Update on pathomechanisms and treatments in allergic rhinitis

Allergic rhinitis (AR) is a global health problem with increasing prevalence and association with an enormous medical and socioeconomic burden. New recognition of immune cells such as type 2 innate lymphocytes (ILC2s), T helper (Th2) 2 cells, follicular helper T cells, follicular regulatory T cells,...

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Vydáno v:Allergy (Copenhagen) Ročník 77; číslo 11; s. 3309 - 3319
Hlavní autoři: Zhang, Yuan, Lan, Feng, Zhang, Luo
Médium: Journal Article
Jazyk:angličtina
Vydáno: Denmark Blackwell Publishing Ltd 01.11.2022
Témata:
Allergens
Allergic rhinitis
biomarkers
CD4-positive T-lymphocytes
Clinical trials
cost effectiveness
COVID-19
COVID-19 infection
Dendritic cells
Epithelial cells
epithelium
etiology
Hay fever
Humans
immune cells
Immunity, Innate
Immunoglobulin E
Immunoregulation
Immunotherapy
Inflammation
Lymphocytes
Lymphocytes B
Lymphocytes T
mechanisms
mortality
Pandemics
pathogenesis
Public health
Rhinitis
Rhinitis, Allergic - diagnosis
Rhinitis, Allergic - therapy
Risk factors
COVID-19
immune cells
allergic rhinitis
mechanisms
immunotherapy
ISSN:0105-4538, 1398-9995, 1398-9995
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Abstract Allergic rhinitis (AR) is a global health problem with increasing prevalence and association with an enormous medical and socioeconomic burden. New recognition of immune cells such as type 2 innate lymphocytes (ILC2s), T helper (Th2) 2 cells, follicular helper T cells, follicular regulatory T cells, regulatory T cells, B cells, dendritic cells, and epithelial cells in AR pathogenesis has been updated in this review paper. An in‐depth understanding of the mechanisms underlying AR will aid the identification of biomarkers associated with disease and ultimately provide valuable parameters critical to guide personalized targeted therapy. As the only etiological treatment option for AR, allergen‐specific immunotherapy (AIT) has attracted increasing attention, with evidence for effectiveness of AIT recently demonstrated in several randomized controlled trials and long‐term real‐life studies. The exploration of biologics as therapeutic options has only involved anti‐IgE and anti‐type 2 inflammatory agents; however, the cost‐effectiveness of these agents remains to be elucidated precisely. In the midst of the currently on‐going COVID‐19 pandemic, a global life‐threatening disease, although some studies have indicated that AR is not a risk factor for severity and mortality of COVID‐19, this needs to be confirmed in multi‐centre, real‐life studies of AR patients from different parts of the world.
AbstractList Allergic rhinitis (AR) is a global health problem with increasing prevalence and association with an enormous medical and socioeconomic burden. New recognition of immune cells such as type 2 innate lymphocytes (ILC2s), T helper (Th2) 2 cells, follicular helper T cells, follicular regulatory T cells, regulatory T cells, B cells, dendritic cells, and epithelial cells in AR pathogenesis has been updated in this review paper. An in-depth understanding of the mechanisms underlying AR will aid the identification of biomarkers associated with disease and ultimately provide valuable parameters critical to guide personalized targeted therapy. As the only etiological treatment option for AR, allergen-specific immunotherapy (AIT) has attracted increasing attention, with evidence for effectiveness of AIT recently demonstrated in several randomized controlled trials and long-term real-life studies. The exploration of biologics as therapeutic options has only involved anti-IgE and anti-type 2 inflammatory agents; however, the cost-effectiveness of these agents remains to be elucidated precisely. In the midst of the currently on-going COVID-19 pandemic, a global life-threatening disease, although some studies have indicated that AR is not a risk factor for severity and mortality of COVID-19, this needs to be confirmed in multi-centre, real-life studies of AR patients from different parts of the world.
Allergic rhinitis (AR) is a global health problem with increasing prevalence and association with an enormous medical and socioeconomic burden. New recognition of immune cells such as type 2 innate lymphocytes (ILC2s), T helper (Th2) 2 cells, follicular helper T cells, follicular regulatory T cells, regulatory T cells, B cells, dendritic cells, and epithelial cells in AR pathogenesis has been updated in this review paper. An in-depth understanding of the mechanisms underlying AR will aid the identification of biomarkers associated with disease and ultimately provide valuable parameters critical to guide personalized targeted therapy. As the only etiological treatment option for AR, allergen-specific immunotherapy (AIT) has attracted increasing attention, with evidence for effectiveness of AIT recently demonstrated in several randomized controlled trials and long-term real-life studies. The exploration of biologics as therapeutic options has only involved anti-IgE and anti-type 2 inflammatory agents; however, the cost-effectiveness of these agents remains to be elucidated precisely. In the midst of the currently on-going COVID-19 pandemic, a global life-threatening disease, although some studies have indicated that AR is not a risk factor for severity and mortality of COVID-19, this needs to be confirmed in multi-centre, real-life studies of AR patients from different parts of the world.Allergic rhinitis (AR) is a global health problem with increasing prevalence and association with an enormous medical and socioeconomic burden. New recognition of immune cells such as type 2 innate lymphocytes (ILC2s), T helper (Th2) 2 cells, follicular helper T cells, follicular regulatory T cells, regulatory T cells, B cells, dendritic cells, and epithelial cells in AR pathogenesis has been updated in this review paper. An in-depth understanding of the mechanisms underlying AR will aid the identification of biomarkers associated with disease and ultimately provide valuable parameters critical to guide personalized targeted therapy. As the only etiological treatment option for AR, allergen-specific immunotherapy (AIT) has attracted increasing attention, with evidence for effectiveness of AIT recently demonstrated in several randomized controlled trials and long-term real-life studies. The exploration of biologics as therapeutic options has only involved anti-IgE and anti-type 2 inflammatory agents; however, the cost-effectiveness of these agents remains to be elucidated precisely. In the midst of the currently on-going COVID-19 pandemic, a global life-threatening disease, although some studies have indicated that AR is not a risk factor for severity and mortality of COVID-19, this needs to be confirmed in multi-centre, real-life studies of AR patients from different parts of the world.
