Prior vaccination prevents overactivation of innate immune responses during COVID-19 breakthrough infection

At this stage in the COVID-19 pandemic, most infections are "breakthrough" infections that occur in individuals with prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure. To refine long-term vaccine strategies against emerging variants, we examined both innate and ad...

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Bibliographic Details
Published in:	Science translational medicine Vol. 17; no. 783; p. eadq1086
Main Authors:	Chan, Leslie, Pinedo, Kassandra, Stabile, Mikayla A, Hamlin, Rebecca E, Pienkos, Shaun M, Ratnasiri, Kalani, Yang, Samuel, Blomkalns, Andra L, Nadeau, Kari C, Pulendran, Bali, O'Hara, Ruth, Rogers, Angela J, Holmes, Susan P, Blish, Catherine A
Format:	Journal Article
Language:	English
Published:	United States 29.01.2025
Subjects:	Adaptive Immunity Adult Breakthrough Infections COVID-19 - immunology COVID-19 - prevention & control COVID-19 Vaccines - immunology Female Humans Immunity, Innate - immunology Killer Cells, Natural - immunology Male Middle Aged Monocytes - immunology Proteomics SARS-CoV-2 - immunology Transcriptome Vaccination
ISSN:	1946-6242, 1946-6242
Online Access:	Get more information
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