A proof‐of‐concept study of an automated solution for clinical metagenomic next‐generation sequencing

Aims Metagenomic next‐generation sequencing (mNGS) has been utilized for diagnosing infectious diseases. It is a culture‐free and hypothesis‐free nucleic acid test for diagnosing all pathogens with known genomic sequences, including bacteria, fungi, viruses and parasites. While this technique greatl...

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Bibliographic Details
Published in:	Journal of applied microbiology Vol. 131; no. 2; pp. 1007 - 1016
Main Authors:	Luan, Y., Hu, H., Liu, C., Chen, B., Liu, X., Xu, Y., Luo, X., Chen, J., Ye, B., Huang, F., Wang, J., Duan, C.
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 01.08.2021
Subjects:	Automation Bacteria bioinformatics Contamination Deoxyribonucleic acid diagnosis of infectious diseases DNA DNA sequencing Infectious diseases Libraries metagenomic next‐generation sequencing Metagenomics Microbial contamination microbial detection Microorganisms Nucleic acids Parasites Pathogens PCR‐free library preparation Polymerase chain reaction RNA Workflow diagnosis of infectious diseases PCR-free library preparation metagenomic next-generation sequencing automation
ISSN:	1364-5072, 1365-2672, 1365-2672
Online Access:	Get full text
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