Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors

Central antinociceptive effects of cannabinoids have been well documented. However, relatively little is known about the peripheral effects of the cannabinoids on inflammation. In the present study, we evaluated the effects of peripherally administered cannabinoids on three indices of inflammation:...

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Veröffentlicht in:	Pain (Amsterdam) Jg. 75; H. 1; S. 111
Hauptverfasser:	Richardson, Jennelle Durnett, Kilo, Sonja, Hargreaves, Kenneth M
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.03.1998
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Arachidonic Acids - pharmacology Calcitonin Gene-Related Peptide - metabolism Capillary Permeability - drug effects Capsaicin - pharmacology Carrageenan Edema - chemically induced Edema - prevention & control Endocannabinoids Hindlimb - blood supply Hyperalgesia - chemically induced Hyperalgesia - physiopathology Hyperalgesia - prevention & control Male Polyunsaturated Alkamides Rats Rats, Sprague-Dawley Receptors, Cannabinoid Receptors, Drug - drug effects Receptors, Drug - physiology Skin - drug effects Skin - metabolism
ISSN:	0304-3959, 1872-6623
Online-Zugang:	Weitere Angaben
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