paralichthys olivaceus erythrocytes reveals profound immune responses induced by Edwardsiella tarda infection
  publication-title: Int. J. Mol. Sci.
– volume: 77
  start-page: 325
  year: 1981
  ident: 10.1016/j.fsi.2024.109526_bib43
  article-title: Glutathione peroxidase
  publication-title: Methods Enzymol.
  doi: 10.1016/S0076-6879(81)77046-0
– volume: 286
  start-page: 407
  year: 1972
  ident: 10.1016/j.fsi.2024.109526_bib4
  article-title: Oxygen transport in man
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJM197202242860806
– volume: 5
  start-page: 84
  year: 2014
  ident: 10.1016/j.fsi.2024.109526_bib41
  article-title: Red blood cell oxidative stress impairs oxygen delivery and induces red blood cell aging
  publication-title: Front. Physiol.
  doi: 10.3389/fphys.2014.00084
– volume: 24
  start-page: 665
  year: 2002
  ident: 10.1016/j.fsi.2024.109526_bib18
  article-title: Fish immunology. I. Binding and engulfment of Candida albicans by erythrocytes of rainbow trout (Salmo gairdneri Richardson)
  publication-title: Immunopharmacol. Immunotoxicol.
  doi: 10.1081/IPH-120016050
– volume: 35
  start-page: 1215
  year: 2011
  ident: 10.1016/j.fsi.2024.109526_bib33
  article-title: Chemokines in teleost fish species
  publication-title: Dev. Comp. Immunol.
  doi: 10.1016/j.dci.2011.03.011
– volume: 10
  start-page: 1055
  year: 2019
  ident: 10.1016/j.fsi.2024.109526_bib10
  article-title: Fish red blood cells modulate immune genes in response to bacterial inclusion bodies made of TNFα and a G-VHSV fragment
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2019.01055
– volume: 5
  start-page: 415
  year: 2000
  ident: 10.1016/j.fsi.2024.109526_bib49
  article-title: Role of reactive oxygen species (ROS) in apoptosis induction
  publication-title: Apoptosis
  doi: 10.1023/A:1009616228304
– volume: 8
  year: 2019
  ident: 10.1016/j.fsi.2024.109526_bib24
  article-title: Rainbow trout red blood cells exposed to viral hemorrhagic septicemia virus up-regulate antigen-processing mechanisms and MHC I&II, CD86, and CD83 antigen-presenting cell markers
  publication-title: Cells
  doi: 10.3390/cells8050386
– volume: 111
  start-page: S460
  year: 2003
  ident: 10.1016/j.fsi.2024.109526_bib28
  article-title: 2. Cytokines and chemokines
  publication-title: J. Allergy Clin. Immunol.
  doi: 10.1067/mai.2003.108
– volume: 252
  start-page: 38
  year: 1995
  ident: 10.1016/j.fsi.2024.109526_bib44
  article-title: Diversity of glutathione peroxidases
  publication-title: Methods Enzymol.
  doi: 10.1016/0076-6879(95)52007-4
– volume: 126
  start-page: 169
  year: 2013
  ident: 10.1016/j.fsi.2024.109526_bib50
  article-title: Oxidative stress parameters and anti-apoptotic response to hydroxyl radicals in fish erythrocytes: protective effects of glutamine, alanine, citrulline and proline
  publication-title: Aquat. Toxicol.
  doi: 10.1016/j.aquatox.2012.11.005
– volume: 6
  year: 2011
  ident: 10.1016/j.fsi.2024.109526_bib7
  article-title: RNA-Seq reveals an integrated immune response in nucleated erythrocytes
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0026998
– volume: 44
  start-page: 532
  year: 2017
  ident: 10.1016/j.fsi.2024.109526_bib38
  article-title: Antioxidants maintain cellular redox homeostasis by elimination of reactive oxygen species
  publication-title: Cell. Physiol. Biochem.
  doi: 10.1159/000485089
– volume: 6
  start-page: 1968
  year: 2017
  ident: 10.1016/j.fsi.2024.109526_bib22
  article-title: Infectious pancreatic necrosis virus triggers antiviral immune response in rainbow trout red blood cells, despite not being infective
  publication-title: F1000Res
– volume: 2
  start-page: 820
  year: 2004
  ident: 10.1016/j.fsi.2024.109526_bib39
  article-title: Antimicrobial reactive oxygen and nitrogen species: concepts and controversies
  publication-title: Nat. Rev. Microbiol.
  doi: 10.1038/nrmicro1004
– volume: 217
  start-page: 1915
  year: 2018
  ident: 10.1016/j.fsi.2024.109526_bib42
  article-title: Superoxide dismutases: dual roles in controlling ROS damage and regulating ROS signaling
  publication-title: J. Cell Biol.
