Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways

In most tissues, cells are exposed to frequent changes in levels of oxidative stress and inflammation. Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and nuclear factor-κB (NF-κB) are the two key transcription factors that regulate cellular responses to oxidative stress and inflammation respecti...

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Bibliographic Details
Published in:	Biochemical Society transactions Vol. 43; no. 4; pp. 621 - 626
Main Authors:	Wardyn, Joanna D, Ponsford, Amy H, Sanderson, Christopher M
Format:	Journal Article
Language:	English
Published:	England 01.08.2015
Subjects:	Animals Cytokines - metabolism Gene Expression Regulation Humans Nervous System Diseases - drug therapy Nervous System Diseases - genetics Nervous System Diseases - metabolism NF-E2-Related Factor 2 - genetics NF-E2-Related Factor 2 - metabolism NF-kappa B - metabolism Oxidative Stress Signal Transduction Kelch-like ECH-associated protein 1 (Keap1) neurodegeneration inhibitor of kappa light polypeptide gene enhancer in B-cells kinase beta (IKKβ) haeme oxygenase-1 (HO-1) nuclear factor (erythroid-derived 2)-like 2 (Nrf2) nuclear factor-κB (NF-κB)
ISSN:	1470-8752
Online Access:	Get more information
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