Author Lan, Feng
Zhang, Yuan
Zhang, Luo
Author_xml – sequence: 1
  givenname: Yuan
  orcidid: 0000-0003-1080-4267
  surname: Zhang
  fullname: Zhang, Yuan
  organization: Beijing TongRen Hospital, Capital Medical University
– sequence: 2
  givenname: Feng
  orcidid: 0000-0002-1709-5179
  surname: Lan
  fullname: Lan, Feng
  email: fenglanent@126.com
  organization: Beijing Institute of Otolaryngology
– sequence: 3
  givenname: Luo
  orcidid: 0000-0002-0910-9884
  surname: Zhang
  fullname: Zhang, Luo
  email: dr.luozhang@139.com
  organization: Beijing TongRen Hospital, Capital Medical University
BackLink https://www.ncbi.nlm.nih.gov/pubmed/35892225$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1126/science.aaw6433
10.1016/j.jaci.2019.02.008
10.1159/000504366
10.1038/s41390-020-01180-0
10.1038/nri.2016.94
10.3389/fimmu.2020.625630
10.1016/j.jaci.2016.03.017
10.1002/lary.29586
10.1001/jama.2019.1113
10.1016/j.anai.2019.11.007
10.2500/aap.2021.42.210028
10.1111/all.15023
10.1111/all.14240
10.1111/all.15042
10.1111/all.15163
10.1002/clt2.12055
10.1016/j.jaip.2020.08.009
10.1097/ACI.0000000000000781
10.1111/all.12461
10.1111/all.14876
10.1002/lary.28433
10.1002/clt2.12065
10.1016/j.jaci.2021.03.030
10.1016/j.anai.2020.05.026
10.4168/aair.2021.13.3.363
10.1111/pai.13332
10.1111/cea.12471
10.1016/j.jaci.2020.07.002
10.15586/aei.v49i2.52
10.1038/s41586-018-0449-8
10.1016/j.lfs.2021.119922
10.1111/all.14180
10.18176/jiaci.0561
10.1111/cea.13891
10.4168/aair.2017.9.3.272
10.1083/jcb.202005093
10.4193/Rhin20.126
10.1111/all.13996
10.1159/000513158
10.12932/AP‐140820‐0941
10.1016/j.jaip.2021.02.013
10.1186/s13601-020-00315-0
10.3390/metabo11090613
10.1002/clt2.12147
10.3389/fimmu.2020.00104
10.1111/all.14434
10.1159/000517152
10.1111/pai.13569
10.1111/all.14452
10.1111/all.15292
10.2217/imt-2020-0232
10.1164/rccm.202011-4107OC
10.1016/j.intimp.2021.108233
10.1038/s41598-021-92561-w
10.1038/s41577-021-00538-7
10.1111/cea.14088
10.1126/sciimmunol.abd8411
10.1126/science.aba0629
10.2147/JAA.S291879
10.1111/all.14612
10.1111/pai.13477
10.1016/j.jaci.2011.11.019
10.1111/imm.13317
10.1002/clt2.12094
10.1111/all.14124
10.2147/JAA.S318892
10.1080/02770903.2021.1971701
10.1111/all.14639
10.1038/nature23676
10.1111/all.13672
10.1016/j.anai.2020.06.038
10.1111/cea.13740
10.1111/all.14581
10.1126/sciimmunol.aay2754
10.1111/all.14264
10.1002/ctm2.717
10.1016/j.waojou.2020.100458
10.1016/j.anai.2020.09.016
10.1038/s41577-020-00477-9
10.1111/all.14288
10.1097/ACI.0000000000000216
10.1016/j.waojou.2021.100558
10.1111/all.13295
10.1016/j.waojou.2021.100540
10.1111/all.14756
10.1016/j.jaci.2021.02.006
10.1111/all.13583
10.1111/all.12878
10.1016/j.jaci.2018.03.008
10.1111/all.14218
10.1007/s11882-020-00920-w
10.1016/j.jaci.2021.02.019
10.1016/j.jaip.2021.06.060
10.1111/all.15107
10.4168/aair.2020.12.4.738
10.3389/fimmu.2021.663626
10.1126/science.aan8546
10.1016/j.intimp.2022.108611
10.1016/S0140-6736(21)01744-X
10.1016/j.jaci.2022.01.012
10.1016/j.alit.2019.07.007
10.1111/all.15259
10.5415/apallergy.2021.11.e43
10.1016/j.immuni.2020.12.013
10.1016/j.jaci.2019.11.046
10.1016/j.jaci.2005.09.036
10.1016/j.jaci.2020.07.036
10.1111/all.14896
10.1111/all.14726
10.1016/j.jaci.2019.04.027
10.1016/j.jaci.2019.11.029
10.1177/19458924211041438
10.1016/j.jaci.2018.12.1018
10.1038/nri.2017.118
10.1177/19458924211050547
10.1002/jcph.2004
10.1016/j.iac.2020.06.001
10.1111/cei.13647
10.1186/s12931-021-01766-0
10.3389/fimmu.2021.805404
10.1111/all.15057
10.1007/s00011-021-01460-3
10.1016/j.jaci.2020.10.029
10.1016/j.jaci.2021.05.039
10.1016/j.lanepe.2021.100275
10.1038/s41385-021-00410-w
10.1111/all.14815
10.1111/all.14858
10.15252/embj.2018100300
10.1016/j.jaci.2020.10.035
10.1111/coa.13651
10.1038/s41572-020-00227-0
10.1007/s40265-020-01406-9
10.1038/nature24029
10.1016/j.jaci.2019.09.010
10.1126/scitranslmed.aam9171
10.1177/19458924211005592
10.1002/clt2.12075
10.1111/all.15279
10.1111/all.14838
10.1016/j.biomaterials.2021.120798
10.1159/000514587
10.1016/j.jaip.2021.10.049
10.1080/1744666X.2021.1968834
10.1111/imr.12937
10.1016/j.jaip.2019.11.030
10.3389/falgy.2021.810133
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ISSN 0105-4538
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IngestDate Fri Jul 11 18:28:40 EDT 2025
Thu Jul 10 18:51:36 EDT 2025
Fri Oct 03 09:51:12 EDT 2025
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Issue 11
Keywords COVID-19
immune cells
allergic rhinitis
mechanisms
immunotherapy
Language English
License 2022 European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd.
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Notes Funding information
(
This work was supported by the program for the Changjiang scholars and innovative research team (IRT13082), the National Natural Science Foundation of China
82071022), Beijing Municipal Science and Technology Project (Z181100001618002) and Beijing Nova Program of Science and Technology (Z191100001119117
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References 2018; 560
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2018; 360
2021; 22
2020; 20
2021; 126
2021; 204
2021; 206
2014; 69
2020; 13
2016; 71
2021; 284
2021; 163
2020; 12
2020; 11
2020; 124
2020; 10
2020; 125
2017; 9
2012; 129
2019; 365
2019; 321
2021; 70
2020; 8
2015; 45
2021; 35
2020; 6
2020; 5
2021; 76
2021; 32
2021; 1‐9
2021; 31
2021; 398
2020; 50
2022; 36
2018; 73
2021; 273
2022; 77
2020; 219
2021; 9
2018; 142
2021; 46
2015; 15
2021; 49
2021; 6
2021; 42
2021; 89
2021; 2
2019; 74
2021; 101
2021; 148
2020; 40
2021; 147
2020; 181
2020; 80
2021; 182
2019; 38
2020; 145
2020; 146
2016; 16
2021; 52
2021; 51
2006; 117
2019; 144
2019; 143
2021; 14
2021; 13
2017; 549
2018; 18
2021; 59
2021; 54
2021; 12
2021; 11
2020; 75
2021; 299
2022; 60
2021
2022; 62
2021; 17
2022; 12
2022; 13
2021; 371
2020; 69
2021; 131
2016; 138
2022; 10
2022; 106
2022; 149
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e_1_2_8_128_1
e_1_2_8_11_1
e_1_2_8_34_1
e_1_2_8_53_1
e_1_2_8_76_1
Hoang MP (e_1_2_8_104_1) 2022; 60
e_1_2_8_101_1
e_1_2_8_124_1
e_1_2_8_147_1
e_1_2_8_30_1
e_1_2_8_72_1
e_1_2_8_29_1
e_1_2_8_25_1
Tsabouri S (e_1_2_8_121_1) 2021; 59
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e_1_2_8_2_1
e_1_2_8_133_1
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e_1_2_8_39_1
e_1_2_8_35_1
e_1_2_8_16_1
Rodrigues J (e_1_2_8_17_1) 2021; 59
e_1_2_8_58_1
e_1_2_8_92_1
e_1_2_8_96_1
e_1_2_8_100_1
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e_1_2_8_73_1
e_1_2_8_123_1
e_1_2_8_50_1
e_1_2_8_146_1
References_xml – volume: 549
  start-page: 351
  issue: 7672
  year: 2017
  end-page: 356
  article-title: The neuropeptide NMU amplifies ILC2‐driven allergic lung inflammation
  publication-title: Nature
– volume: 62
  start-page: 689
  issue: 5
  year: 2022
  end-page: 695
  article-title: Pharmacokinetics and concentration‐response of dupilumab in patients with seasonal allergic rhinitis
  publication-title: J Clin Pharmacol
– volume: 11
  start-page: 613
  issue: 9
  year: 2021
  article-title: Metabolomics reveals process of allergic rhinitis patients with single‐ and double‐species mite subcutaneous immunotherapy
  publication-title: Metabolites
– volume: 22
  start-page: 170
  issue: 1
  year: 2021
  article-title: Intralymphatic immunotherapy with tyrosine‐adsorbed allergens: a double‐blind, placebo‐controlled trial
  publication-title: Respir Res
– volume: 11
  year: 2020
  article-title: B cell‐activating factor promotes B cell survival in ectopic lymphoid tissues in nasal polyps
  publication-title: Front Immunol
– volume: 15
  start-page: 581
  issue: 6
  year: 2015
  end-page: 587
  article-title: Effect of allergen‐specific immunotherapy on CD4+ T cells
  publication-title: Curr Opin Allergy Clin Immunol
– volume: 14
  issue: 5
  year: 2021
  article-title: Naso‐ocular neuropeptide interactions in allergic rhinoconjunctivitis, rhinitis, and conjunctivitis
  publication-title: World Allergy Organ J
– volume: 76
  start-page: 2952
  issue: 10
  year: 2021
  end-page: 2964
  article-title: Management of anaphylaxis due to COVID‐19 vaccines in the elderly
  publication-title: Allergy
– volume: 117
  start-page: 134
  issue: 1
  year: 2006
  end-page: 140
  article-title: Omalizumab pretreatment decreases acute reactions after rush immunotherapy for ragweed‐induced seasonal allergic rhinitis
  publication-title: J Allergy Clin Immunol
– volume: 11
  issue: 4
  year: 2021
  article-title: Efficacy of subcutaneous immunotherapy for patients with asthma and allergic rhinitis in Korea: effect on eosinophilic inflammation
  publication-title: Asia Pac Allergy
– volume: 89
  start-page: 1832
  issue: 7
  year: 2021
  end-page: 1839
  article-title: Intranasal fluticasone furoate in pediatric allergic rhinitis: randomized controlled study
  publication-title: Pediatr Res
– volume: 21
  start-page: 739
  issue: 11
  year: 2021
  end-page: 751
  article-title: Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions?
