MRI in liver cirrhosis

Liver magnetic resonance imaging (MRI) has seen a massive increase in its use over the last decades. Since its first description in the early 1980s, contrast‐enhanced MRI is now the gold standard for the diagnosis of hepatocellular cancer in patients with liver cirrhosis. Techniques like magnetic re...

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Bibliographic Details
Published in:Portal hypertension & cirrhosis (Print) Vol. 1; no. 1; pp. 23 - 41
Main Authors: Alzoubi, Osama, Arar, Ahmad, Singh, Viraj, Erturk, Sukru M., Mozes, Ferenc, Pavlides, Michael
Format: Journal Article
Language:English
Published: Nanjing John Wiley & Sons, Inc 01.06.2022
School of Medicine, The University of Jordan, Amman, Jordan%School of Public Health, Texas A&M University, College Station, Texas, USA%Department of Radiology, Faculty of Medicine, Istanbul University, Istanbul, Turkey%Radcliffe Department of Medicine, University of Oxford, Oxford, UK%Translational Gastroenterology Unit, University of Oxford, Oxford, UK%Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK
Wiley
Subjects:
Clinical medicine
Contrast agents
Hepatitis
hepatocellular cancer
Hypertension
imaging biomarker
Liver cancer
Liver cirrhosis
Liver diseases
Liver MultiScan
Medical diagnosis
Medical prognosis
MR elastography
portal hypertension
Radiation
Ultrasonic imaging
Liver MultiScan
imaging biomarker
portal hypertension
MR elastography
hepatocellular cancer
liver cirrhosis
ISSN:2770-5846, 2770-5838, 2770-5846
Online Access:Get full text
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Summary:Liver magnetic resonance imaging (MRI) has seen a massive increase in its use over the last decades. Since its first description in the early 1980s, contrast‐enhanced MRI is now the gold standard for the diagnosis of hepatocellular cancer in patients with liver cirrhosis. Techniques like magnetic resonance (MR) elastography and combinations of multiple MR parameters in single scanning protocols are now available and these are opening new possibilities for the assessment of multiple aspects of disease in patients with liver cirrhosis. In this narrative review, we provide an overview of the use of MRI in patients with cirrhosis for the diagnosis of and screening for liver cancer, for the diagnosis of cirrhosis and prediction of long‐term outcomes, and for the evaluation of portal hypertension. With the multitude of techniques now available and the number of cirrhosis aspects that can be assessed by single scans make the study and application of MRI an attractive target in the search for a technique for use in this group of patients that often have to attend for multiple appointments and multiple tests, including invasive investigations. Magnetic resonance imaging (MRI) with gadolinium contrast is the current gold standard for the diagnosis of hepatocellular cancer (HCC) in patients with liver cirrhosis (top panel). Recent developments have seen new applications of magnetic resonance (MR) in more indications including screening for HCC, diagnosis of cirrhosis, risk stratification for future decompensation, and portal hypertension assessment (middle panel). It is possible that in the future that multiple MR modalities will be combined into single scanning sessions to provide data for multiple indications (bottom panel). Key points Contrast‐enhanced magnetic resonance imaging is the current gold standard for diagnosis of hepatocellular cancer (HCC) in patients with cirrhosis. Magnetic resonance techniques including elastography and Liver MultiScan (Perspectum Ltd.) have recently seen applications in diagnosis and risk stratification of cirrhosis, screening for HCC and ass.
Bibliography:Managing Editor: Ningning Wang
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ISSN:2770-5846
2770-5838
2770-5846
DOI:10.1002/poh2.6