  doi: 10.1083/jcb.201708007
– volume: 5
  start-page: 36
  year: 2008
  ident: 10.1016/j.fsi.2024.109526_bib20
  article-title: Infectious salmon anaemia virus replication and induction of alpha interferon in Atlantic salmon erythrocytes
  publication-title: Virol. J.
  doi: 10.1186/1743-422X-5-36
– volume: 35
  start-page: 1336
  year: 2011
  ident: 10.1016/j.fsi.2024.109526_bib34
  article-title: The interleukins of fish
  publication-title: Dev. Comp. Immunol.
  doi: 10.1016/j.dci.2011.05.001
– volume: 10
  year: 2021
  ident: 10.1016/j.fsi.2024.109526_bib36
  article-title: Functions of ROS in macrophages and antimicrobial immunity
  publication-title: Antioxidants
  doi: 10.3390/antiox10020313
– volume: 77
  start-page: 164
  year: 2018
  ident: 10.1016/j.fsi.2024.109526_bib16
  article-title: Transcriptome analysis of Pacific white shrimp (Litopenaeus vannamei) challenged by Vibrio parahaemolyticus reveals unique immune-related genes
  publication-title: Fish Shellfish Immunol.
  doi: 10.1016/j.fsi.2018.03.030
– volume: 112
  start-page: 159
  year: 2021
  ident: 10.1016/j.fsi.2024.109526_bib11
  article-title: Escherichia coli induced ferroptosis in red blood cells of grass carp (Ctenopharyngodon idella)
  publication-title: Fish Shellfish Immunol.
  doi: 10.1016/j.fsi.2020.09.036
– volume: 26
  start-page: 239
  year: 1972
  ident: 10.1016/j.fsi.2024.109526_bib45
  article-title: Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
  publication-title: Br. J. Cancer
  doi: 10.1038/bjc.1972.33
– volume: 45
  start-page: 780
  year: 2015
  ident: 10.1016/j.fsi.2024.109526_bib9
  article-title: Transcriptome analyses of Atlantic salmon (Salmo salar L.) erythrocytes infected with piscine orthoreovirus (PRV)
  publication-title: Fish Shellfish Immunol.
  doi: 10.1016/j.fsi.2015.05.049
– volume: 1
  start-page: 468
  year: 2020
  ident: 10.1016/j.fsi.2024.109526_bib3
  article-title: Sustainable aquaculture through the one health lens
  publication-title: Nat. Food
  doi: 10.1038/s43016-020-0127-5
– volume: 532
  start-page: 1
  year: 2021
  ident: 10.1016/j.fsi.2024.109526_bib12
  article-title: Aeromonas hydrophila infection activates death receptor apoptosis pathway in the red blood cells of grass carp (Ctenopharyngodon idellus)
  publication-title: Aquaculture
  doi: 10.1016/j.aquaculture.2020.735956
– volume: 8
  start-page: 813
  year: 2007
  ident: 10.1016/j.fsi.2024.109526_bib35
  article-title: ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis
  publication-title: Nat. Rev. Mol. Cell Biol.
  doi: 10.1038/nrm2256
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Snippet In teleost blood, red blood cells (RBCs) are the most common type of cell, and they differ from mammalian RBCs in having a nucleus and other organelles. As...
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SubjectTerms Aeromonas hydrophila
Aeromonas hydrophila - physiology
Animals
Antioxidant system
Apoptosis
bacterial infections
Carps - genetics
Carps - immunology
catalase
Ctenopharyngodon idella
erythrocytes
Erythrocytes - immunology
Escherichia coli
Escherichia coli - immunology
Escherichia coli - physiology
Escherichia coli Infections - immunology
Escherichia coli Infections - veterinary
fish
Fish Diseases - immunology
Fish Proteins - genetics
Fish Proteins - immunology
flow cytometry
GcRBCs
gene expression
gene expression regulation
genome
glutathione peroxidase
Gram-Negative Bacterial Infections - immunology
Gram-Negative Bacterial Infections - veterinary
immune response
Immunity, Innate - genetics
Inflammation
interleukin-12
interleukin-17
interleukin-4
interleukin-6
interleukin-8
mammals
organelles
reactive oxygen species
ROS
sequence analysis
shellfish
Staphylococcal Infections - immunology
Staphylococcal Infections - veterinary
Staphylococcus aureus
Staphylococcus aureus - immunology
Staphylococcus aureus - physiology
superoxide dismutase
Transcriptome - immunology
transcriptomics
tumor necrosis factors
Title Exploration of the immune response of grass carp (Ctenopharyngodon idellus) erythrocytes during bacterial infection
URI https://dx.doi.org/10.1016/j.fsi.2024.109526
https://www.ncbi.nlm.nih.gov/pubmed/38554743
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https://www.proquest.com/docview/3153592675
Volume 149
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