Imputation Server PGS: an automated approach to calculate polygenic risk scores on imputation servers

Polygenic scores (PGS) enable the prediction of genetic predisposition for a wide range of traits and diseases by calculating the weighted sum of allele dosages for genetic variants associated with the trait or disease in question. Present approaches for calculating PGS from genotypes are often inef...

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Vydané v:	Nucleic acids research Ročník 52; číslo W1; s. W70 - W77
Hlavní autori:	Forer, Lukas, Taliun, Daniel, LeFaive, Jonathon, Smith, Albert V, Boughton, Andrew P, Coassin, Stefan, Lamina, Claudia, Kronenberg, Florian, Fuchsberger, Christian, Schönherr, Sebastian
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England Oxford University Press 05.07.2024
Predmet:	Alleles Genetic Predisposition to Disease Genetic Risk Score Genome-Wide Association Study - methods Genotype Humans Internet Multifactorial Inheritance - genetics Polymorphism, Single Nucleotide Software Web Server Issue
ISSN:	0305-1048, 1362-4962, 1362-4962
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