Effect of fluoride dentifrices on white spot lesions during orthodontic treatment: A randomized trial
To determine the effect of Clinpro 5000, Clinpro Tooth Crème, and MI-Paste Plus on the formation of white spot lesions in patients undergoing orthodontic treatment. Three prospective groups with 40 patients undergoing orthodontic treatment in each group were evaluated (total recruitment = 120 subjec...
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| Veröffentlicht in: | The Angle orthodontist Jg. 89; H. 3; S. 365 - 371 |
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| Sprache: | Englisch |
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United States
Edward H. Angle Society of Orthodontists
01.05.2019
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| ISSN: | 0003-3219, 1945-7103, 1945-7103 |
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| Abstract | To determine the effect of Clinpro 5000, Clinpro Tooth Crème, and MI-Paste Plus on the formation of white spot lesions in patients undergoing orthodontic treatment.
Three prospective groups with 40 patients undergoing orthodontic treatment in each group were evaluated (total recruitment = 120 subjects). The selected product was brushed on for 2 minutes twice daily for 4 months. Subjects were reviewed for 4 months on a monthly basis. The Enamel Decalcification Index (EDI) was used to determine the number of white spot lesions per surface at each visit.
100 subjects (35 using Clinpro 5000, 32 using Clinpro Tooth Crème, and 33 using MI Paste Plus) completed the study. The data lend strong support for Clinpro 5000 providing superior protection against enamel decalcification when compared to Clinpro Crème, and mixed support when compared to MI Paste Plus.
The use of Clinpro 5000, Clinpro Crème, and MI paste Plus all have a reduction effect on white spot lesions when compared to studies reported previously. Clinpro 5000 has a marginally better effect than the two other test pastes. The results of this study can be used by clinicians when deciding the effectiveness of using fluoride dentifrice products to prevent white spot lesions in their orthodontic practice (ClinicalTrials.gov ID: NCT03440996). |
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| AbstractList | To determine the effect of Clinpro 5000, Clinpro Tooth Crème, and MI-Paste Plus on the formation of white spot lesions in patients undergoing orthodontic treatment.
Three prospective groups with 40 patients undergoing orthodontic treatment in each group were evaluated (total recruitment = 120 subjects). The selected product was brushed on for 2 minutes twice daily for 4 months. Subjects were reviewed for 4 months on a monthly basis. The Enamel Decalcification Index (EDI) was used to determine the number of white spot lesions per surface at each visit.
100 subjects (35 using Clinpro 5000, 32 using Clinpro Tooth Crème, and 33 using MI Paste Plus) completed the study. The data lend strong support for Clinpro 5000 providing superior protection against enamel decalcification when compared to Clinpro Crème, and mixed support when compared to MI Paste Plus.
The use of Clinpro 5000, Clinpro Crème, and MI paste Plus all have a reduction effect on white spot lesions when compared to studies reported previously. Clinpro 5000 has a marginally better effect than the two other test pastes. The results of this study can be used by clinicians when deciding the effectiveness of using fluoride dentifrice products to prevent white spot lesions in their orthodontic practice (ClinicalTrials.gov ID: NCT03440996). To determine the effect of Clinpro 5000, Clinpro Tooth Crème, and MI-Paste Plus on the formation of white spot lesions in patients undergoing orthodontic treatment.OBJECTIVESTo determine the effect of Clinpro 5000, Clinpro Tooth Crème, and MI-Paste Plus on the formation of white spot lesions in patients undergoing orthodontic treatment.Three prospective groups with 40 patients undergoing orthodontic treatment in each group were evaluated (total recruitment = 120 subjects). The selected product was brushed on for 2 minutes twice daily for 4 months. Subjects were reviewed for 4 months on a monthly basis. The Enamel Decalcification Index (EDI) was used to determine the number of white spot lesions per surface at each visit.MATERIALS AND METHODSThree prospective groups with 40 patients undergoing orthodontic treatment in each group were evaluated (total recruitment = 120 subjects). The selected product was brushed on for 2 minutes twice daily for 4 months. Subjects were reviewed for 4 months on a monthly basis. The Enamel Decalcification Index (EDI) was used to determine the number of white spot lesions per surface at each visit.100 subjects (35 using Clinpro 5000, 32 using Clinpro Tooth Crème, and 33 using MI Paste Plus) completed the study. The data lend strong support for Clinpro 5000 providing superior protection against enamel decalcification when compared to Clinpro Crème, and mixed support when compared to MI Paste Plus.RESULTS100 subjects (35 using Clinpro 5000, 32 using Clinpro Tooth Crème, and 33 using MI Paste Plus) completed the study. The data lend strong support for Clinpro 5000 providing superior protection against enamel decalcification when compared to Clinpro Crème, and mixed support when compared to MI Paste Plus.The use of Clinpro 5000, Clinpro Crème, and MI paste Plus all have a reduction effect on white spot lesions when compared to studies reported previously. Clinpro 5000 has a marginally better effect than the two other test pastes. The results of this study can be used by clinicians when deciding the effectiveness of using fluoride dentifrice products to prevent white spot lesions in their orthodontic practice (ClinicalTrials.gov ID: NCT03440996).CONCLUSIONSThe use of Clinpro 5000, Clinpro Crème, and MI paste Plus all have a reduction effect on white spot lesions when compared to studies reported previously. Clinpro 5000 has a marginally better effect than the two other test pastes. The results of this study can be used by clinicians when deciding the effectiveness of using fluoride dentifrice products to prevent white spot lesions in their orthodontic practice (ClinicalTrials.gov ID: NCT03440996). |
| Author | Kau, Chung H. Abou-Kheir, Nadia Palombini, Anna Wang, Jue Christou, Terpsithea |
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| Cites_doi | 10.1016/0889-5406(88)90453-2 10.1016/j.ajodo.2015.07.039 10.1016/0889-5406(87)90293-9 10.4103/0970-4388.112403 10.1179/bjo.23.1.43 10.1177/0022034509347168 10.4041/kjod.2014.44.3.113 10.1038/sj.ebd.6400899 10.1016/j.ajodo.2010.10.025 10.1093/ejo/8.4.229 10.4103/0972-0707.108185 10.1093/ejo/16.1.19 10.1016/j.ajodo.2007.10.024 10.1186/s40510-015-0095-8 10.1186/s40510-016-0138-9 10.17796/1053-4628-40.4.274 10.1067/mod.2001.114644 10.1016/j.ajodo.2010.04.034 |
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| Keywords | Dental caries Toothpastes Enamel decalcification Fluorides Tooth demineralization Randomized controlled trial |
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| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Undefined-3 Assistant Professor, Department of Orthodontics, School of Dentistry, Univeristy of Alabama at Birmingham, Birmingham, Ala, USA. Former Orthodontic Resident, Department of Orthodontics, School of Dentistry, Univeristy of Alabama at Birmingham, Birmingham, Ala, USA. Professor and Chairman, Department of Orthodontics, School of Dentistry, Univeristy of Alabama at Birmingham, Birmingham, Ala, USA. Orthodontic Resident, Department of Orthodontics, School of Dentistry, Univeristy of Alabama at Birmingham, Birmingham, Ala, USA. |
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| SubjectTerms | Cariostatic Agents Dental Caries - prevention & control Dentifrices - therapeutic use Fluorides Humans Original Prospective Studies Tooth Movement Techniques Tooth Remineralization |
| Title | Effect of fluoride dentifrices on white spot lesions during orthodontic treatment: A randomized trial |
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