Defective cortical drive to muscle in Parkinson's disease and its improvement with levodopa

We recorded whole-scalp magnetoencephalographic (MEG) signals simultaneously with surface electromyographic (EMG) activity from eight patients with Parkinson's disease after withdrawal and reinstatement of treatment with levodopa. Variations were seen in the coherence between the forearm extens...

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Bibliographic Details
Published in:	Brain (London, England : 1878) Vol. 125; no. Pt 3; p. 491
Main Authors:	Salenius, Stephan, Avikainen, Sari, Kaakkola, Seppo, Hari, Riitta, Brown, Peter
Format:	Journal Article
Language:	English
Published:	England 01.03.2002
Subjects:	Adult Aged Anterior Horn Cells - drug effects Anterior Horn Cells - physiology Antiparkinson Agents - therapeutic use Basal Ganglia - drug effects Basal Ganglia - physiopathology Biological Clocks - drug effects Biological Clocks - physiology Cortical Synchronization - drug effects Efferent Pathways - drug effects Efferent Pathways - physiopathology Electromyography Female Humans Levodopa - therapeutic use Magnetoencephalography Male Middle Aged Motor Cortex - drug effects Motor Cortex - physiopathology Muscle Contraction - drug effects Muscle Contraction - physiology Muscle, Skeletal - drug effects Muscle, Skeletal - physiopathology Parkinson Disease - drug therapy Parkinson Disease - pathology Parkinson Disease - physiopathology Recovery of Function - drug effects Recovery of Function - physiology Treatment Outcome
ISSN:	0006-8950
Online Access:	Get more information
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