  publication-title: Nat Rev Immunol
– volume: 144
  start-page: 1242
  issue: 5
  year: 2019
  end-page: 1253
  article-title: Blocking histone deacetylase activity as a novel target for epithelial barrier defects in patients with allergic rhinitis
  publication-title: J Allergy Clin Immunol
– volume: 12
  year: 2021
  article-title: Nasal epithelial barrier integrity and tight junctions disruption in allergic rhinitis: overview and pathogenic insights
  publication-title: Front Immunol
– volume: 74
  start-page: 815
  issue: 4
  year: 2019
  end-page: 818
  article-title: Comparison of regulatory B cells in asthma and allergic rhinitis
  publication-title: Allergy
– volume: 147
  start-page: 1020
  issue: 3
  year: 2021
  end-page: 1030.e1010
  article-title: A 300 IR sublingual tablet is an effective, safe treatment for house dust mite‐induced allergic rhinitis: an international, double‐blind, placebo‐controlled, randomized phase III clinical trial
  publication-title: J Allergy Clin Immunol
– volume: 12
  year: 2021
  article-title: Identification of robust biomarkers for early predicting efficacy of subcutaneous immunotherapy in children with house dust mite‐induced allergic rhinitis by multiple cytokine profiling
  publication-title: Front Immunol
– volume: 8
  start-page: 1465
  issue: 4
  year: 2020
  end-page: 1467
  article-title: Epinephrine‐coated syringe for SCIT reduced local reactions: a randomized, double‐blind, placebo‐controlled trial
  publication-title: J Allergy Clin Immunol Pract
– volume: 124
  start-page: 171
  issue: 2
  year: 2020
  end-page: 178
  article-title: Efficacy and safety of twice‐daily and once‐daily olopatadine‐mometasone combination nasal spray for seasonal allergic rhinitis
  publication-title: Ann Allergy Asthma Immunol
– volume: 76
  start-page: 1624
  issue: 6
  year: 2021
  end-page: 1628
  article-title: ARIA‐EAACI statement on severe allergic reactions to COVID‐19 vaccines ‐ An EAACI‐ARIA Position Paper
  publication-title: Allergy
– volume: 45
  start-page: 384
  issue: 2
  year: 2015
  end-page: 393
  article-title: Elevated presence of myeloid dendritic cells in nasal polyps of patients with chronic rhinosinusitis
  publication-title: Clin Exp Allergy
– volume: 14
  start-page: 1144
  issue: 5
  year: 2021
  end-page: 1159
  article-title: Extrafollicular IgD+ B cells generate IgE antibody secreting cells in the nasal mucosa
  publication-title: Mucosal Immunol
– volume: 12
  issue: 4
  year: 2022
  article-title: Comparative study of novel dosing schedules for interrupted immunotherapy for allergic rhinitis
  publication-title: Clin Transl Allergy
– volume: 77
  start-page: 883
  issue: 3
  year: 2022
  end-page: 896
  article-title: High‐dose pollen intralymphatic immunotherapy: Two RDBPC trials question the benefit of dose increase
  publication-title: Allergy
– volume: 40
  start-page: 539
  issue: 4
  year: 2020
  end-page: 547
  article-title: Biologics for the treatment of allergic rhinitis, chronic rhinosinusitis, and nasal polyposis
  publication-title: Immunol Allergy Clin North Am
– volume: 371
  start-page: 52
  issue: 6524
  year: 2021
  end-page: 57
  article-title: Airway stem cells sense hypoxia and differentiate into protective solitary neuroendocrine cells
  publication-title: Science
– volume: 59
  start-page: 501
  issue: 6
  year: 2021
  end-page: 510
  article-title: Omalizumab for the treatment of allergic rhinitis: a systematic review and meta‐analysis
  publication-title: Rhinology
– volume: 77
  start-page: 1263
  issue: 4
  year: 2022
  end-page: 1273
  article-title: Coordinated IgG2 and IgE responses as a marker of allergen immunotherapy efficacy
  publication-title: Allergy
– volume: 219
  issue: 10
  year: 2020
  article-title: Notch2 complements Notch1 to mediate inductive signaling that initiates early T cell development
  publication-title: J Cell Biol
– volume: 182
  start-page: 631
  issue: 7
  year: 2021
  end-page: 636
  article-title: Subcutaneous allergen immunotherapy in children: real life compliance and effect of COVID‐19 pandemic on compliance
  publication-title: Int Arch Allergy Immunol
– volume: 143
  start-page: 2190
  issue: 6
  year: 2019
  end-page: 2201.e2199
  article-title: Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid
  publication-title: J Allergy Clin Immunol
– volume: 321
  start-page: 946
  issue: 10
  year: 2019
  end-page: 955
  article-title: Effect of epicutaneous immunotherapy vs placebo on reaction to peanut protein ingestion among children with peanut allergy: The PEPITES randomized clinical trial
  publication-title: JAMA
– volume: 52
  start-page: 878
  issue: 7
  year: 2021
  end-page: 887
  article-title: Suppression function against environmental dust exposure after Dermatophagoides pteronyssinus immunotherapy is associated with production of specific and cross‐reactive immunoglobulin G4
  publication-title: Clin Exp Allergy
– volume: 75
  start-page: 2026
  issue: 8
  year: 2020
  end-page: 2036
  article-title: Artemisia annua‐sublingual immunotherapy for seasonal allergic rhinitis: a randomized controlled trial
  publication-title: Allergy
– volume: 125
  start-page: 565
  issue: 5
  year: 2020
  end-page: 576
  article-title: Efficacy of dupilumab on clinical outcomes in patients with asthma and perennial allergic rhinitis
  publication-title: Ann Allergy Asthma Immunol
– volume: 49
  start-page: 31
  issue: 2
  year: 2021
  end-page: 39
  article-title: Aqueous intradermal low‐dose house dust mite immunotherapy in tropical settings: a valid cost‐effective approach for developing nations?
