Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors

Central antinociceptive effects of cannabinoids have been well documented. However, relatively little is known about the peripheral effects of the cannabinoids on inflammation. In the present study, we evaluated the effects of peripherally administered cannabinoids on three indices of inflammation:...

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Bibliographic Details
Published in:	Pain (Amsterdam) Vol. 75; no. 1; p. 111
Main Authors:	Richardson, Jennelle Durnett, Kilo, Sonja, Hargreaves, Kenneth M
Format:	Journal Article
Language:	English
Published:	United States 01.03.1998
Subjects:	Animals Anti-Inflammatory Agents - pharmacology Arachidonic Acids - pharmacology Calcitonin Gene-Related Peptide - metabolism Capillary Permeability - drug effects Capsaicin - pharmacology Carrageenan Edema - chemically induced Edema - prevention & control Endocannabinoids Hindlimb - blood supply Hyperalgesia - chemically induced Hyperalgesia - physiopathology Hyperalgesia - prevention & control Male Polyunsaturated Alkamides Rats Rats, Sprague-Dawley Receptors, Cannabinoid Receptors, Drug - drug effects Receptors, Drug - physiology Skin - drug effects Skin - metabolism
ISSN:	0304-3959, 1872-6623
Online Access:	Get more information
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