The Eye as a Window to Systemic Infectious Diseases: Old Enemies, New Imaging

Background: Syphilis, tuberculosis and toxoplasmosis are major infectious diseases worldwide; all of them are multisystem pathologies and share a possible ocular involvement. In this context, a fundamental help for the definitive diagnosis is provided by the ophthalmologist, through clinical evaluat...

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Veröffentlicht in:Journal of clinical medicine Jg. 8; H. 9; S. 1392
Hauptverfasser: Pirani, Vittorio, Pelliccioni, Paolo, De Turris, Serena, Rosati, Alessandro, Franceschi, Alessandro, Cesari, Claudia, Nicolai, Michele, Mariotti, Cesare
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Switzerland MDPI 05.09.2019
Schlagworte:
indocyanine green angiography
fluorescein angiography
infectious uveitis
optical coherence tomography
toxoplasmosis
fundus autofluorescence
optical coherence tomography angiography
tuberculosis
syphilis
ISSN:2077-0383, 2077-0383
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Zusammenfassung:Background: Syphilis, tuberculosis and toxoplasmosis are major infectious diseases worldwide; all of them are multisystem pathologies and share a possible ocular involvement. In this context, a fundamental help for the definitive diagnosis is provided by the ophthalmologist, through clinical evaluation and with the aid of a multimodal imaging examination. Methods: We hereby describe selected cases who came to our attention and were visited in our eye clinic. In all clinics, the use of retinal and optic disc multimodal imaging during ophthalmological evaluation allowed to make a diagnosis of an infectious disease. Results: In our tertiary referral center more than 60 patients with syphilis, tuberculosis and toxoplasmosis have been evaluated in the last two years: In 60% of cases the ophthalmological evaluation was secondary to a previous diagnosis of an infectious disease, while in the remaining cases the ophthalmologist, with the help of a multimodal imaging examination and clinical evaluation, represented the physician who leads to the diagnosis. Conclusion: Our results confirm how in these life-threatening pathologies a prompt diagnosis is mandatory and may benefit from a multidisciplinary and multimodal imaging approach, especially during ophthalmological evaluation.
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ISSN:2077-0383
2077-0383
DOI:10.3390/jcm8091392