Do preventive interventions for children of mentally ill parents work? Results of a systematic review and meta-analysis
The transgenerational transmission of mental disorders is one of the most significant causes of psychiatric morbidity. Several risk factors for children of parents with mental illness (COPMI) have been identified in numerous studies and meta-analyses. Many interventions have been developed for this...
Uložené v:
| Vydané v: | Current opinion in psychiatry Ročník 30; číslo 4; s. 283 |
|---|---|
| Hlavní autori: | , , , |
| Médium: | Journal Article |
| Jazyk: | English |
| Vydavateľské údaje: |
United States
01.07.2017
|
| Predmet: | |
| ISSN: | 1473-6578, 1473-6578 |
| On-line prístup: | Zistit podrobnosti o prístupe |
| Tagy: |
Pridať tag
Žiadne tagy, Buďte prvý, kto otaguje tento záznam!
|
| Abstract | The transgenerational transmission of mental disorders is one of the most significant causes of psychiatric morbidity. Several risk factors for children of parents with mental illness (COPMI) have been identified in numerous studies and meta-analyses.
Many interventions have been developed for this high-risk group, but data about their efficacy are heterogeneous.
The current meta-analysis reports on 96 articles including 50 independent samples from randomized controlled trials quantifying effects of preventive interventions for COPMI. Random effect models resulted in small, though significant Effect Sizes (ES) for programs enhancing the mother-infant interaction (ES = 0.26) as well as mothers' (ES = 0.33) and children's (ES = 0.31) behavior that proved to be stable over the 12-month follow-up, except for infants' behavior. Interventions for children/adolescents resulted in significant small effects for global psychopathology (ES = 0.13), as well as internalizing symptoms (ES = 0.17), and increased significantly over time, with externalizing symptoms reaching significance in the follow-up assessments as well (ES = 0.17). Interventions addressing parents and children jointly produced overall larger effects. Higher study quality was associated with smaller effects. There is a dearth of high quality studies that effectively reduce the high risk of COPMI for the development of mental disorders. |
|---|---|
| AbstractList | The transgenerational transmission of mental disorders is one of the most significant causes of psychiatric morbidity. Several risk factors for children of parents with mental illness (COPMI) have been identified in numerous studies and meta-analyses.
Many interventions have been developed for this high-risk group, but data about their efficacy are heterogeneous.
The current meta-analysis reports on 96 articles including 50 independent samples from randomized controlled trials quantifying effects of preventive interventions for COPMI. Random effect models resulted in small, though significant Effect Sizes (ES) for programs enhancing the mother-infant interaction (ES = 0.26) as well as mothers' (ES = 0.33) and children's (ES = 0.31) behavior that proved to be stable over the 12-month follow-up, except for infants' behavior. Interventions for children/adolescents resulted in significant small effects for global psychopathology (ES = 0.13), as well as internalizing symptoms (ES = 0.17), and increased significantly over time, with externalizing symptoms reaching significance in the follow-up assessments as well (ES = 0.17). Interventions addressing parents and children jointly produced overall larger effects. Higher study quality was associated with smaller effects. There is a dearth of high quality studies that effectively reduce the high risk of COPMI for the development of mental disorders. The transgenerational transmission of mental disorders is one of the most significant causes of psychiatric morbidity. Several risk factors for children of parents with mental illness (COPMI) have been identified in numerous studies and meta-analyses.PURPOSE OF REVIEWThe transgenerational transmission of mental disorders is one of the most significant causes of psychiatric