Neuronal differentiation strategies: insights from single-cell sequencing and machine learning

Neuronal replacement therapies rely on the differentiation of specific cell types from embryonic or induced pluripotent stem cells, or on the direct reprogramming of differentiated adult cells via the expression of transcription factors or signaling molecules. The factors used to induce differentiat...

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Bibliographic Details
Published in:	Development (Cambridge) Vol. 147; no. 23
Main Authors:	Konstantinides, Nikolaos, Desplan, Claude
Format:	Journal Article
Language:	English
Published:	England 08.12.2020
Subjects:	Animals Cell Differentiation - genetics Cellular Reprogramming - genetics Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Humans Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - metabolism Machine Learning Neural Stem Cells - cytology Neural Stem Cells - metabolism Neurons - cytology Neurons - metabolism Signal Transduction - genetics Single-Cell Analysis - methods Single-cell sequencing Neuronal replacement therapy Neuronal differentiation protocols In vitro differentiation Machine learning Neuronal development
ISSN:	1477-9129, 1477-9129
Online Access:	Get more information
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