Role of mTORC1 in mechanically induced increases in translation and skeletal muscle mass

Skeletal muscle mass is, in part, regulated by the rate of mRNA translation (i.e., protein synthesis). The conserved serine/threonine kinase, mTOR (the mammalian/mechanistic target of rapamycin), found in the multiprotein complex, mTOR complex 1 (mTORC1), is a major positive regulator of protein syn...

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Vydané v:	Journal of applied physiology (1985) Ročník 127; číslo 2; s. 581
Hlavný autor:	Goodman, Craig A
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.08.2019
Predmet:	translation protein synthesis muscle atrophy muscle hypertrophy mTORC1
ISSN:	1522-1601, 1522-1601
On-line prístup:	Zistit podrobnosti o prístupe
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