morbidity. Several risk factors for children of parents with mental illness (COPMI) have been identified in numerous studies and meta-analyses.Many interventions have been developed for this high-risk group, but data about their efficacy are heterogeneous.RECENT FINDINGSMany interventions have been developed for this high-risk group, but data about their efficacy are heterogeneous.The current meta-analysis reports on 96 articles including 50 independent samples from randomized controlled trials quantifying effects of preventive interventions for COPMI. Random effect models resulted in small, though significant Effect Sizes (ES) for programs enhancing the mother-infant interaction (ES = 0.26) as well as mothers' (ES = 0.33) and children's (ES = 0.31) behavior that proved to be stable over the 12-month follow-up, except for infants' behavior. Interventions for children/adolescents resulted in significant small effects for global psychopathology (ES = 0.13), as well as internalizing symptoms (ES = 0.17), and increased significantly over time, with externalizing symptoms reaching significance in the follow-up assessments as well (ES = 0.17). Interventions addressing parents and children jointly produced overall larger effects. Higher study quality was associated with smaller effects. There is a dearth of high quality studies that effectively reduce the high risk of COPMI for the development of mental disorders.SUMMARYThe current meta-analysis reports on 96 articles including 50 independent samples from randomized controlled trials quantifying effects of preventive interventions for COPMI. Random effect models resulted in small, though significant Effect Sizes (ES) for programs enhancing the mother-infant interaction (ES = 0.26) as well as mothers' (ES = 0.33) and children's (ES = 0.31) behavior that proved to be stable over the 12-month follow-up, except for infants' behavior. Interventions for children/adolescents resulted in significant small effects for global psychopathology (ES = 0.13), as well as internalizing symptoms (ES = 0.17), and increased significantly over time, with externalizing symptoms reaching significance in the follow-up assessments as well (ES = 0.17). Interventions addressing parents and children jointly produced overall larger effects. Higher study quality was associated with smaller effects. There is a dearth of high quality studies that effectively reduce the high risk of COPMI for the development of mental disorders. |
| Author | Thanhäuser, Martina de Girolamo, Giovanni Christiansen, Hanna Lemmer, Gunnar |
| Author_xml | – sequence: 1 givenname: Martina surname: Thanhäuser fullname: Thanhäuser, Martina organization: aDepartment of Psychology, Clinical Child and Adolescent Psychology bDepartment of Psychology, Psychological Methods and Social Psychology, Philipps University Marburg, Marburg, Germany cSt. John of God Clinical Research Centre, Brescia, Italy – sequence: 2 givenname: Gunnar surname: Lemmer fullname: Lemmer, Gunnar – sequence: 3 givenname: Giovanni surname: de Girolamo fullname: de Girolamo, Giovanni – sequence: 4 givenname: Hanna surname: Christiansen fullname: Christiansen, Hanna |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/28505032$$D View this record in MEDLINE/PubMed |
| BookMark | eNpNkEtLAzEUhYNUbK3-A5Es3UzNYx7JSqQ-oVAQXbgaMpkEo5mkJjMt8-8NWqF3c--597tncU7BxHmnALjAaIERr67fl-sFOiyakyMww3lFs7Ko2ORgnoLTGD8Tk2PCT8CUsAIViJIZ2N15uAlqq1xvtgoa16vwK7yLUPsA5YexbVAOeg27dBDWjtBYCzcibfsIdz583cAXFQebVKIEjGPsVSd6I2GyNmoHhWvTdy8y4YQdo4ln4FgLG9X5vs_B28P96_IpW60fn5e3q0xSlpMsJ1Jg3FYMEcJbzVjDOaFSo6bQjGtRyjYhWmumFSUpgZwgXOqqkbJCvORkDq7-fDfBfw8q9nVnolTWCqf8EGvMOM8xZZQm9HKPDk2n2noTTCfCWP-HRX4AcdtwUQ |
