Induced membrane technique: a critical literature analysis and proposal for a failure classification scheme

The reconstruction of long-bone segmental defects remains challenging, with the three common methods of treatment being bone transport, vascularized bone transfer, and the induced membrane technique (IMT). Because of its simplicity, replicability, and reliability, usage of IMT has spread all over th...

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Published in:European journal of trauma and emergency surgery (Munich : 2007) Vol. 47; no. 5; pp. 1373 - 1380
Main Authors: Mathieu, Laurent, Durand, Marjorie, Collombet, Jean-Marc, de Rousiers, Arnaud, de l’Escalopier, Nicolas, Masquelet, Alain-Charles
Format: Journal Article
Language:English
Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.10.2021
Springer Nature B.V
Springer Verlag
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ISSN:1863-9933, 1863-9941, 1863-9941
Online Access:Get full text
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Summary:The reconstruction of long-bone segmental defects remains challenging, with the three common methods of treatment being bone transport, vascularized bone transfer, and the induced membrane technique (IMT). Because of its simplicity, replicability, and reliability, usage of IMT has spread all over the world in the last decade, with more than 300 papers published in the PubMed literature database on this subject so far. Most of the clinical studies have reported high rates of bone union, yet some also include more controversial results with frequent complications and revision surgeries. At the same time, various experimental research efforts have been designed to understand and improve the biological properties of the induced membrane. This literature review aims to provide an overview of IMT clinical results in terms of bone union and complications and to compare them with those of other reconstructive procedures. In light of our findings, we then propose an original classification scheme of IMT failures distinguishing between preventable and nonpreventable failures.
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ISSN:1863-9933
1863-9941
1863-9941
DOI:10.1007/s00068-020-01540-9