Editorial of Special Issue “Multiple Sclerosis: From Diagnostic Biomarkers to Imaging and Clinical Predictors”

The presence of higher EDSS scores and lower whole brain volume at the baseline visit were both predictors of isolated cognitive decline. [...]40% of these patients were already classified as cognitively impaired at baseline [4]. [...]early detection of cognitive impairment can identify patients tha...

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Bibliographic Details
Published in:Diagnostics (Basel) Vol. 12; no. 2; p. 482
Main Authors: Jakimovski, Dejan, Zivadinov, Robert
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 13.02.2022
MDPI
Subjects:
Cognition & reasoning
Cognitive ability
Disability
Executive function
Magnetic resonance imaging
Multiple sclerosis
n/a
Neuropsychology
Pathology
Questionnaires
Software
Spinal cord
Urogenital system
ISSN:2075-4418, 2075-4418
Online Access:Get full text
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Summary:The presence of higher EDSS scores and lower whole brain volume at the baseline visit were both predictors of isolated cognitive decline. [...]40% of these patients were already classified as cognitively impaired at baseline [4]. [...]early detection of cognitive impairment can identify patients that are at risk for additional future cognitive decline. [...]streamlines of the uncinate fasciculus, inferior longitudinal fasciculus and corpus callosum were associated with verbal episodic and semantic memory performance [5]. [...]the work by Jewells et al. utilizes novel in vivo detection of microglia through PET detection of 18-kDa translocator protein (TSPO) radiotracer in demyelinating mice model of MS [13].
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ISSN:2075-4418
2075-4418
DOI:10.3390/diagnostics12020482