| CitedBy_id | crossref_primary_10_1017_S2045796018000148 crossref_primary_10_1186_s12913_020_05184_8 crossref_primary_10_1007_s11553_020_00818_5 crossref_primary_10_3389_fpsyt_2019_00305 crossref_primary_10_1016_j_jaacop_2024_06_008 crossref_primary_10_1016_j_jadohealth_2019_11_309 crossref_primary_10_1080_18387357_2023_2220437 crossref_primary_10_1186_s40814_023_01260_y crossref_primary_10_3390_ijerph16071278 crossref_primary_10_1186_s13034_023_00693_w crossref_primary_10_1080_0312407X_2018_1515964 crossref_primary_10_1007_s00278_021_00550_1 crossref_primary_10_1007_s00787_024_02380_3 crossref_primary_10_3389_fpsyg_2021_705400 crossref_primary_10_3389_fpsyt_2024_1376627 crossref_primary_10_3389_fpsyt_2022_778236 crossref_primary_10_1111_jan_13561 crossref_primary_10_2478_sjcapp_2022_0013 crossref_primary_10_1186_s13063_019_3191_0 crossref_primary_10_1038_s44220_024_00285_3 crossref_primary_10_1080_20008066_2025_2468039 crossref_primary_10_1016_j_cpr_2017_11_009 crossref_primary_10_1186_s13063_022_06512_5 crossref_primary_10_1186_s13643_024_02697_9 crossref_primary_10_1136_bmjment_2025_301613 crossref_primary_10_3389_fpsyt_2018_00728 crossref_primary_10_1186_s12888_023_04548_8 crossref_primary_10_3389_fpsyt_2018_00724 crossref_primary_10_3389_fpsyt_2019_00233 crossref_primary_10_7202_1088631ar crossref_primary_10_3389_fpsyt_2019_00155 crossref_primary_10_1017_S0033291721003366 crossref_primary_10_1111_inm_13385 crossref_primary_10_3389_fpsyt_2024_1377100 crossref_primary_10_1007_s10567_021_00355_3 crossref_primary_10_1007_s10826_019_01469_7 crossref_primary_10_1016_j_aprim_2024_103126 crossref_primary_10_1111_cfs_12909 crossref_primary_10_1177_1744629520953765 crossref_primary_10_1136_bmjopen_2024_084080 crossref_primary_10_1016_j_cpr_2025_102569 crossref_primary_10_1007_s11920_022_01367_8 crossref_primary_10_1016_j_mhp_2025_200415 crossref_primary_10_1080_02813432_2021_1928835 crossref_primary_10_3390_soc11030108 crossref_primary_10_1002_cl2_1146 crossref_primary_10_1016_j_jval_2022_11_016 crossref_primary_10_1177_14034948211045462 crossref_primary_10_1186_s12888_022_04349_5 crossref_primary_10_3389_fpsyt_2022_815873 crossref_primary_10_3389_fpsyt_2021_741225 crossref_primary_10_3389_fpsyt_2023_1302474 crossref_primary_10_3389_fpsyt_2019_00606 crossref_primary_10_3389_fpsyt_2024_1287378 crossref_primary_10_1111_infa_12584 crossref_primary_10_1016_j_jad_2023_10_005 crossref_primary_10_1111_bjc_12277 crossref_primary_10_3389_fpsyt_2021_806884 crossref_primary_10_1002_jad_12153 crossref_primary_10_1186_s13034_021_00360_y crossref_primary_10_3389_fpsyt_2022_807251 crossref_primary_10_1371_journal_pone_0233696 crossref_primary_10_3389_fpsyt_2022_781332 crossref_primary_10_3389_fpsyt_2021_815526 crossref_primary_10_1177_10748407211067308 crossref_primary_10_3389_fpsyt_2019_00054 crossref_primary_10_1111_inm_13078 crossref_primary_10_1177_13674935221095648 crossref_primary_10_7202_1109836ar crossref_primary_10_1002_imhj_70007 crossref_primary_10_1111_jmft_12664 crossref_primary_10_1186_s12889_024_20531_8 crossref_primary_10_1016_j_cpr_2020_101955 crossref_primary_10_1186_s12875_023_02145_y crossref_primary_10_1007_s10566_021_09668_4 crossref_primary_10_3389_fpsyt_2021_784022 crossref_primary_10_1111_eip_13194 crossref_primary_10_1371_journal_pone_0251720 crossref_primary_10_1136_bmjopen_2019_033637 crossref_primary_10_1002_cpp_2850 crossref_primary_10_1007_s00115_019_0674_x crossref_primary_10_3389_fpubh_2024_1427432 crossref_primary_10_1111_jpm_12617 crossref_primary_10_1177_15248380231153867 crossref_primary_10_3389_fpsyt_2020_566683 crossref_primary_10_3389_fpsyt_2020_561790 crossref_primary_10_3389_fpsyt_2024_1351629 crossref_primary_10_1016_j_jad_2024_01_027 crossref_primary_10_1186_s12888_023_04530_4 crossref_primary_10_1016_j_chiabu_2024_106867 crossref_primary_10_1111_inm_13324 crossref_primary_10_3389_fdgth_2025_1526995 crossref_primary_10_3389_fpsyt_2024_1380001 crossref_primary_10_1080_02813432_2025_2482037 crossref_primary_10_3389_fpsyg_2023_1104386 |
| ContentType | Journal Article |
| DBID | CGR CUY CVF ECM EIF NPM 7X8 |
| DOI | 10.1097/YCO.0000000000000342 |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | no_fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1473-6578 |
| ExternalDocumentID | 28505032 |
| Genre | Meta-Analysis Systematic Review Journal Article |
