Prolonged ventricular asystole: a rare adverse effect of hydrocodone use

Prolonged ventricular asystole is a rare vagal reaction caused by hydrocodone use. Sinus bradycardia is a characteristic presentation of the vasovagal response; examples of other presentations include arrest or atrioventricular block. Physicians need to be aware of ventricular asystole due to vagall...

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Bibliographic Details
Published in:The American journal of case reports Vol. 15; p. 450
Main Authors: Sudhakaran, Sivakumar, Surani, Saherish S, Surani, Salim R
Format: Journal Article
Language:English
Published: United States 21.10.2014
Subjects:
Analgesics, Opioid - adverse effects
Analgesics, Opioid - therapeutic use
Electrocardiography
Female
Heart Arrest - chemically induced
Heart Arrest - diagnosis
Heart Ventricles - drug effects
Heart Ventricles - physiopathology
Humans
Hydrocodone - adverse effects
Hydrocodone - therapeutic use
Middle Aged
Syncope, Vasovagal - chemically induced
Syncope, Vasovagal - diagnosis
Syncope, Vasovagal - physiopathology
ISSN:1941-5923, 1941-5923
Online Access:Get more information
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Summary:Prolonged ventricular asystole is a rare vagal reaction caused by hydrocodone use. Sinus bradycardia is a characteristic presentation of the vasovagal response; examples of other presentations include arrest or atrioventricular block. Physicians need to be aware of ventricular asystole due to vagally-mediated atrioventricular block caused by hydrocodone or other opiates. We present a case of prolonged ventricular asystole in a young patient due to a vasovagal reaction caused by the hydrocodone found in the hydrocodone/acetaminophen combination. Ventricular asystole can be a rare complication of hydrocodone found in hydrocodone/acetaminophen. Physicians need to be aware of this adverse effect, rather then resorting to expensive diagnostic interventions.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
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ISSN:1941-5923
1941-5923
DOI:10.12659/AJCR.891214