Detection and localization of surgically resectable cancers with a multi-analyte blood test

Earlier detection is key to reducing cancer deaths. Here, we describe a blood test that can detect eight common cancer types through assessment of the levels of circulating proteins and mutations in cell-free DNA. We applied this test, called CancerSEEK, to 1005 patients with nonmetastatic, clinical...

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Vydané v:	Science (American Association for the Advancement of Science) Ročník 359; číslo 6378; s. 926
Hlavní autori:	Cohen, Joshua D, Li, Lu, Wang, Yuxuan, Thoburn, Christopher, Afsari, Bahman, Danilova, Ludmila, Douville, Christopher, Javed, Ammar A, Wong, Fay, Mattox, Austin, Hruban, Ralph H, Wolfgang, Christopher L, Goggins, Michael G, Dal Molin, Marco, Wang, Tian-Li, Roden, Richard, Klein, Alison P, Ptak, Janine, Dobbyn, Lisa, Schaefer, Joy, Silliman, Natalie, Popoli, Maria, Vogelstein, Joshua T, Browne, James D, Schoen, Robert E, Brand, Randall E, Tie, Jeanne, Gibbs, Peter, Wong, Hui-Li, Mansfield, Aaron S, Jen, Jin, Hanash, Samir M, Falconi, Massimo, Allen, Peter J, Zhou, Shibin, Bettegowda, Chetan, Diaz, Jr, Luis A, Tomasetti, Cristian, Kinzler, Kenneth W, Vogelstein, Bert, Lennon, Anne Marie, Papadopoulos, Nickolas
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 23.02.2018
Predmet:	Circulating Tumor DNA - genetics Costs and Cost Analysis Early Detection of Cancer - economics Early Detection of Cancer - methods Hematologic Tests - economics Humans Mutation Neoplasm Proteins - blood Neoplasms - blood Neoplasms - diagnosis Neoplasms - genetics Neoplasms - surgery Polymerase Chain Reaction - methods
ISSN:	1095-9203, 1095-9203
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