| GroupedDBID | --- .-D .3C .Z2 0R~ 4Q1 4Q2 4Q3 53G 5GY 5RE 5VS 6PF 71W 8L- AAAAV AAHPQ AAIQE AARTV AASCR AAWTL AAYEP ABASU ABBUW ABDIG ABIVO ABJNI ABPXF ABVCZ ABXVJ ABZAD ABZZY ACDDN ACEWG ACGFO ACGFS ACHQT ACILI ACNWC ACPRK ACWDW ACWRI ACXJB ACXNZ ADFPA ADGGA ADHPY ADNKB AE3 AE6 AEETU AENEX AETEA AFBFQ AFDTB AFUWQ AHMBA AHQNM AHRYX AHVBC AINUH AJCLO AJIOK AJNWD AJNYG AJZMW AKCTQ ALKUP ALMA_UNASSIGNED_HOLDINGS ALMTX AMJPA AMKUR AMNEI AOHHW AOQMC BQLVK BS7 BYPQX C45 CAG CGR COF CS3 CUY CVF DIWNM DU5 DUNZO E.X EBS ECM EEVPB EIF EJD EX3 F2K F2L F5P FCALG FL- GNXGY GQDEL H0~ HLJTE HZ~ IKREB IN~ IPNFZ J5H JF9 JG8 JK3 JK8 K8S KD2 L-C N9A NPM N~M O9- OAG OAH OCUKA ODA OLC OLG OMH OML OPUJH OPX ORVUJ OUVQU OVD OVDNE OWU OWV OWW OWX OWY OWZ OXXIT P-K P2P PQQKQ R58 RIG RLZ S4R S4S T8P TEORI TSPGW V2I VVN W3M WOQ WOW X3V X3W XXN XYM YFH ZFV ZZMQN 7X8 ADKSD |
| ID | FETCH-LOGICAL-c3842-42ca11d780229df88b9923cf0b5f89fa6cd42cfff8fe3234242016f7bcc709692 |
| IEDL.DBID | 7X8 |
| ISICitedReferencesCount | 109 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000402559900009&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1473-6578 |
| IngestDate | Mon Sep 08 11:58:31 EDT 2025 Tue Jun 24 01:31:40 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 4 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c3842-42ca11d780229df88b9923cf0b5f89fa6cd42cfff8fe3234242016f7bcc709692 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 ObjectType-Undefined-4 |
| PMID | 28505032 |
| PQID | 1899413833 |
| PQPubID | 23479 |
| ParticipantIDs | proquest_miscellaneous_1899413833 pubmed_primary_28505032 |
| PublicationCentury | 2000 |
| PublicationDate | 2017-07-01 |
| PublicationDateYYYYMMDD | 2017-07-01 |
| PublicationDate_xml | – month: 07 year: 2017 text: 2017-07-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Current opinion in psychiatry |
| PublicationTitleAlternate | Curr Opin Psychiatry |
| PublicationYear | 2017 |
| SSID | ssj0004129 |
| Score | 2.4951057 |
| SecondaryResourceType | review_article |
| Snippet | The transgenerational transmission of mental disorders is one of the most significant causes of psychiatric morbidity. Several risk factors for children of... |
| SourceID | proquest pubmed |
| SourceType | Aggregation Database Index Database |
| StartPage | 283 |
| SubjectTerms | Adolescent Child Child of Impaired Parents - psychology Female Humans Mental Disorders - prevention & control Mental Disorders - psychology Parents - psychology Risk Factors |
| Title | Do preventive interventions for children of mentally ill parents work? Results of a systematic review and meta-analysis |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/28505032 https://www.proquest.com/docview/1899413833 |
| Volume | 30 |
| WOSCitedRecordID | wos000402559900009&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1bS8MwFA7qRHzxfpk3Ivha1qbpmjwNmQ5fNocozKeS5gKD0k67Tfz3nrQp24sg2IeWQgLl5DT5TvKd7yB0F6tUgO0tiUExCFC473HWTT1NaCoUkYopUxWbiEcjNpnwsdtwKx2tspkTq4laFdLukXcCCAxgwmVh2Jt9eLZqlD1ddSU0NlErBChjvTqerKmFB1WVsoDGoaV4sCZ1jsed9_5zLV3YXKEt1v4byKwWm8H-fz_zAO05mInva784RBs6P0I7Q3eQfoy-Hgo8c-pNS42na8zHEgOOxU2SNy4MrvX_s288zTJsGev5vMSW0NXDL7pcZPAGrQReqULjOiMGi1xB77nwhNM-OUFvg8fX_pPnajB4MmSUeJRIEQQqthm5XBnGUg6QUBo_jQzjRnSlgibGGGZ0SMCIFBBF18SplDFER5ycoq28yPU5wjRQERMQQgmAnL6Eh681SVNOfeFHmrbRbWPSBHzcHlyIXBeLMlkZtY3O6nFJZrUYR0JYZCVtyMUfel-iXWJX5Ypte4VaBv5wfY225XI-LT9vKueB-2g8_AHDcs-m |
| linkProvider | ProQuest |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Do+preventive+interventions+for+children+of+mentally+ill+parents+work%3F+Results+of+a+systematic+review+and+meta-analysis&rft.jtitle=Current+opinion+in+psychiatry&rft.au=Thanh%C3%A4user%2C+Martina&rft.au=Lemmer%2C+Gunnar&rft.au=de+Girolamo%2C+Giovanni&rft.au=Christiansen%2C+Hanna&rft.date=2017-07-01&rft.issn=1473-6578&rft.eissn=1473-6578&rft.volume=30&rft.issue=4&rft.spage=283&rft_id=info:doi/10.1097%2FYCO.0000000000000342&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1473-6578&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1473-6578&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1473-6578&client=summon |