  publication-title: Allergol Immunopathol
– volume: 149
  start-page: 189
  issue: 1
  year: 2022
  end-page: 199
  article-title: Novel antibody cocktail targeting Bet v 1 rapidly and sustainably treats birch allergy symptoms in a phase 1 study
  publication-title: J Allergy Clin Immunol
– volume: 71
  start-page: 1086
  issue: 8
  year: 2016
  end-page: 1094
  article-title: T follicular helper (Tfh ) cells in normal immune responses and in allergic disorders
  publication-title: Allergy
– volume: 38
  start-page: e100300
  issue: 4
  year: 2019
  article-title: Long‐term expanding human airway organoids for disease modeling
  publication-title: EMBO J
– volume: 11
  issue: 6
  year: 2021
  article-title: Efficacy and safety of intralymphatic immunotherapy in allergic rhinitis: a systematic review and meta‐analysis
  publication-title: Clin Transl Allergy
– volume: 6
  start-page: 95
  issue: 1
  year: 2020
  article-title: Allergic rhinitis
  publication-title: Nat Rev Dis Primers
– volume: 17
  start-page: 969
  issue: 9
  year: 2021
  end-page: 975
  article-title: The effect of immunotherapy on cross‐reactivity between house dust mite and other allergens in house dust mite ‐sensitized patients with allergic rhinitis
  publication-title: Expert Rev Clin Immunol
– volume: 11
  start-page: 104
  year: 2020
  article-title: The imbalance of circulating follicular helper T cells and follicular regulatory T cells is associated with disease activity in patients with ulcerative colitis
  publication-title: Front Immunol
– volume: 126
  start-page: 127
  issue: 2
  year: 2021
  end-page: 134
  article-title: Local immunoglobulin production in nasal tissues: A key to pathogenesis in chronic rhinosinusitis with nasal polyps and aspirin‐exacerbated respiratory disease
  publication-title: Ann Allergy Asthma Immunol
– volume: 76
  start-page: 1416
  issue: 5
  year: 2021
  end-page: 1431
  article-title: Stromal cells and B cells orchestrate ectopic lymphoid tissue formation in nasal polyps
  publication-title: Allergy
– volume: 75
  start-page: 2599
  issue: 10
  year: 2020
  end-page: 2612
  article-title: CD23 expression on switched memory B cells bridges T‐B cell interaction in allergic rhinitis
  publication-title: Allergy
– volume: 148
  start-page: 867
  issue: 3
  year: 2021
  end-page: 875 e864
  article-title: Optimal human pathogenic TH2 cell effector function requires local epithelial cytokine signaling
  publication-title: J Allergy Clin Immunol
– volume: 560
  start-page: 649
  issue: 7720
  year: 2018
  end-page: 654
  article-title: Allergic inflammatory memory in human respiratory epithelial progenitor cells
  publication-title: Nature
– volume: 14
  start-page: 361
  year: 2021
  end-page: 369
  article-title: SLAMs negatively regulate IL‐21 production in Tfh‐like cells from allergic rhinitis patients
  publication-title: J Asthma Allergy
– volume: 59
  start-page: 2
  issue: 1
  year: 2021
  end-page: 9
  article-title: Leukotriene receptor antagonist addition to intranasal steroid: systematic review and meta‐analysis
  publication-title: Rhinology
– volume: 10
  start-page: 124
  issue: 1
  year: 2022
  end-page: 133
  article-title: Impact of allergic rhinitis and asthma on COVID‐19 infection, hospitalization, and mortality
  publication-title: J Allergy Clin Immunol Pract
– volume: 16
  start-page: 612
  issue: 10
  year: 2016
  end-page: 625
  article-title: T follicular helper cells in space‐time
  publication-title: Nat Rev Immunol
– volume: 77
  start-page: 454
  issue: 2
  year: 2022
  end-page: 468
  article-title: One hundred and ten years of Allergen Immunotherapy: a journey from empiric observation to evidence
  publication-title: Allergy
– volume: 42
  start-page: 283
  issue: 4
  year: 2021
  end-page: 292
  article-title: Intralymphatic immunotherapy for allergic rhinitis: A systematic review and meta‐analysis
  publication-title: Allergy Asthma Proc
– volume: 18
  start-page: 121
  issue: 2
  year: 2018
  end-page: 133
  article-title: TH2 cell development and function
  publication-title: Nature reviews Immunology
– volume: 77
  start-page: 1450
  year: 2022
  end-page: 1463
  article-title: Epithelial and sensory mechanisms of nasal hyperreactivity
  publication-title: Allergy
– volume: 9
  issue: 401
  year: 2017
  article-title: A phenotypically and functionally distinct human TH2 cell subpopulation is associated with allergic disorders
  publication-title: Sci Transl Med
– volume: 132
  start-page: 499
  issue: 3
  year: 2022
  end-page: 508
  article-title: Subcutaneous versus sublingual immunotherapy for adults with allergic rhinitis: a systematic review with meta‐analyses
  publication-title: Laryngoscope
– volume: 145
  start-page: 610
  issue: 2
  year: 2020
  end-page: 618 e619
  article-title: Persistence of the clinical effect of grass allergen peptide immunotherapy after the second and third grass pollen seasons
  publication-title: J Allergy Clin Immunol
– volume: 70
  start-page: 581
  issue: 5
  year: 2021
  end-page: 589
  article-title: Sublingual immunotherapy for 4 years increased the number of Foxp3(+) Treg cells, which correlated with clinical effects
  publication-title: Inflamm Res
– year: 2021
  article-title: Anxiety and depression in allergic rhinitis patients during COVID‐19 pandemic in Wuhan, China
  publication-title: Asian Pac J Allergy Immunol
– volume: 73
  start-page: 479
  issue: 2
  year: 2018
  end-page: 489
  article-title: Pathogenicity of memory Th2 cells is linked to stage of allergic rhinitis
  publication-title: Allergy
– volume: 129
  start-page: 929
  issue: 4
  year: 2012
  end-page: 934
  article-title: Multiple‐allergen and single‐allergen immunotherapy strategies in polysensitized patients: looking at the published evidence
  publication-title: J Allergy Clin Immunol
– volume: 182
  start-page: 1231
  issue: 12
  year: 2021
  end-page: 1244
  article-title: The IgE blocking activity induced by dermatophagoides pteronyssinus subcutaneous immunotherapy does not correlate with specific IgA but with IgG4 in both serum and saliva
  publication-title: Int Arch Allergy Immunol
– volume: 206
  start-page: 141
  issue: 2
  year: 2021
  end-page: 152
  article-title: Follicular helper and follicular regulatory T cell subset imbalance is associated with higher activated B cells and abnormal autoantibody production in primary anti‐phospholipid syndrome patients
  publication-title: Clin Exp Immunol
– volume: 147
  start-page: 663
  issue: 2
  year: 2021
  end-page: 676
  article-title: Altered chromatin landscape in circulating T follicular helper and regulatory cells following grass pollen subcutaneous and sublingual immunotherapy
  publication-title: J Allergy Clin Immunol
– volume: 5
  issue: 47
  year: 2020
  article-title: Divergent T follicular helper cell requirement for IgA and IgE production to peanut during allergic sensitization
  publication-title: Sci Immunol
– volume: 77
  start-page: 2712
  issue: 9
  year: 2022
  end-page: 2724
  article-title: Sequential class switch recombination to IgE and allergen‐induced accumulation of IgE+ plasmablasts occur in the nasal mucosa of local allergic rhinitis patients
  publication-title: Allergy
– volume: 75
  start-page: 2050
  issue: 8
  year: 2020
  end-page: 2058
