EcoCyc: fusing model organism databases with systems biology

EcoCyc (http://EcoCyc.org) is a model organism database built on the genome sequence of Escherichia coli K-12 MG1655. Expert manual curation of the functions of individual E. coli gene products in EcoCyc has been based on information found in the experimental literature for E. coli K-12-derived stra...

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Vydané v:	Nucleic acids research Ročník 41; číslo D1; s. D605 - D612
Hlavní autori:	Keseler, Ingrid M., Mackie, Amanda, Peralta-Gil, Martin, Santos-Zavaleta, Alberto, Gama-Castro, Socorro, Bonavides-Martínez, César, Fulcher, Carol, Huerta, Araceli M., Kothari, Anamika, Krummenacker, Markus, Latendresse, Mario, Muñiz-Rascado, Luis, Ong, Quang, Paley, Suzanne, Schröder, Imke, Shearer, Alexander G., Subhraveti, Pallavi, Travers, Mike, Weerasinghe, Deepika, Weiss, Verena, Collado-Vides, Julio, Gunsalus, Robert P., Paulsen, Ian, Karp, Peter D.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England Oxford University Press 01.01.2013
Predmet:	Binding Sites Databases, Genetic Escherichia coli K12 - genetics Escherichia coli K12 - metabolism Escherichia coli Proteins - classification Escherichia coli Proteins - metabolism Gene Expression Regulation, Bacterial Internet Membrane Transport Proteins - classification Membrane Transport Proteins - metabolism Models, Genetic Molecular Sequence Annotation Phenotype Position-Specific Scoring Matrices Promoter Regions, Genetic Systems Biology Transcription Factors - metabolism Transcription, Genetic
ISSN:	0305-1048, 1362-4962, 1362-4962
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Popis
Shrnutí:	EcoCyc (http://EcoCyc.org) is a model organism database built on the genome sequence of Escherichia coli K-12 MG1655. Expert manual curation of the functions of individual E. coli gene products in EcoCyc has been based on information found in the experimental literature for E. coli K-12-derived strains. Updates to EcoCyc content continue to improve the comprehensive picture of E. coli biology. The utility of EcoCyc is enhanced by new tools available on the EcoCyc web site, and the development of EcoCyc as a teaching tool is increasing the impact of the knowledge collected in EcoCyc.
Bibliografia:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0305-1048 1362-4962 1362-4962
DOI:	10.1093/nar/gks1027