Cell types involved in allergic asthma and their use in in vitro models to assess respiratory sensitization

This review first describes the mechanism and cell types involved in allergic asthma, which is a complex clinical disease characterized by airway obstruction, airway inflammation and airway hyperresponsiveness to a variety of stimuli. The development of allergic asthma exists of three phases, namely...

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Veröffentlicht in:	Toxicology in vitro Jg. 22; H. 6; S. 1419 - 1431
Hauptverfasser:	Verstraelen, S., Bloemen, K., Nelissen, I., Witters, H., Schoeters, G., Heuvel, R. Van Den
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Elsevier Ltd 01.09.2008
Schlagworte:	Allergens - immunology Allergens - metabolism Allergic asthma Animals Asthma - immunology Asthma - metabolism Humans In vitro models Models, Biological Occupational asthma Occupational Diseases - immunology Occupational Diseases - metabolism Occupational Exposure - adverse effects Respiratory sensitization Respiratory System - cytology Respiratory System - immunology CD40L CXCL RANTES MHC AHR SLC BECs MDC TNF HETE LLNA Th GM-CSF CD34-DC Mo-DC IL EU VCAM TGF MIP EAR Respiratory sensitization CXCR Ig NO In vitro models SAR SAEC HDI ATCC IFN OA DCs RADS NHBE ASM DSMZ PGs Occupational asthma APCs Allergic asthma Ad12SV40 ICAM PMA LTs BAL CCL REACH 3D CCR HMW LC LMW SCF TARC FcεR MCP LAR
ISSN:	0887-2333
Online-Zugang:	Volltext
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