CntA oxygenase substrate profile comparison and oxygen dependency of TMA production in Providencia rettgeri

CntA oxygenase is a Rieske 2S‐2Fe cluster‐containing protein that has been previously described as able to produce trimethylamine (TMA) from carnitine, gamma‐butyrobetaine, glycine betaine, and in one case, choline. TMA found in humans is exclusively of bacterial origin, and its metabolite, trimethy...

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Veröffentlicht in:	Journal of basic microbiology Jg. 58; H. 1; S. 52 - 59
Hauptverfasser:	Kalnins, Gints, Sevostjanovs, Eduards, Hartmane, Dace, Grinberga, Solveiga, Tars, Kaspars
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Germany 01.01.2018
Schlagworte:	atherosclerosis betaine carnitine Carnitine - metabolism cell culture choline CntA digestive system heart Humans metabolites Methylamines - metabolism Microbiota Oxidation-Reduction oxygen Oxygen - metabolism Oxygen - pharmacology oxygenases Oxygenases - metabolism Providencia - drug effects Providencia - enzymology Providencia - metabolism Providencia rettgeri renal failure Rieske oxygenase Substrate Specificity trimethylamine CntA trimethylamine carnitine Rieske oxygenase
ISSN:	0233-111X, 1521-4028, 1521-4028
Online-Zugang:	Volltext
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