  article-title: Real‐world evidence of subcutaneous allergoid immunotherapy in house dust mite‐induced allergic rhinitis and asthma
  publication-title: Allergy
– volume: 69
  start-page: 1162
  issue: 9
  year: 2014
  end-page: 1170
  article-title: Immune regulation by intralymphatic immunotherapy with modular allergen translocation MAT vaccine
  publication-title: Allergy
– volume: 75
  start-page: 2405
  issue: 9
  year: 2020
  end-page: 2408
  article-title: Clinical characteristics of COVID‐19 patients combined with allergy
  publication-title: Allergy
– volume: 9
  start-page: 1851
  issue: 5
  year: 2021
  end-page: 1857
  article-title: Innate and adaptive immunity: ILC2 and Th2 cells in upper and lower airway allergic diseases
  publication-title: J Allergy Clin Immunol Pract
– volume: 11
  start-page: 13157
  issue: 1
  year: 2021
  article-title: Crucial role of stimulator of interferon genes‐dependent signaling in house dust mite extract‐induced IgE production
  publication-title: Sci Rep
– volume: 181
  start-page: 170
  issue: 3
  year: 2020
  end-page: 182
  article-title: The efficacy and safety of epicutaneous immunotherapy for allergic diseases: a systematic review and meta‐analysis
  publication-title: Int Arch Allergy Immunol
– volume: 74
  start-page: 189
  issue: 1
  year: 2019
  end-page: 192
  article-title: Efficacy and safety of subcutaneous immunotherapy with house dust mite for allergic rhinitis: a meta‐analysis of randomized controlled trials
  publication-title: Allergy
– volume: 6
  issue: 59
  year: 2021
  article-title: Developmental bifurcation of human T follicular regulatory cells
  publication-title: Sci Immunol
– volume: 69
  start-page: 104
  issue: 1
  year: 2020
  end-page: 110
  article-title: Safety profile and immunological response of dual sublingual immunotherapy with house dust mite tablet and Japanese cedar pollen tablet
  publication-title: Allergol Int
– volume: 147
  start-page: 2063
  issue: 6
  year: 2021
  end-page: 2066
  article-title: Memory‐type pathogenic TH2 cells and ILC2s in type 2 allergic inflammation
  publication-title: J Allergy Clin Immunol
– volume: 32
  start-page: 1654
  issue: 8
  year: 2021
  end-page: 1662
  article-title: Metabolomics reveals a correlation between hydroxyeicosatetraenoic acids and allergic asthma: evidence from three years' immunotherapy
  publication-title: Pediatr Allergy Immunol
– volume: 77
  start-page: 843
  issue: 3
  year: 2022
  end-page: 855
  article-title: Direct platelet adhesion potentiates group 2 innate lymphoid cell functions
  publication-title: Allergy
– volume: 80
  start-page: 1831
  issue: 17
  year: 2020
  end-page: 1851
  article-title: Efficacy of montelukast in allergic rhinitis treatment: a systematic review and meta‐analysis
  publication-title: Drugs
– volume: 204
  start-page: 23
  issue: 1
  year: 2021
  end-page: 33
  article-title: Passive prophylactic administration with a single dose of anti‐Fel d 1 monoclonal antibodies REGN1908‐1909 in cat allergen‐induced allergic rhinitis: a randomized, double‐blind, placebo‐controlled clinical trial
  publication-title: Am J Respir Crit Care Med
– volume: 163
  start-page: 310
  issue: 3
  year: 2021
  end-page: 322
  article-title: Epithelial cell‐derived CD83 restores immune tolerance in the airway mucosa by inducing regulatory T‐cell differentiation
  publication-title: Immunology
– volume: 46
  start-page: 52
  issue: 1
  year: 2021
  end-page: 59
  article-title: Sublingual immunotherapy vs placebo in the management of grass pollen‐induced allergic rhinitis in adults: A systematic review and meta‐analysis
  publication-title: Clin Otolaryngol
– volume: 76
  start-page: 2827
  issue: 9
  year: 2021
  end-page: 2839
  article-title: An exhausted phenotype of T(H) 2 cells is primed by allergen exposure, but not reinforced by allergen‐specific immunotherapy
  publication-title: Allergy
– volume: 12
  start-page: 738
  issue: 4
  year: 2020
  end-page: 742
  article-title: Management practice of allergic rhinitis in china during the COVID‐19 pandemic
  publication-title: Allergy Asthma Immunol Res
– volume: 21
  start-page: 559
  issue: 6
  year: 2021
  end-page: 568
  article-title: Update on omalizumab in allergen immunotherapy
  publication-title: Curr Opin Allergy Clin Immunol
– volume: 106
  year: 2022
  article-title: Allergen induces CD11c(+) dendritic cell autophagy to aggravate allergic rhinitis through promoting immune imbalance
  publication-title: Int Immunopharmacol
– volume: 142
  start-page: 321
  issue: 1
  year: 2018
  end-page: 324.e310
  article-title: Correlation of allergen‐specific T follicular helper cell counts with specific IgE levels and efficacy of allergen immunotherapy
  publication-title: J Allergy Clin Immunol
– volume: 20
  start-page: 23
  issue: 7
  year: 2020
  article-title: Allergen immunotherapy for local respiratory allergy
  publication-title: Curr Allergy Asthma Rep
– volume: 398
  start-page: 843
  issue: 10303
  year: 2021
  end-page: 855
  article-title: Inhaled budesonide for COVID‐19 in people at high risk of complications in the community in the UK(PRINCIPLE): a randomised, controlled, open‐label, adaptive platform trial
  publication-title: Lancet
– volume: 145
  start-page: 855
  issue: 3
  year: 2020
  end-page: 867
  article-title: Effects of myeloid and plasmacytoid dendritic cells on ILC2s in patients with allergic rhinitis
  publication-title: J Allergy Clin Immunol
– volume: 13
  issue: 9
  year: 2020
  article-title: Artemisia Annua sublingual immunotherapy for seasonal allergic rhinitis: A multicenter, randomized trial
  publication-title: World Allergy Organ J
– volume: 75
  start-page: 1513
  issue: 6
  year: 2020
  end-page: 1516
  article-title: Th2A and Th17 cell frequencies and regulatory markers as follow‐up biomarker candidates for successful multifood oral immunotherapy
  publication-title: Allergy
– volume: 51
  start-page: 1057
  issue: 8
  year: 2021
  end-page: 1068
  article-title: Decrease in CD38(+) TH2A cell frequencies following immunotherapy with house dust mite tablet correlates with humoral responses
  publication-title: Clin Exp Allergy
– volume: 76
  start-page: 456
  issue: 2
  year: 2021
  end-page: 470
  article-title: Roles of follicular helper and regulatory T cells in allergic diseases and allergen immunotherapy
  publication-title: Allergy
– volume: 12
  issue: 1
  year: 2022
  article-title: TFH 2 cells associate with enhanced humoral immunity to SARS‐CoV‐2 inactivated vaccine in patients with allergic rhinitis
  publication-title: Clin Transl Med
– volume: 147
  start-page: 1507
  issue: 4
  year: 2021
  end-page: 1510
  article-title: IL‐10‐producing innate lymphoid cells increased in patients with house dust mite allergic rhinitis following immunotherapy
  publication-title: J Allergy Clin Immunol
– volume: 13
  year: 2022
  article-title: Long‐term real‐world effectiveness of allergy immunotherapy in patients with allergic rhinitis and asthma: Results from the REACT study, a retrospective cohort study
  publication-title: Lancet Reg Health Eur
– volume: 32
  start-page: 963
  issue: 5
  year: 2021
  end-page: 970
  article-title: 'Stay at home': Is it good or not for house dust mite sensitized children with respiratory allergies?
