Morphometric Similarity Patterning of Amyloid-β and Tau Proteins Correlates with Transcriptomics in the Alzheimer’s Disease Continuum

Bridging the gap between cortical morphometric remodeling and gene expression can help to clarify the effects of the selective brain accumulation of Amyloid-β (Aβ) and tau proteins occurring in the Alzheimer’s disease (AD). To this aim, we derived morphometric similarity (MS) networks from 126 Aβ- a...

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Vydané v:	International journal of molecular sciences Ročník 25; číslo 23; s. 12871
Hlavní autori:	Brusini, Lorenza, Dolci, Giorgio, Pini, Lorenzo, Cruciani, Federica, Pizzagalli, Fabrizio, Provero, Paolo, Menegaz, Gloria, Boscolo Galazzo, Ilaria
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Switzerland MDPI AG 01.12.2024
Predmet:	Advertising executives Aged Aged, 80 and over Alzheimer Disease - genetics Alzheimer Disease - metabolism Alzheimer Disease - pathology Alzheimer's disease Amyloid beta-Peptides - genetics Amyloid beta-Peptides - metabolism Brain Brain - metabolism Brain - pathology Development and progression Diseases Female Gene expression Gene Expression Profiling Genes Genetic aspects Genomics Humans Italy Kinases Magnetic resonance imaging Male Proteins tau Proteins - genetics tau Proteins - metabolism Tissues Transcriptome Italy ADNI diffusion MRI T1-weighted MRI partial least squares gene expression enrichment analysis
ISSN:	1422-0067, 1661-6596, 1422-0067
On-line prístup:	Získať plný text
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