Placental syndromes and maternal cardiovascular health

The placental syndromes gestational hypertension, preeclampsia and intrauterine growth restriction are associated with an increased cardiovascular risk to the mother later in life. In this review, we argue that a woman's pre-conception cardiovascular health drives both the development of placen...

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Bibliographic Details
Published in:Clinical science (1979) Vol. 137; no. 16; p. 1211
Main Authors: Casey, Helen, Dennehy, Natalie, Fraser, Abigail, Lees, Christoph, McEniery, Carmel M, Scott, Kayley, Wilkinson, Ian B, Delles, Christian
Format: Journal Article
Language:English
Published: England 31.08.2023
Subjects:
Cardiovascular Diseases - etiology
Cardiovascular System
Female
Humans
Placenta
Pre-Eclampsia
Pregnancy
Syndrome
placenta
cardiovascular risk
preeclampsia
cardiovascular health
ISSN:1470-8736, 1470-8736
Online Access:Get more information
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Summary:The placental syndromes gestational hypertension, preeclampsia and intrauterine growth restriction are associated with an increased cardiovascular risk to the mother later in life. In this review, we argue that a woman's pre-conception cardiovascular health drives both the development of placental syndromes and long-term cardiovascular risk but acknowledge that placental syndromes can also contribute to future cardiovascular risk independent of pre-conception health. We describe how preclinical studies in models of preeclampsia inform our understanding of the links with later cardiovascular disease, and how current pre-pregnancy studies may explain relative contributions of both pre-conception factors and the occurrence of placental syndromes to long-term cardiovascular disease.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:1470-8736
1470-8736
DOI:10.1042/CS20211130