Serine-Phosphorylated STAT3 Promotes Tumorigenesis via Modulation of RNA Polymerase Transcriptional Activity

Deregulated activation of the latent oncogenic transcription factor STAT3 in many human epithelial malignancies, including gastric cancer, has invariably been associated with its canonical tyrosine phosphorylation and enhanced transcriptional activity. By contrast, serine phosphorylation (pS) of STA...

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Bibliographic Details
Published in:Cancer research (Chicago, Ill.) Vol. 79; no. 20; p. 5272
Main Authors: Balic, Jesse J, Garama, Daniel J, Saad, Mohamed I, Yu, Liang, West, Alison C, West, Alice J, Livis, Thaleia, Bhathal, Prithi S, Gough, Daniel J, Jenkins, Brendan J
Format: Journal Article
Language:English
Published: United States 15.10.2019
ISSN:1538-7445, 1538-7445
Online Access:Get more information
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