Drug-induced ototoxicity: Mechanisms, Pharmacogenetics, and protective strategies

Drug ototoxicity limits the quality of life of patients after treatment, having serious consequences, especially for psychosocial development of children. Although the ototoxicity of many drugs resolves after treatment discontinuation, the use of platinum derivatives and aminoglycosides is associate...

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Vydáno v:	Clinical pharmacology and therapeutics Ročník 101; číslo 4; s. 491
Hlavní autoři:	Lanvers-Kaminsky, C, Zehnhoff-Dinnesen, Ag Am, Parfitt, R, Ciarimboli, G
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.04.2017
Témata:	Aminoglycosides - adverse effects Animals Antineoplastic Agents - adverse effects Child Drug-Related Side Effects and Adverse Reactions - epidemiology Drug-Related Side Effects and Adverse Reactions - genetics Drug-Related Side Effects and Adverse Reactions - prevention & control Ear - physiopathology Hearing Loss - chemically induced Hearing Loss - epidemiology Hearing Loss - genetics Hearing Loss - physiopathology Hearing Loss - prevention & control Humans Pharmacogenetics
ISSN:	1532-6535, 1532-6535
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