  publication-title: Pediatr Allergy Immunol
– volume: 284
  year: 2021
  article-title: Notch2 suppresses the development of allergic rhinitis by promoting FOXP3 expression and Treg cell differentiation
  publication-title: Life Sci
– volume: 182
  start-page: 553
  issue: 6
  year: 2021
  end-page: 561
  article-title: Subcutaneous allergen‐specific immunotherapy is safe in pediatric patients with allergic rhinitis
  publication-title: Int Arch Allergy Immunol
– volume: 365
  issue: 6456
  year: 2019
  article-title: Identification of a T follicular helper cell subset that drives anaphylactic IgE
  publication-title: Science
– volume: 11
  issue: 9
  year: 2021
  article-title: Effectiveness of mobile health interventions to improve nasal corticosteroid adherence in allergic rhinitis: a systematic review
  publication-title: Clin Transl Allergy
– volume: 14
  issue: 7
  year: 2021
  article-title: Real‐life adherence to subcutaneous immunotherapy: What has changed in the era of the COVID‐19 pandemic
  publication-title: World Allergy Organ J
– volume: 8
  start-page: 3587
  issue: 10
  year: 2020
  end-page: 3589
  article-title: Clinical presentation at the onset of COVID‐19 and allergic rhinoconjunctivitis
  publication-title: J Allergy Clin Immunol Pract
– volume: 11
  issue: 7
  year: 2021
  article-title: Recent advances and developments in COVID‐19 in the context of allergic diseases
  publication-title: Clin Transl Allergy
– volume: 32
  start-page: 86
  issue: 1
  year: 2021
  end-page: 91
  article-title: Compliance, efficacy, and safety of subcutaneous and sublingual immunotherapy in children with allergic rhinitis
  publication-title: Pediatr Allergy Immunol
– volume: 273
  year: 2021
  article-title: A novel therapeutic modality using CRISPR‐engineered dendritic cells to treat allergies
  publication-title: Biomaterials
– volume: 76
  start-page: 1109
  issue: 4
  year: 2021
  end-page: 1122
  article-title: Vitamin A controls the allergic response through T follicular helper cell as well as plasmablast differentiation
  publication-title: Allergy
– volume: 21
  start-page: 347
  issue: 6
  year: 2021
  end-page: 362
  article-title: Regulation of immune responses by the airway epithelial cell landscape
  publication-title: Nat Rev Immunol
– volume: 360
  issue: 6393
  year: 2018
  article-title: Pulmonary neuroendocrine cells amplify allergic asthma responses
  publication-title: Science
– volume: 148
  start-page: 1061
  issue: 4
  year: 2021
  end-page: 1071
  article-title: Differential induction of allergen‐specific IgA responses following timothy grass subcutaneous and sublingual immunotherapy
  publication-title: J Allergy Clin Immunol
– volume: 54
  start-page: 291
  issue: 2
  year: 2021
  end-page: 307 e297
  article-title: Induction of IL‐10‐producing type 2 innate lymphoid cells by allergen immunotherapy is associated with clinical response
  publication-title: Immunity
– volume: 1‐9
  year: 2021
  article-title: Allergen immunotherapy against house dust mites in patients with local allergic rhinitis and asthma
  publication-title: J Asthma
– volume: 101
  issue: Pt B
  year: 2021
  article-title: IL‐33 receptor expression on myeloid and plasmacytoid dendritic cells after allergen challenge in patients with allergic rhinitis
  publication-title: Int Immunopharmacol
– volume: 76
  start-page: 2617
  issue: 8
  year: 2021
  end-page: 2620
  article-title: Role of salivary microbiome in IL‐10 production and efficacy of sublingual immunotherapy
  publication-title: Allergy
– volume: 9
  start-page: 272
  issue: 3
  year: 2017
  end-page: 277
  article-title: A pilot study of intralymphatic immunotherapy for house dust mite, cat, and dog allergies
  publication-title: Allergy Asthma Immunol Res
– volume: 125
  start-page: 589
  issue: 5
  year: 2020
  end-page: 596
  article-title: Intranasal antihistamine is superior to oral H(1) antihistamine as an add‐on therapy to intranasal corticosteroid for treating allergic rhinitis
  publication-title: Ann Allergy Asthma Immunol
– volume: 76
  start-page: 2354
  issue: 8
  year: 2021
  end-page: 2366
  article-title: Differentiation of COVID‐19 signs and symptoms from allergic rhinitis and common cold: an ARIA‐EAACI‐GA(2) LEN consensus
  publication-title: Allergy
– volume: 10
  start-page: 10
  year: 2020
  article-title: Impact on quality of life and safety of sublingual and subcutaneous immunotherapy in children with severe house dust mite and pollen‐associated allergic rhinoconjunctivitis
  publication-title: Clin Transl Allergy
– volume: 12
  issue: 1
  year: 2022
  article-title: Omalizumab is effective in the preseasonal treatment of seasonal allergic rhinitis
  publication-title: Clin Transl Allergy
– volume: 76
  start-page: 1528
  issue: 5
  year: 2021
  end-page: 1538
  article-title: Basophil sensitivity reflects long‐term clinical outcome of subcutaneous immunotherapy in grass pollen‐allergic patients
  publication-title: Allergy
– volume: 13
  start-page: 363
  issue: 3
  year: 2021
  end-page: 374
  article-title: A potential role of group 2 innate lymphoid cells in eosinophilic chronic rhinosinusitis with nasal polyps
  publication-title: Allergy Asthma Immunol Res
– volume: 9
  start-page: 4103
  issue: 11
  year: 2021
  end-page: 4116
  article-title: Disease‐modifying effect of japanese cedar pollen sublingual immunotherapy tablets
  publication-title: J Allergy Clin Immunol Pract
– volume: 149
  start-page: 1691
  year: 2022
  end-page: 1701.e9
  article-title: CD38(+) B cells affect immunotherapy for allergic rhinitis
  publication-title: J Allergy Clin Immunol
– volume: 77
  start-page: 2229
  year: 2022
  end-page: 2233
  article-title: Differentiation of bronchial epithelial spheroids in the presence of IL‐13 recapitulates characteristic features of asthmatic airway epithelia
  publication-title: Allergy
– volume: 131
  start-page: E1054
  issue: 4
  year: 2021
  end-page: e1061
  article-title: A randomized trial of comparing a combination of montelukast and budesonide with budesonide in allergic rhinitis
  publication-title: Laryngoscope
– volume: 35
  start-page: 846
  issue: 6
  year: 2021
  end-page: 853
  article-title: Immunosuppressive regulation of dendritic cells and T cells in allergic rhinitis by semaphorin 3A
  publication-title: Am J Rhinol Allergy
– volume: 146
  start-page: 180
  issue: 1
  year: 2020
  end-page: 191
  article-title: Allergen‐specific IgG(+) memory B cells are temporally linked to IgE memory responses
  publication-title: J Allergy Clin Immunol
– volume: 75
  start-page: 981
  issue: 4
  year: 2020
  end-page: 983
  article-title: Dynamic change of anti‐inflammatory cytokine IL‐35 in allergen immune therapy for Japanese cedar pollinosis
  publication-title: Allergy
– volume: 36
  start-page: 269
  issue: 2
