Perinatal iron deficiency alters the cardiac proteome and mitochondrial function in neonatal offspring

Iron deficiency (ID) is common during gestation and early infancy and can alter developmental trajectories with lasting consequences on cardiovascular health. Iron plays a critical role in systemic oxygen transport (via hemoglobin) and aerobic respiration (as a component of mitochondrial complexes)....

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Bibliographic Details
Published in:	American journal of physiology. Heart and circulatory physiology Vol. 328; no. 1; p. H101
Main Authors:	Holody, Claudia D, Woodman, Andrew G, Nie, Chunpeng, Liu, Si Ning, Young, Daniel, Wiedemeyer, Alyssa, Carpenter, Rowan, Noble, Ronan M N, Graf, Daniel, Dufour, Antoine, Lemieux, Hélène, Bourque, Stephane L
Format:	Journal Article
Language:	English
Published:	United States 01.01.2025
Subjects:	Anemia, Iron-Deficiency - metabolism Anemia, Iron-Deficiency - physiopathology Animals Animals, Newborn Disease Models, Animal Female Iron Deficiencies - metabolism Male Mitochondria, Heart - metabolism Mitochondrial Proteins - genetics Mitochondrial Proteins - metabolism Myocardium - metabolism Oxidative Stress Pregnancy Prenatal Exposure Delayed Effects - metabolism Proteome - metabolism Proteomics Rats Rats, Sprague-Dawley Sex Factors nutrition mitochondria DOHaD
ISSN:	1522-1539, 1522-1539
Online Access:	Get more information
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