Natural killer T cells in families of patients with systemic lupus erythematosus: Their possible role in regulation of IGG production

Objective To determine whether there is a link between the frequency of natural killer T (NKT) cells and high levels of IgG in patients with systemic lupus erythematosus (SLE) and their relatives. Methods Blood samples were obtained from patients with SLE, their first‐degree relatives, patients with...

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Bibliographic Details
Published in:	Arthritis and rheumatism Vol. 56; no. 1; pp. 303 - 310
Main Authors:	Green, Matthew R. J., Kennell, Amy S. M., Larche, Maggie J., Seifert, Martin H., Isenberg, David A., Salaman, Myer R.
Format:	Journal Article
Language:	English
Published:	Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.01.2007 Wiley
Subjects:	Antibodies, Antinuclear - blood Biological and medical sciences CD56 Antigen - biosynthesis CD56 Antigen - immunology Diseases of the osteoarticular system Family Health Female Health Status Humans Immunoglobulin G - biosynthesis Immunoglobulin G - blood Immunoglobulin M - biosynthesis Immunoglobulin M - blood Inflammatory joint diseases Killer Cells, Natural - immunology Killer Cells, Natural - pathology Lupus Erythematosus, Systemic - genetics Lupus Erythematosus, Systemic - immunology Lupus Erythematosus, Systemic - physiopathology Lymphocyte Count Male Medical sciences Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Severity of Illness Index T-Lymphocyte Subsets - immunology T-Lymphocyte Subsets - pathology Human Immunopathology Connective tissue disease Skin disease Family study Diseases of the osteoarticular system IgG Autoimmune disease Inflammatory joint disease Natural killer cell Chronic Systemic lupus erythematosus Treatment Rheumatoid arthritis Systemic disease Production
ISSN:	0004-3591, 1529-0131
Online Access:	Get full text
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