  year: 2022
  end-page: 280
  article-title: Effect of medical therapy in allergic rhinitis: a systematic review and meta‐analysis
  publication-title: Am J Rhinol Allergy
– volume: 31
  start-page: 80
  issue: 1
  year: 2021
  end-page: 83
  article-title: Shortened up‐dosing with 7 injections of subcutaneous allergy immunotherapy (Alutard SQ) is safe and well tolerated
  publication-title: J Investig Allergol Clin Immunol
– volume: 59
  start-page: 360
  issue: 4
  year: 2021
  end-page: 373
  article-title: Anxiety and depression risk in patients with allergic rhinitis: a systematic review and meta‐analysis
  publication-title: Rhinology
– volume: 299
  start-page: 10
  issue: 1
  year: 2021
  end-page: 30
  article-title: B regulatory cells in allergy
  publication-title: Immunol Rev
– volume: 13
  start-page: 227
  issue: 3
  year: 2021
  end-page: 239
  article-title: Safety of semi‐depot house dust mite allergen extract in children and adolescents with allergic rhinitis and asthma
  publication-title: Immunotherapy
– volume: 144
  start-page: 118
  issue: 1
  year: 2019
  end-page: 128
  article-title: Allergen immunotherapy improves defective follicular regulatory T cells in patients with allergic rhinitis
  publication-title: J Allergy Clin Immunol
– volume: 2
  year: 2021
  article-title: Dropouts from sublingual immunotherapy and the transition to subcutaneous immunotherapy in house dust mite‐sensitized allergic rhinitis patients
  publication-title: Front Allergy
– volume: 14
  start-page: 1045
  year: 2021
  end-page: 1063
  article-title: Short‐term subcutaneous allergy immunotherapy and dupilumab are well tolerated in allergic rhinitis: a randomized trial
  publication-title: J Asthma Allergy
– volume: 76
  start-page: 510
  issue: 2
  year: 2021
  end-page: 532
  article-title: Clinical characteristics of 182 pediatric COVID‐19 patients with different severities and allergic status
  publication-title: Allergy
– volume: 549
  start-page: 282
  issue: 7671
  year: 2017
  end-page: 286
  article-title: The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation
  publication-title: Nature
– volume: 75
  start-page: 450
  issue: 2
  year: 2020
  end-page: 453
  article-title: Allergen immunotherapy with the hypoallergenic B‐cell epitope‐based vaccine BM32 modifies IL‐10‐ and IL‐5‐secreting T cells
  publication-title: Allergy
– volume: 36
  start-page: 245
  issue: 2
  year: 2022
  end-page: 252
  article-title: Efficacy and safety of subcutaneous immunotherapy for local allergic rhinitis: a meta‐analysis of randomized controlled trials
  publication-title: Am J Rhinol Allergy
– volume: 77
  start-page: 197
  issue: 1
  year: 2022
  end-page: 206
  article-title: Adherence to subcutaneous immunotherapy with aeroallergens in real‐life practice during the COVID‐19 pandemic
  publication-title: Allergy
– volume: 77
  start-page: 550
  issue: 2
  year: 2022
  end-page: 558
  article-title: miR‐146a enhances regulatory T‐cell differentiation and function in allergic rhinitis by targeting STAT5b
  publication-title: Allergy
– volume: 138
  start-page: 1192
  issue: 4
  year: 2016
  end-page: 1195 e1195
  article-title: Regulatory B cells and T follicular helper cells are reduced in allergic rhinitis
  publication-title: J Allergy Clin Immunol
– volume: 76
  start-page: 2461
  issue: 8
  year: 2021
  end-page: 2474
  article-title: Allergen‐specific immunotherapy induces the suppressive secretoglobin 1A1 in cells of the lower airways
  publication-title: Allergy
– volume: 60
  start-page: 11
  issue: 1
  year: 2022
  end-page: 19
  article-title: Allergen‐specific immunotherapy for local allergic rhinitis: a systematic review and meta‐analysis
  publication-title: Rhinology
– volume: 147
  start-page: 1011
  issue: 3
  year: 2021
  end-page: 1019
  article-title: Intralymphatic immunotherapy improves grass pollen allergic rhinoconjunctivitis: a 3‐year randomized placebo‐controlled trial
  publication-title: J Allergy Clin Immunol
– volume: 50
  start-page: 1352
  issue: 12
  year: 2020
  end-page: 1361
  article-title: Intradermal Phleum pratense allergoid immunotherapy. Double‐blind, randomized, placebo‐controlled trial
  publication-title: Clin Exp Allergy
– ident: e_1_2_8_35_1
  doi: 10.1126/science.aaw6433
– ident: e_1_2_8_87_1
  doi: 10.1016/j.jaci.2019.02.008
– ident: e_1_2_8_118_1
  doi: 10.1159/000504366
– ident: e_1_2_8_128_1
  doi: 10.1038/s41390-020-01180-0
– ident: e_1_2_8_27_1
  doi: 10.1038/nri.2016.94
– ident: e_1_2_8_49_1
  doi: 10.3389/fimmu.2020.625630
– ident: e_1_2_8_52_1
  doi: 10.1016/j.jaci.2016.03.017
– ident: e_1_2_8_102_1
  doi: 10.1002/lary.29586
– ident: e_1_2_8_117_1
  doi: 10.1001/jama.2019.1113
– ident: e_1_2_8_132_1
  doi: 10.1016/j.anai.2019.11.007
– ident: e_1_2_8_107_1
  doi: 10.2500/aap.2021.42.210028
– ident: e_1_2_8_64_1
  doi: 10.1111/all.15023
– ident: e_1_2_8_69_1
  doi: 10.1111/all.14240
– ident: e_1_2_8_108_1
  doi: 10.1111/all.15042
– ident: e_1_2_8_44_1
  doi: 10.1111/all.15163
– ident: e_1_2_8_112_1
  doi: 10.1002/clt2.12055
– ident: e_1_2_8_142_1
  doi: 10.1016/j.jaip.2020.08.009
– ident: e_1_2_8_120_1
  doi: 10.1097/ACI.0000000000000781
– ident: e_1_2_8_110_1
  doi: 10.1111/all.12461
– ident: e_1_2_8_137_1
  doi: 10.1111/all.14876
– ident: e_1_2_8_131_1
  doi: 10.1002/lary.28433
– ident: e_1_2_8_141_1
  doi: 10.1002/clt2.12065
– ident: e_1_2_8_103_1
  doi: 10.1016/j.jaci.2021.03.030
– ident: e_1_2_8_123_1
  doi: 10.1016/j.anai.2020.05.026
– ident: e_1_2_8_5_1
  doi: 10.4168/aair.2021.13.3.363
– ident: e_1_2_8_100_1
  doi: 10.1111/pai.13332
– ident: e_1_2_8_54_1
  doi: 10.1111/cea.12471
– ident: e_1_2_8_109_1
  doi: 10.1016/j.jaci.2020.07.002
– ident: e_1_2_8_114_1
  doi: 10.15586/aei.v49i2.52
– ident: e_1_2_8_61_1
  doi: 10.1038/s41586-018-0449-8
– ident: e_1_2_8_42_1
  doi: 10.1016/j.lfs.2021.119922
– ident: e_1_2_8_21_1
  doi: 10.1111/all.14180
– ident: e_1_2_8_99_1
  doi: 10.18176/jiaci.0561
– ident: e_1_2_8_22_1
  doi: 10.1111/cea.13891
– ident: e_1_2_8_113_1
  doi: 10.4168/aair.2017.9.3.272
– ident: e_1_2_8_41_1
  doi: 10.1083/jcb.202005093
– ident: e_1_2_8_133_1
  doi: 10.4193/Rhin20.126
– ident: e_1_2_8_86_1
  doi: 10.1111/all.13996
– ident: e_1_2_8_71_1
  doi: 10.1159/000513158
– ident: e_1_2_8_18_1
  doi: 10.12932/AP‐140820‐0941
– ident: e_1_2_8_4_1
  doi: 10.1016/j.jaip.2021.02.013
– ident: e_1_2_8_73_1
  doi: 10.1186/s13601-020-00315-0
– ident: e_1_2_8_77_1
  doi: 10.3390/metabo11090613
– ident: e_1_2_8_148_1
  doi: 10.1002/clt2.12147
– ident: e_1_2_8_38_1
  doi: 10.3389/fimmu.2020.00104
– ident: e_1_2_8_3_1
  doi: 10.1111/all.14434
– ident: e_1_2_8_89_1
  doi: 10.1159/000517152
– ident: e_1_2_8_90_1
  doi: 10.1111/pai.13569
– ident: e_1_2_8_139_1
  doi: 10.1111/all.14452
– ident: e_1_2_8_47_1
  doi: 10.1111/all.15292
– ident: e_1_2_8_74_1
  doi: 10.2217/imt-2020-0232
