Detection and localization of surgically resectable cancers with a multi-analyte blood test

Earlier detection is key to reducing cancer deaths. Here, we describe a blood test that can detect eight common cancer types through assessment of the levels of circulating proteins and mutations in cell-free DNA. We applied this test, called CancerSEEK, to 1005 patients with nonmetastatic, clinical...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) Jg. 359; H. 6378; S. 926
Hauptverfasser:	Cohen, Joshua D, Li, Lu, Wang, Yuxuan, Thoburn, Christopher, Afsari, Bahman, Danilova, Ludmila, Douville, Christopher, Javed, Ammar A, Wong, Fay, Mattox, Austin, Hruban, Ralph H, Wolfgang, Christopher L, Goggins, Michael G, Dal Molin, Marco, Wang, Tian-Li, Roden, Richard, Klein, Alison P, Ptak, Janine, Dobbyn, Lisa, Schaefer, Joy, Silliman, Natalie, Popoli, Maria, Vogelstein, Joshua T, Browne, James D, Schoen, Robert E, Brand, Randall E, Tie, Jeanne, Gibbs, Peter, Wong, Hui-Li, Mansfield, Aaron S, Jen, Jin, Hanash, Samir M, Falconi, Massimo, Allen, Peter J, Zhou, Shibin, Bettegowda, Chetan, Diaz, Jr, Luis A, Tomasetti, Cristian, Kinzler, Kenneth W, Vogelstein, Bert, Lennon, Anne Marie, Papadopoulos, Nickolas
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 23.02.2018
Schlagworte:	Circulating Tumor DNA - genetics Costs and Cost Analysis Early Detection of Cancer - economics Early Detection of Cancer - methods Hematologic Tests - economics Humans Mutation Neoplasm Proteins - blood Neoplasms - blood Neoplasms - diagnosis Neoplasms - genetics Neoplasms - surgery Polymerase Chain Reaction - methods
ISSN:	1095-9203, 1095-9203
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