Development and evaluation of a simple and easy high‐performance liquid chromatography–ultraviolet system simultaneously suitable for determination of 24 anti‐epileptic drugs in plasma

We aim to establish a simple and easy high‐performance liquid chromatography system coupled with an ultraviolet detector suitable for simultaneous determination of 24 antiepileptic drugs in human plasma. Optimized chromatographic separation was performed on a ZORBAX Eclipse Plus‐C18 (4.6 × 150 mm2,...

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Bibliographic Details
Published in:	Journal of separation science Vol. 45; no. 13; pp. 2161 - 2176
Main Authors:	Zhao, Yan‐lin, Zhao, Lin‐lin, you, Yu‐xin, Zheng, Xiao‐xiao, Du, Yan, Tang, Dao‐quan
Format:	Journal Article
Language:	English
Published:	Weinheim Wiley Subscription Services, Inc 01.07.2022
Subjects:	Acetonitrile antiepileptic drugs Blood plasma Chromatography Drugs Ethyl acetate high performance liquid chromatography humans Ions KDP crystals Liquid chromatography patient with epilepsy patients Plasma potassium dihydrogen phosphate Potassium phosphates rats separation standard deviation temperature therapeutic drug monitoring Ultraviolet detectors wavelengths
ISSN:	1615-9306, 1615-9314, 1615-9314
Online Access:	Get full text
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