Histologic and Genomic Analysis of Conjunctival SCC in African and American Cohorts Reveal UV Light and HPV Signatures and High Tumor Mutation Burden

Conjunctival squamous cell carcinoma (conjSCC) is more prevalent and aggressive in sub-Saharan African countries compared with the rest of the world. This study aims to compare the genomic, immunophenotypic, and histologic features between patients from the United States and Ethiopia, to identify et...

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Veröffentlicht in:	Investigative ophthalmology & visual science Jg. 65; H. 4; S. 24
Hauptverfasser:	Gleber-Netto, Frederico O., Nagarajan, Priyadharsini, Sagiv, Oded, Pickering, Curtis R., Gross, Neil, Ning, Jing, Yeshi, Melisachew M., Mitku, Yonas, Tetzlaff, Michael T., Esmaeli, Bita
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States The Association for Research in Vision and Ophthalmology 01.04.2024
Schlagworte:	Anatomy and Pathology/Oncology Black People Conjunctiva Genomics Humans Papillomavirus Infections - genetics Ultraviolet Rays
ISSN:	1552-5783, 0146-0404, 1552-5783
Online-Zugang:	Volltext
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