– ident: e_1_2_8_136_1
  doi: 10.1164/rccm.202011-4107OC
– ident: e_1_2_8_57_1
  doi: 10.1016/j.intimp.2021.108233
– ident: e_1_2_8_29_1
  doi: 10.1038/s41598-021-92561-w
– ident: e_1_2_8_59_1
  doi: 10.1038/s41577-021-00538-7
– ident: e_1_2_8_78_1
  doi: 10.1111/cea.14088
– ident: e_1_2_8_36_1
  doi: 10.1126/sciimmunol.abd8411
– ident: e_1_2_8_9_1
  doi: 10.1126/science.aba0629
– ident: e_1_2_8_32_1
  doi: 10.2147/JAA.S291879
– ident: e_1_2_8_50_1
  doi: 10.1111/all.14612
– ident: e_1_2_8_138_1
  doi: 10.1111/pai.13477
– ident: e_1_2_8_76_1
  doi: 10.1016/j.jaci.2011.11.019
– ident: e_1_2_8_43_1
  doi: 10.1111/imm.13317
– ident: e_1_2_8_122_1
  doi: 10.1002/clt2.12094
– ident: e_1_2_8_83_1
  doi: 10.1111/all.14124
– ident: e_1_2_8_124_1
  doi: 10.2147/JAA.S318892
– ident: e_1_2_8_15_1
  doi: 10.1080/02770903.2021.1971701
– ident: e_1_2_8_39_1
  doi: 10.1111/all.14639
– ident: e_1_2_8_12_1
  doi: 10.1038/nature23676
– ident: e_1_2_8_53_1
  doi: 10.1111/all.13672
– ident: e_1_2_8_134_1
  doi: 10.1016/j.anai.2020.06.038
– ident: e_1_2_8_115_1
  doi: 10.1111/cea.13740
– ident: e_1_2_8_28_1
  doi: 10.1111/all.14581
– ident: e_1_2_8_30_1
  doi: 10.1126/sciimmunol.aay2754
– ident: e_1_2_8_96_1
  doi: 10.1111/all.14264
– ident: e_1_2_8_151_1
  doi: 10.1002/ctm2.717
– ident: e_1_2_8_68_1
  doi: 10.1016/j.waojou.2020.100458
– ident: e_1_2_8_48_1
  doi: 10.1016/j.anai.2020.09.016
– ident: e_1_2_8_10_1
  doi: 10.1038/s41577-020-00477-9
– ident: e_1_2_8_40_1
  doi: 10.1111/all.14288
– ident: e_1_2_8_84_1
  doi: 10.1097/ACI.0000000000000216
– ident: e_1_2_8_146_1
  doi: 10.1016/j.waojou.2021.100558
– ident: e_1_2_8_26_1
  doi: 10.1111/all.13295
– ident: e_1_2_8_16_1
  doi: 10.1016/j.waojou.2021.100540
– ident: e_1_2_8_95_1
  doi: 10.1111/all.14756
– ident: e_1_2_8_23_1
  doi: 10.1016/j.jaci.2021.02.006
– ident: e_1_2_8_65_1
  doi: 10.1111/all.13583
– ident: e_1_2_8_31_1
  doi: 10.1111/all.12878
– ident: e_1_2_8_34_1
  doi: 10.1016/j.jaci.2018.03.008
– ident: e_1_2_8_81_1
  doi: 10.1111/all.14218
– ident: e_1_2_8_106_1
  doi: 10.1007/s11882-020-00920-w
– ident: e_1_2_8_25_1
  doi: 10.1016/j.jaci.2021.02.019
– ident: e_1_2_8_79_1
  doi: 10.1016/j.jaip.2021.06.060
– ident: e_1_2_8_91_1
  doi: 10.1111/all.15107
– ident: e_1_2_8_147_1
  doi: 10.4168/aair.2020.12.4.738
– ident: e_1_2_8_94_1
  doi: 10.3389/fimmu.2021.663626
– ident: e_1_2_8_14_1
  doi: 10.1126/science.aan8546
– ident: e_1_2_8_55_1
  doi: 10.1016/j.intimp.2022.108611
– ident: e_1_2_8_144_1
  doi: 10.1016/S0140-6736(21)01744-X
– ident: e_1_2_8_92_1
  doi: 10.1016/j.jaci.2022.01.012
– ident: e_1_2_8_88_1
  doi: 10.1016/j.alit.2019.07.007
– ident: e_1_2_8_11_1
  doi: 10.1111/all.15259
– ident: e_1_2_8_72_1
  doi: 10.5415/apallergy.2021.11.e43
– ident: e_1_2_8_8_1
  doi: 10.1016/j.immuni.2020.12.013
– ident: e_1_2_8_46_1
  doi: 10.1016/j.jaci.2019.11.046
– ident: e_1_2_8_126_1
  doi: 10.1016/j.jaci.2005.09.036
– ident: e_1_2_8_66_1
  doi: 10.1016/j.jaci.2020.07.036
– ident: e_1_2_8_85_1
  doi: 10.1111/all.14896
– ident: e_1_2_8_150_1
  doi: 10.1111/all.14726
– ident: e_1_2_8_60_1
  doi: 10.1016/j.jaci.2019.04.027
– ident: e_1_2_8_6_1
  doi: 10.1016/j.jaci.2019.11.029
– ident: e_1_2_8_127_1
  doi: 10.1177/19458924211041438
– ident: e_1_2_8_19_1
  doi: 10.1016/j.jaci.2018.12.1018
– ident: e_1_2_8_20_1
  doi: 10.1038/nri.2017.118
– ident: e_1_2_8_105_1
  doi: 10.1177/19458924211050547
– ident: e_1_2_8_125_1
  doi: 10.1002/jcph.2004
– ident: e_1_2_8_119_1
  doi: 10.1016/j.iac.2020.06.001
– ident: e_1_2_8_37_1
  doi: 10.1111/cei.13647
– ident: e_1_2_8_111_1
  doi: 10.1186/s12931-021-01766-0
– ident: e_1_2_8_97_1
  doi: 10.3389/fimmu.2021.805404
– ident: e_1_2_8_7_1
  doi: 10.1111/all.15057
– ident: e_1_2_8_82_1
  doi: 10.1007/s00011-021-01460-3
– ident: e_1_2_8_80_1
  doi: 10.1016/j.jaci.2020.10.029
– ident: e_1_2_8_135_1
  doi: 10.1016/j.jaci.2021.05.039
– ident: e_1_2_8_70_1
  doi: 10.1016/j.lanepe.2021.100275
– ident: e_1_2_8_45_1
  doi: 10.1038/s41385-021-00410-w
– volume: 59
  start-page: 360
  issue: 4
  year: 2021
  ident: e_1_2_8_17_1
  article-title: Anxiety and depression risk in patients with allergic rhinitis: a systematic review and meta‐analysis
  publication-title: Rhinology
– ident: e_1_2_8_143_1
  doi: 10.1111/all.14815
– ident: e_1_2_8_93_1
  doi: 10.1111/all.14858
– ident: e_1_2_8_63_1
  doi: 10.15252/embj.2018100300
– ident: e_1_2_8_33_1
  doi: 10.1016/j.jaci.2020.10.035
– ident: e_1_2_8_67_1
  doi: 10.1111/coa.13651
– ident: e_1_2_8_2_1
  doi: 10.1038/s41572-020-00227-0
– ident: e_1_2_8_130_1
  doi: 10.1007/s40265-020-01406-9
– volume: 60
  start-page: 11
  issue: 1
  year: 2022
  ident: e_1_2_8_104_1
  article-title: Allergen‐specific immunotherapy for local allergic rhinitis: a systematic review and meta‐analysis
  publication-title: Rhinology
– ident: e_1_2_8_13_1
  doi: 10.1038/nature24029
– ident: e_1_2_8_116_1
  doi: 10.1016/j.jaci.2019.09.010
– ident: e_1_2_8_24_1
  doi: 10.1126/scitranslmed.aam9171
– ident: e_1_2_8_56_1
  doi: 10.1177/19458924211005592
– ident: e_1_2_8_129_1
  doi: 10.1002/clt2.12075
– ident: e_1_2_8_62_1
  doi: 10.1111/all.15279
– volume: 59
  start-page: 501
  issue: 6
  year: 2021
  ident: e_1_2_8_121_1
  article-title: Omalizumab for the treatment of allergic rhinitis: a systematic review and meta‐analysis
  publication-title: Rhinology
– ident: e_1_2_8_149_1
  doi: 10.1111/all.14838
– ident: e_1_2_8_58_1
  doi: 10.1016/j.biomaterials.2021.120798
– ident: e_1_2_8_145_1
  doi: 10.1159/000514587
– ident: e_1_2_8_140_1
  doi: 10.1016/j.jaip.2021.10.049
– ident: e_1_2_8_75_1
  doi: 10.1080/1744666X.2021.1968834
– ident: e_1_2_8_51_1
  doi: 10.1111/imr.12937
– ident: e_1_2_8_98_1
  doi: 10.1016/j.jaip.2019.11.030
– ident: e_1_2_8_101_1
  doi: 10.3389/falgy.2021.810133
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Snippet Allergic rhinitis (AR) is a global health problem with increasing prevalence and association with an enormous medical and socioeconomic burden. New recognition...
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SubjectTerms Allergens
Allergic rhinitis
biomarkers
CD4-positive T-lymphocytes
Clinical trials
cost effectiveness
COVID-19
COVID-19 infection
Dendritic cells
Epithelial cells
epithelium
etiology
Hay fever
Humans
immune cells
Immunity, Innate
Immunoglobulin E
Immunoregulation
Immunotherapy
Inflammation
Lymphocytes
Lymphocytes B
Lymphocytes T
mechanisms
mortality
Pandemics
pathogenesis
Public health
Rhinitis
Rhinitis, Allergic - diagnosis
Rhinitis, Allergic - therapy
Risk factors
Title Update on pathomechanisms and treatments in allergic rhinitis
URI https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fall.15454
https://www.ncbi.nlm.nih.gov/pubmed/35892225
https://www.proquest.com/docview/2729439463
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Volume 77
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