Identification of a phage-derived depolymerase specific for KL64 capsule of Klebsiella pneumoniae and its anti-biofilm effect

The increasing prevalence of Carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a serious threat to global health. Phages and phage-derived enzymes gained increasing attention for controling CRKP infections. In this study, a lytic phage P510 infecting KL64 type K. pneumoniae was isolated and ch...

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Bibliographic Details
Published in:	Virus genes Vol. 57; no. 5; pp. 434 - 442
Main Authors:	Li, Min, Li, Pei, Chen, Long, Guo, Genglin, Xiao, Yuyi, Chen, Liang, Du, Hong, Zhang, Wei
Format:	Journal Article
Language:	English
Published:	New York Springer US 01.10.2021 Springer Nature B.V
Subjects:	Antibiotics Autographiviridae bacteriophages biofilm Biofilms Biomedical and Life Sciences Biomedicine Electron microscopy Genomes Host range Klebsiella pneumoniae Lysis Medical Microbiology Original Paper Phages Plant Sciences Polysaccharides Public health sequence analysis tail Tail fiber protein Virology Bacteriophages Biofilm Carbapenem-resistant Depolymerase Capsular type
ISSN:	0920-8569, 1572-994X, 1572-994X
Online Access:	Get full text
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