Prime editing in plants and mammalian cells: Mechanism, achievements, limitations, and future prospects

Clustered, regularly interspaced, short palindromic repeat (CRISPR)/CRISPR‐associated protein (CRISPR/Cas) system has revolutionized genetic research in the life sciences. Four classes of CRISPR/Cas‐derived genome editing agents, such as nuclease, base editor, recombinase, and prime editor have been...

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Bibliographic Details
Published in:	BioEssays Vol. 44; no. 9; pp. e2200032 - n/a
Main Authors:	Hillary, V. Edwin, Ceasar, S. Antony
Format:	Journal Article
Language:	English
Published:	Cambridge Wiley Subscription Services, Inc 01.09.2022
Subjects:	base editing Cas9 H840 nickase CRISPR CRISPR/Cas Editing gene editing genome Genomes Mammalian cells Mammals Nuclease pegRNA plants prime editing Recombinase recombinases researchers
ISSN:	0265-9247, 1521-1878, 1521-1878
Online Access:	Get full text
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